Factors influencing the solubilization of membrane proteins from Escherichia coli membranes by styrene-maleic acid copolymers [0.03%]
聚苯乙烯-马来酸共聚物从大肠杆菌膜中溶解膜蛋白的影响因素分析
Adrian H Kopf,Jonas M Dörr,Martijn C Koorengevel et al.
Adrian H Kopf et al.
Styrene-maleic acid (SMA) copolymers are a promising alternative to detergents for the solubilization of membrane proteins. Here we employ Escherichia coli membranes containing KcsA as a model protein to investigate the influence of differe...
Influence of interfacial tryptophan residues on an arginine-flanked transmembrane helix [0.03%]
色氨酸间残基对带精氨酸的跨膜螺旋界面的影响分析
Sara J Sustich,Fahmida Afrose,Denise V Greathouse et al.
Sara J Sustich et al.
The transmembrane helices of membrane proteins often are flanked by interfacial charged or aromatic residues that potentially help to anchor the membrane-spanning protein. For isolated single-span helices, the interfacial residues may be es...
Cdr1p highlights the role of the non-hydrolytic ATP-binding site in driving drug translocation in asymmetric ABC pumps [0.03%]
Cdr1p揭示了非水解ATP结合位点在不对称ABC泵药物转运中的作用
Atanu Banerjee,Alexis Moreno,Mohammad Firoz Khan et al.
Atanu Banerjee et al.
ATP-binding cassette (ABC) transporters couple ATP binding and hydrolysis to the translocation of allocrites across membranes. Two shared nucleotide-binding sites (NBS) participate in this cycle. In asymmetric ABC pumps, only one of them hy...
Induction of non-lamellar phases in archaeal lipids at high temperature and high hydrostatic pressure by apolar polyisoprenoids [0.03%]
无极多异戊二烯在高温高压下诱导古菌脂质形成非层状相
Marta Salvador-Castell,Nicholas J Brooks,Judith Peters et al.
Marta Salvador-Castell et al.
It is now well established that cell membranes are much more than a barrier that separate the cytoplasm from the outside world. Regarding membrane's lipids and their self-assembling, the system is highly complex, for example, the cell membr...
Penetration of phospholipid membranes by poly-l-lysine depends on cholesterol and phospholipid composition [0.03%]
聚L-赖氨酸穿入磷脂膜依赖于胆固醇及磷脂组成
Amy Gorman,Khondker R Hossain,Flemming Cornelius et al.
Amy Gorman et al.
Clusters of positively-charged basic amino acid residues, particularly lysine, are known to promote the interaction of many peripheral membrane proteins with the cytoplasmic surface of the plasma membrane via electrostatic interactions. In ...
Role of membrane curvature on the activation/deactivation of Carnitine Palmitoyltransferase 1A: A coarse grain molecular dynamic study [0.03%]
粗粒化分子动力学模拟研究膜曲率对肉碱棕榈酰转移酶1A活/失活作用的影响
Ezequiel N Frigini,Exequiel E Barrera,Sergio Pantano et al.
Ezequiel N Frigini et al.
Carnitine Palmitoyltransferase 1A (CPT 1A) is an enzyme anchored to the outer mitochondrial membrane (OMM), where it regulates the passage of fatty acids into the mitochondria and intervenes in the process of β-oxidation of long-chain fatt...
Immobilization of natural lipid biomembranes and their interactions with choline carboxylates. A nanoplasmonic sensing study [0.03%]
天然脂质生物膜的固定及其与胆碱羧酸盐相互作用的纳米等离子体传感研究
Filip Duša,Wen Chen,Joanna Witos et al.
Filip Duša et al.
The cell membrane is mainly composed of lipid bilayers with inserted proteins and carbohydrates. Lipid bilayers made of purified or synthetic lipids are widely used for estimating the effect of target compounds on cell membranes. However, t...
Thermal behavior of a lipid-protein membrane model and the effects produced by anesthetics and neurotransmitters [0.03%]
脂蛋白膜模型的热行为及麻醉剂和神经递质造成的影响
Rosendo Pérez-Isidoro,J C Ruiz-Suárez
Rosendo Pérez-Isidoro
Despite decades of intense research to understand the phenomenon of anesthesia and its membrane-related changes in neural transmission, where lipids and proteins have been proposed as primary targets of anesthetics, the involved action mech...
Biophysical characterization of the insertion of two potent antimicrobial peptides-Pin2 and its variant Pin2[GVG] in biological model membranes [0.03%]
两种具有抗菌活性的多肽Pin2及其突变体Pin2[GVG]在生物模型膜中插入行为的生物物理研究
Brandt Bertrand,Sathishkumar Munusamy,José-Francisco Espinosa-Romero et al.
Brandt Bertrand et al.
The aim of this study was to investigate the factors that govern the activity and selectivity of two potent antimicrobial peptides (AMPs) using lipid membrane models of bacterial, erythrocyte and fungal cells. These models were used in calc...
Expression and detergent free purification and reconstitution of the plant plasma membrane Na+/H+ antiporter SOS1 overexpressed in Pichia pastoris [0.03%]
甲基球形酵母中过量表达的拟南芥质膜Na+/H+反向转运蛋白SOS1的表达、非去垢剂纯化和重构
Debajyoti Dutta,Mansoore Esmaili,Michael Overduin et al.
Debajyoti Dutta et al.
The plant plasma membrane Na+/H+ antiporter SOS1 (Salt Overlay Sensitive 1) of Arabidopsis thaliana is the major transporter extruding Na+ out of cells in exchange for an intracellular H+. The sodium extrusion process maintains a low intrac...