Carolyn L Cummins,Ido Goldstein
Carolyn L Cummins
Glucocorticoids (GCs) are potent anti-inflammatory drugs. A new study by Auger et al. found that GCs increase itaconate, an anti-inflammatory tricarboxylic acid (TCA) cycle intermediate, by promoting movement of cytosolic pyruvate dehydroge...
Linqi Zhang,Xiao Wang,Xiao-Wei Chen
Linqi Zhang
Triglyceride-rich lipoproteins (TRLs) play essential roles in human health and disease by transporting bulk lipids into the circulation. This review summarizes the fundamental mechanisms and diverse factors governing lipoprotein production,...
Emilia Nunzi,Marilena Pariano,Claudio Costantini et al.
Emilia Nunzi et al.
As a result of a long evolutionary history, serotonin plays a variety of physiological roles, including neurological, cardiovascular, gastrointestinal, and endocrine functions. While many of these activities can be accommodated within the s...
Siyao Zhou,Wenqiang Chen,Hongbin Yang
Siyao Zhou
Shuke Xiao,Veronica L Li,Jonathan Z Long
Shuke Xiao
Cardioprotective benefits of metabolic surgery and GLP-1 receptor agonist-based therapies [0.03%]
代谢手术和GLP-1受体激动剂类疗法的心脏保护效益
Arianne Morissette,Erin E Mulvihill
Arianne Morissette
Individuals with excessive adipose tissue and type 2 diabetes mellitus (T2DM) face a heightened risk of cardiovascular morbidity and mortality. Metabolic surgery is an effective therapy for people with severe obesity to achieve significant ...
Pregnancy-induced metabolic reprogramming and regenerative responses to pro-aging stresses [0.03%]
妊娠引起的代谢重构和对促衰老刺激的再生应答
Dainan Yu,Lanfang Luo,Hongmei Wang et al.
Dainan Yu et al.
Pregnancy is associated with physiological adaptations that affect virtually all organs, enabling the mother to support the growing fetus and placenta while withstanding the demands of pregnancy. As a result, mammalian pregnancy is a unique...
Standardizing methodologies to study microplastics and nanoplastics in cardiovascular diseases [0.03%]
心血管疾病中微塑料和纳米塑料研究方法标准化
Yilin Pan,Suowen Xu,Xiubin Yang
Yilin Pan
Microplastics and nanoplastics (MNPs) are being recognized as new cardiovascular risk factors, impacting vascular cell functions and exacerbating atherosclerosis through diverse mechanisms. However, the varied concentrations of MNPs detecte...
Erica Pranzini,Luigi Ippolito,Elisa Pardella et al.
Erica Pranzini et al.
The success of disseminating cancer cells (DTCs) at specific metastatic sites is influenced by several metabolic factors. Even before DTCs arrival, metabolic conditioning from the primary tumor participates in creating a favorable premetast...
Jorge R Soliz-Rueda,Cristina Cuesta-Marti,Siobhain M OMahony et al.
Jorge R Soliz-Rueda et al.
Eating behaviour and circadian rhythms are closely related. The type, timing, and quantity of food consumed, and host circadian rhythms, directly influence the intestinal microbiota, which in turn impacts host circadian rhythms and regulate...