Darleen A Sandoval
Darleen A Sandoval
Désirée Schatton,Christian Frezza
Désirée Schatton
Widening research horizons on metabolic dysfunction-associated steatotic liver disease and cancer [0.03%]
扩大代谢功能障碍相关肝脂肪变性疾病和癌症的研究视野
Amedeo Lonardo,Norbert Stefan,Alessandro Mantovani
Amedeo Lonardo
Liver fibrosis and biological sex variably modulate the risks of hepatocellular carcinoma (HCC) and extrahepatic cancers (EHCs) arising in the context of metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we highlight h...
Targeting cholesterol-dependent adrenal steroidogenesis for management of primary aldosteronism [0.03%]
针对胆固醇依赖的肾上腺类固醇生成治疗原发性醛固酮增多症
Hao Wu,Hongbo He,Tong Han et al.
Hao Wu et al.
Primary aldosteronism (PA) is a common, salt-sensitive form of endocrine hypertension. Compared with essential hypertension (EH), PA is more susceptible to cardiorenal complications and metabolic risks. However, PA has a low screening rate ...
Beta-hydroxybutyrate [0.03%]
β-羟丁酸
Sidharth S Madhavan,Brianna J Stubbs
Sidharth S Madhavan
Elisabeth Wyart,Giovanna Carrà,Elia Angelino et al.
Elisabeth Wyart et al.
Cachexia is a complex metabolic disorder characterized by negative energy balance due to increased consumption and lowered intake, leading to progressive tissue wasting and inefficient energy distribution. Once considered as passive bystand...
Gut feelings on short-chain fatty acids to regulate respiratory health [0.03%]
肠道中的短链脂肪酸在调节呼吸健康方面的作用初探
Samantha N Rowland,Christopher G Green,John R Halliwill et al.
Samantha N Rowland et al.
Respiratory infections and diseases pose significant challenges to society and healthcare systems, underscoring the need for preventative and therapeutic strategies. Recent research in rodent models indicates that short-chain fatty acids (S...
Peter S Hamblin,Anthony W Russell,Stella Talic et al.
Peter S Hamblin et al.
With the rising prevalence of type 2 diabetes mellitus (T2DM) and obesity, several previously under-recognised complications associated with T2DM are becoming more evident. The most common of these emerging complications are metabolic dysfu...
Tumor-intrinsic regulators of the immune-cold microenvironment of prostate cancer [0.03%]
前列腺癌免疫微环境冷因素的肿瘤内在调节因子
Lourdes Brea,Jindan Yu
Lourdes Brea
Prostate cancer (PC) is a notoriously immune-cold tumor in that it often lacks substantial infiltration by antitumor immune cells, and in advanced diseases such as neuroendocrine PC, it could be devoid of immune cells. A majority of PC pati...
Sex- and endurance training-mediated cardiovascular protection through lipids during exercise [0.03%]
运动过程中性激素和耐力训练通过脂质介导的心血管保护作用
Julia An,Ariel S Thorson,David H Wasserman et al.
Julia An et al.
Premenopausal women and endurance-trained individuals of either sex have reduced cardiovascular disease (CVD) risk. Endurance training shifts fuel selection towards fats to spare carbohydrates; interestingly, women prioritize fats as an ene...