Impact of non-sugar sweeteners on metabolism beyond sweet taste perception [0.03%]
非糖甜味剂对代谢的影响超出了对甜味感知的作用
Herbert Herzog,Lei Zhang,Luigi Fontana et al.
Herbert Herzog et al.
Non-sugar sweeteners (NSS), low- or no-calorie alternatives to sugar, are marketed for weight loss and improved blood glucose control in people with diabetes. However, their health effects remain controversial. This review provides a brief ...
Stefano Auddino,Elena Aiello,Giuseppina Emanuela Grieco et al.
Stefano Auddino et al.
MicroRNAs (miRNAs) are noncoding RNA molecules that regulate gene expression post-transcriptionally and influence numerous biological processes. Aberrant miRNA expression is linked to diseases such as diabetes mellitus; indeed, miRNAs regul...
Adipose tissue-gut microbiome crosstalk in inflammation and thermogenesis [0.03%]
脂肪组织-肠道菌群在炎症和产热中的互作关系
Erin E Mauney,Marsha C Wibowo,Yu-Hua Tseng et al.
Erin E Mauney et al.
Previously characterized as inert fat depots, adipocytes are now recognized as dynamic mediators of inflammatory tone, metabolic health, and nutrient homeostasis. As endocrine organs, specialized depots of adipose tissue engage in crosstalk...
Huadong Chen,Pomme I H G Simons,Martijn C G J Brouwers
Huadong Chen
Recent genetic studies have implicated an active role for intrahepatic lipid accumulation in the pathogenesis of both polycystic ovary syndrome (PCOS) and cardiovascular disease. These new insights may provide novel (non)pharmacological opp...
Context-specific fatty acid uptake is a finely-tuned multi-level effort [0.03%]
上下文特定的脂肪酸摄取是一个精细调节的多层次过程
Juan Wang,Huiling Guo,Lang-Fan Zheng et al.
Juan Wang et al.
Fatty acids (FAs) are essential nutrients that play multiple roles in cellular activities. To meet cell-specific needs, cells exhibit differential uptake of FAs in diverse physiological or pathological contexts, coordinating to maintain met...
Miguel Ruiz-Cruz,Juan Roa,Manuel Tena-Sempere
Miguel Ruiz-Cruz
Casper M Sigvardsen,Michael M Richter,Sarah Engelbeen et al.
Casper M Sigvardsen et al.
Growth differentiation factor 15 (GDF15) is a member of the transforming growth factor-β (TGF-β) superfamily. Despite its identification over 20 years ago, the functions of GDF15 remain complex and not fully elucidated. Its concentration ...
Phosphatidylethanolamine [0.03%]
磷脂酰乙醇胺
Mackenzie T Primrose,Steven M Claypool
Mackenzie T Primrose
Junhong Lin,Yongfeng Lai,Fujia Lu et al.
Junhong Lin et al.
Five acyl-CoA synthetase long-chain family members (ACSLs) are responsible for catalyzing diverse long-chain fatty acids (LCFAs) into LCFA-acyl-coenzyme A (CoA) for their subsequent metabolism, including fatty acid oxidation (FAO), lipid sy...
Wenqiang Chen,C Ronald Kahn
Wenqiang Chen