Shiying Shao,Ruping Pan,Yong Chen
Shiying Shao
Application of autologous platelet-rich plasma (PRP), especially leukocyte- and platelet-rich fibrin (L-PRF), has emerged as a promising adjuvant therapy for the treatment of diabetic foot ulcers (DFUs). Conflicting results of PRP efficacy ...
Time for Novel Strategies to Mitigate Cardiometabolic Risk in Shift Workers [0.03%]
应对轮班工作人群心血管代谢风险的新型策略刻不容缓
Maaike Schilperoort,Patrick C N Rensen,Sander Kooijman
Maaike Schilperoort
Circadian disruption induced by shift work is robustly associated with obesity, diabetes, and cardiovascular disease in humans. Less well-known are the mechanisms underlying these associations, and the effectiveness of strategies to reduce ...
Insights Into Mechanisms of GDF15 and Receptor GFRAL: Therapeutic Targets [0.03%]
GDF15和受体GFRAL的作用机制研究：治疗靶点的启示
Luc Rochette,Marianne Zeller,Yves Cottin et al.
Luc Rochette et al.
Growth and differentiation factor 15 (GDF15) belongs to the transforming growth factor-β (TGF-β) superfamily proteins. GDF15 acts as an inflammatory marker, and it plays a role in pathogenesis of tumors, ischemic diseases, metabolic disor...
Cardiovascular Manifestations and Mechanisms in Patients with COVID-19 [0.03%]
COVID-19患者的临床表现及机制(心血管方面)
Qingyu Dou,Xin Wei,Kehua Zhou et al.
Qingyu Dou et al.
Coronavirus disease 2019 (COVID-19) patients with pre-existing cardiovascular disease (CVD) or with cardiovascular complications have a higher risk of mortality. The main cardiovascular complications of COVID-19 include acute cardiac injury...
Novel Strategies to Protect and Visualize Pancreatic β Cells in Diabetes [0.03%]
糖尿病中保护和可视化胰腺β细胞的新策略
Esteban N Gurzov,Pu Chun Ke,Ulf Ahlgren et al.
Esteban N Gurzov et al.
A common feature in the pathophysiology of different types of diabetes is the reduction of β cell mass and/or impairment of β cell function. Diagnosis and treatment of type 1 and type 2 diabetes is currently hampered by a lack of reliable...
Intestinal Organoids: A Tool for Modelling Diet-Microbiome-Host Interactions [0.03%]
肠道类器官：一种模拟饮食-微生物群-宿主相互作用的工具
Josep Rubert,Pawel J Schweiger,Fulvio Mattivi et al.
Josep Rubert et al.
Dietary patterns, microbiome dysbiosis, and gut microbial metabolites (GMMs) have a pivotal role in the homeostasis of intestinal epithelial cells and in disease progression, such as that of colorectal cancer (CRC). Although GMMs and microo...
Blood Microbiota and Circulating Microbial Metabolites in Diabetes and Cardiovascular Disease [0.03%]
糖尿病和心血管疾病中的血液微生物群和循环的微生物代谢物
Ganesan Velmurugan,Vasudevan Dinakaran,Jeyaprakash Rajendhran et al.
Ganesan Velmurugan et al.
Diabetes and cardiovascular disease (CVD) have evolved as the leading cause of mortality and morbidity worldwide. In addition to traditional risk factors, recent studies have established that the human microbiota, particularly gut bacteria,...
Maria Luisa Brandi,Andrea Giustina
Maria Luisa Brandi
The recent coronavirus disease 2019 (COVID-19) pandemic showed a different severity in the disease between males and females. Men have been becoming severely ill at a higher rate than women. These data along with an age-dependent disease su...
Sitagliptin/Metformin: A New Medical Treatment in Polycystic Ovary Syndrome [0.03%]
西格列汀/二甲双胍：多囊卵巢综合征的新药物治疗方式
Delbar Daneshjou,Malek Soleimani Mehranjani,Shahrzad Zadeh Modarres et al.
Delbar Daneshjou et al.
Metformin has long been used in the treatment of polycystic ovarian syndrome (PCOS). Recently, sitagliptin has been reported to improve ovarian cycles and ovulation in PCOS. We suggest that a combination of sitagliptin and metformin can be ...
Pablo Guisado-Vasco,Marta Cano-Megías,Margarita Rodríguez-López et al.
Pablo Guisado-Vasco et al.