Ariane R Panzer,Susan V Lynch
Ariane R Panzer
Relationships between gut microbiome perturbation and autism spectrum disorder (ASD) have been observed in several human studies, but the functional implications and molecular mechanisms by which microbes may influence disease symptomology ...
High-Intensity Interval Training: Methodological Considerations for Interpreting Results and Conducting Research [0.03%]
高强度间歇训练：解释结果和开展研究的方法学考虑
Leonardo Vidal Andreato
Leonardo Vidal Andreato
In recent years, high-intensity interval training (HIIT) has gained prominence in the health and fitness area, becoming a worldwide trend. Given the positive results of HIIT, researchers have compared it with moderate-intensity continuous t...
Tyler C Beck,Thomas A Dix,Russell A Norris
Tyler C Beck
Muscle Lipid Droplets: Cellular Signaling to Exercise Physiology and Beyond [0.03%]
肌肉脂滴：从细胞信号转导到运动生理学及以后
Jacob T Seibert,Charles P Najt,Timothy D Heden et al.
Jacob T Seibert et al.
Conventionally viewed as energy storage depots, lipid droplets (LDs) play a central role in muscle lipid metabolism and intracellular signaling, as recognized by recent advances in our biological understanding. Specific subpopulations of mu...
The Sex Bias of Cancer [0.03%]
癌症的性别偏向性研究
Ana Raquel Costa,Mariana Lança de Oliveira,Inês Cruz et al.
Ana Raquel Costa et al.
In hormone-dependent organs, sex hormones and dysregulated hormone signaling have well-documented roles in cancers of the breast and female reproductive organs including endometrium and ovary, as well as in prostate and testicular cancers i...
Xiangyi Kong,Ran Gao,Zhongzhao Wang et al.
Xiangyi Kong et al.
Melatonin has significant inhibitory effects in numerous cancers, especially breast cancer. In estrogen receptor (ER)-positive human breast cancer, the oncostatic actions of melatonin are mainly achieved by suppressing ER mRNA expression an...
Teresa Mezza,Chiara M A Cefalo,Francesca Cinti et al.
Teresa Mezza et al.
Although it is well established that diabetes can also develop as a result of diseases or maneuvers on the exocrine pancreas, the complex relationship between glucose disorders and underlying pancreatic disease is still debated. There is ev...
Michael J Bertoldo,Johan Smitz,Lindsay E Wu et al.
Michael J Bertoldo et al.
Childhood cancer patients undergoing cancer therapy can be rendered infertile during adulthood. With more girls surviving cancer, fertility preservation in young cancer patients is a major clinical challenge. Advances in egg culture may off...
Xu Wang,Yi Wang,Victor Antony et al.
Xu Wang et al.
Metabolic diseases pose a tremendous health threat in both developed and developing countries. The pathophysiology of metabolic diseases is complex but has been shown to be closely associated with sterile inflammation, which is initiated by...
Apolipoprotein E Effects on Mammalian Ovarian Steroidogenesis and Human Fertility [0.03%]
载脂蛋白E对哺乳动物卵巢性类固醇生成和人类生育的影响
Reinaldo Barreto Oriá,Juliana Zani de Almeida,Carolyne Neves Moreira et al.
Reinaldo Barreto Oriá et al.
Apolipoprotein E (ApoE) is a glycoprotein consisting of 299 amino acids, highly produced in the mammalian ovaries. The main function of the ApoE is to transport cholesterol from the peripheral tissues to be metabolized in the liver. In huma...