Hexose Transporters in Cancer: From Multifunctionality to Diagnosis and Therapy [0.03%]
癌细胞己糖转运蛋白：从多功能性到诊断和治疗
Carolina Echeverría,Francisco Nualart,Luciano Ferrada et al.
Carolina Echeverría et al.
Cancer cells increase their metabolic activity by enhancing glucose uptake through overexpression of hexose transporters (Gluts). Gluts also have the capacity to transport other molecules besides glucose, including fructose, mannose, and de...
Anna Maria Formenti,Alberto Dalla Volta,Luigi di Filippo et al.
Anna Maria Formenti et al.
Medical treatment of prostate cancer (PC) is multidisciplinary, resulting in prolonged survival. Androgen-deprivation therapy (ADT) can have negative effects on skeletal metabolism, particularly if combined with glucocorticoids. We discuss ...
Sergej M Ostojic
Sergej M Ostojic
Clinical applications of molecular hydrogen (H2) seem to favorably affect obesity-related metabolic biomarkers in peripheral tissues, yet whether H2 directly tackles obesity pathways in the brain remains elusive. I summarize here several mo...
Roles of TGF-β Superfamily Proteins in Extravillous Trophoblast Invasion [0.03%]
转化生长因子β超家族成员调控滋养外胚层细胞侵袭的功能及机制研究
Yan Li,Junhao Yan,Hsun-Ming Chang et al.
Yan Li et al.
Following embryo implantation, extravillous trophoblasts (EVTs) invade the maternal decidua to a certain extent during early pregnancy, which is critical for normal placentation and successful pregnancy in humans. Although sharing a similar...
Lin Zhang,Chudan Liu,Qingyan Jiang et al.
Lin Zhang et al.
Butyrate, a main product of gut microbial fermentation, has been recognized as an important mediator of gut microbiota regulation in whole body energy homeostasis. However, the mechanisms of butyrate metabolic control remain unclear. This r...
Abdul Rehman,Pál Pacher,György Haskó
Abdul Rehman
Macrophages are cells of the innate immune system that play myriad roles in the body. Macrophages are known to reside in endocrine glands, and a body of evidence now suggests that these cells interact closely with endocrine cells. Immune-en...
Altered Cholesterol and Lipid Synthesis Mediates Hyperinflammation in COVID-19 [0.03%]
胆固醇和脂质合成异常介导了COVID-19的过度炎症反应
Yahya Sohrabi,Holger Reinecke,Rinesh Godfrey
Yahya Sohrabi
Recent data have revealed that fructose-rich diet triggers inflammation and lipid synthesis. Furthermore, lipid metabolism, cholesterol synthesis and sterol regulatory element binding protein-2 (SREBP-2) activation correlates with coronavir...
Those Apples Don't Taste Like Oranges! Why 'Equalising' HIIT and MICT Protocols Does Not Make Sense [0.03%]
那些苹果不像是橙子！为什么“均衡化”高强度间歇训练和中等强度持续训练方案没有意义
Niels B J Vollaard,Richard S Metcalfe
Niels B J Vollaard
Christina E May,Monica Dus
Christina E May
Although genetics shapes our sense of taste to prefer some foods over others, taste sensation is plastic and changes with age, disease state, and nutrition. We have known for decades that diet composition can influence the way we perceive f...
Effects of Blood Flow Restriction Exercise and Possible Applications in Type 2 Diabetes [0.03%]
血液限制运动对2型糖尿病的疗效及可能应用
Nina Saatmann,Oana-Patricia Zaharia,Jeremy P Loenneke et al.
Nina Saatmann et al.
Blood flow restriction resistance training (BFRT) employs partial vascular occlusion of exercising muscles via inflation cuffs. Compared with high-load resistance training, mechanical load is markedly reduced with BFRT, but induces similar ...