Multidimensional Metabolic Engineering for Constructing Efficient Cell Factories [0.03%]
用于构建高效细胞工厂的多维代谢工程
Jianhui Liu,Jin Hou
Jianhui Liu
Microbial production of medium-chain fatty acids (MCFAs) is challenging, as they are rare metabolites and toxic to cells. Recently, Zhu et al. performed multidimensional engineering in Saccharomyces cerevisiae, including engineering fatty a...
Options to Reform the European Union Legislation on GMOs: Post-authorization and Beyond [0.03%]
欧盟 GMO立法改革选项：上市后监管及其他
Dennis Eriksson,René Custers,Karin Edvardsson Björnberg et al.
Dennis Eriksson et al.
We discuss options to reform the EU genetically modified organism (GMO) regulatory framework, make risk assessment and decision-making more consistent with scientific principles, and lay the groundwork for international coherence. In this t...
Plant Aromatic Prenyltransferases: Tools for Microbial Cell Factories [0.03%]
植物芳香族倍半萜转移酶：用于微生物细胞工厂的工具
Wouter J C de Bruijn,Mark Levisson,Jules Beekwilder et al.
Wouter J C de Bruijn et al.
In plants, prenylation of aromatic compounds, such as (iso)flavonoids and stilbenoids, by membrane-bound prenyltransferases (PTs), is an essential step in the biosynthesis of many bioactive compounds. Prenylated aromatic compounds have vari...
New Cognitive Neurotechnology Facilitates Studies of Cortical-Subcortical Interactions [0.03%]
新的认知神经技术有助于皮层和皮层下结构相互作用的研究
Byoung-Kyong Min,Matti S Hämäläinen,Dimitrios Pantazis
Byoung-Kyong Min
Most of the studies employing neuroimaging have focused on cortical and subcortical signals individually to obtain neurophysiological signatures of cognitive functions. However, understanding the dynamic communication between the cortex and...
Options to Reform the European Union Legislation on GMOs: Risk Governance [0.03%]
欧盟就转基因立法改革的选择：风险治理
Dennis Eriksson,René Custers,Karin Edvardsson Björnberg et al.
Dennis Eriksson et al.
Here, we discuss options to reform the EU genetically modified organism (GMO) regulatory framework, to make risk assessment and decision-making more consistent with scientific principles, and to lay the groundwork for international coherenc...
Options to Reform the European Union Legislation on GMOs: Scope and Definitions [0.03%]
欧盟能否对转基因立法进行改革：范围和定义
Dennis Eriksson,René Custers,Karin Edvardsson Björnberg et al.
Dennis Eriksson et al.
We discuss options to reform the EU genetically modified organisms (GMO) regulatory framework, make risk assessment and decision-making more consistent with scientific principles, and lay the groundwork for international coherence. The firs...
Xianhao Xu,Yanfeng Liu,Guocheng Du et al.
Xianhao Xu et al.
Engineering microbial cells to efficiently synthesize high-value-added natural products has received increasing attention in recent years. In this review, we describe the pipeline to build chassis cells for natural product production. First...
Geneva Statement on Heritable Human Genome Editing: The Need for Course Correction [0.03%]
关于可遗传人类基因组编辑的日内瓦声明：亟需纠正轨道
Roberto Andorno,Françoise Baylis,Marcy Darnovsky et al.
Roberto Andorno et al.
As public interest advocates, policy experts, bioethicists, and scientists, we call for a course correction in public discussions about heritable human genome editing. Clarifying misrepresentations, centering societal consequences and conce...
Weizhu Zeng,Likun Guo,Sha Xu et al.
Weizhu Zeng et al.
Based on the development of automatic devices and rapid assay methods, various high-throughput screening (HTS) strategies have been established for improving the performance of industrial microorganisms. We discuss the most significant fact...
Synthetic Biochemistry: The Bio-inspired Cell-Free Approach to Commodity Chemical Production [0.03%]
合成生物化学：向大宗化学品生产的生物启发性细胞 free 方法
James U Bowie,Saken Sherkhanov,Tyler P Korman et al.
James U Bowie et al.
Metabolic engineering efforts that harness living organisms to produce natural products and other useful chemicals face inherent difficulties because the maintenance of life processes often runs counter to our desire to maximize important p...