COVID-19 and obesity: fighting two pandemics with intermittent fasting [0.03%]
新冠肺炎和肥胖：通过间歇性禁食抗击两种流行病
Kafi N Ealey,Joy Phillips,Hoon-Ki Sung
Kafi N Ealey
Obesity is strongly and independently associated with an increased risk of severe illness and death from coronavirus disease 2019 (COVID-19). The pathophysiological changes that result from elevated body weight lead to metabolic dysfunction...
Insulin resistance in cardiovascular disease, uremia, and peritoneal dialysis [0.03%]
胰岛素抵抗在心血管疾病、尿毒症和腹膜透析中的作用
Mark Lambie,Mario Bonomini,Simon J Davies et al.
Mark Lambie et al.
Diabetic nephropathy is highly correlated with the occurrence of other complications of type 1 diabetes (T1D) and type 2 diabetes (T2D) mellitus; for example, hypertension with cardiovascular disease (CVD) being the most frequent cause of d...
Blood factors as biomarkers in osteoporosis: points from the COVID-19 era [0.03%]
骨因子作为骨质疏松生物标志物的观点源自于COVID-19时代
Francesca Salamanna,Melania Maglio,Veronica Borsari et al.
Francesca Salamanna et al.
The restrictions adopted during the coronavirus disease 2019 (COVID-19) pandemic limiting direct medical consultations and access to healthcare centers reduced the participation of patients with chronic diseases, such as osteoporosis (OP), ...
Matthew Beymer,Claudia G Willmes
Matthew Beymer
One carbon metabolism and early development: a diet-dependent destiny [0.03%]
一碳代谢与早期胚胎发育：一种可塑的饮食依赖的命运机制
Hunter W Korsmo,Xinyin Jiang
Hunter W Korsmo
One carbon metabolism (OCM) is critical for early development, as it provides one carbon (1C) units for the biosynthesis of DNA, proteins, and lipids and epigenetic modification of the genome. Epigenetic marks established early in life can ...
Federica Rey,Gian Vincenzo Zuccotti,Stephana Carelli
Federica Rey
Long non-coding RNAs (lncRNAs) are being widely studied for their implications in physiological and diseases contexts but their functions and therapeutic potentials in metabolic diseases are far from clarified. Here, we report a summary of ...
Tissue engineering and 3D printing of bioartificial pancreas for regenerative medicine in diabetes [0.03%]
组织工程和生物人工胰腺的3D打印在糖尿病再生医学中的应用
Andreas Alvin Purnomo Soetedjo,Jia Min Lee,Hwee Hui Lau et al.
Andreas Alvin Purnomo Soetedjo et al.
Diabetes is a severe chronic disease worldwide. In various types of diabetes, the pancreatic beta cells fail to secrete sufficient insulin, at some point, to regulate blood glucose levels. Therefore, the replacement of dysfunctional pancrea...
Dietary lipids as regulators of reward processes: multimodal integration matters [0.03%]
饮食脂质作为奖赏过程调节因子的作用：多模态整合的影响不容忽视
Chloé Berland,Dana M Small,Serge Luquet et al.
Chloé Berland et al.
The abundance of energy-dense and palatable diets in the modern food environment tightly contributes to the obesity pandemic. The reward circuit participates to the regulation of body homeostasis by integrating energy-related signals with n...
Peripheral neurovascular link: an overview of interactions and in vitro models [0.03%]
外周神经血管联系：交互作用与体外模型概述
Afonso Malheiro,Paul Wieringa,Lorenzo Moroni
Afonso Malheiro
Nerves and blood vessels (BVs) establish extensive arborized networks to innervate tissues and deliver oxygen/metabolic support. Developmental cues direct the formation of these intricate and often overlapping patterns, which reflect close ...
Pomme I H G Simons,Olivier Valkenburg,Coen D A Stehouwer et al.
Pomme I H G Simons et al.
Over the past decade, there have been important breakthroughs in our understanding of the regulation and function of sex hormone-binding globulin (SHBG). A recent genome-wide association and Mendelian randomization study has provided new in...