Igor Pokotylo,Marine Lebon-Navarro,Nathan Vallier et al.
Igor Pokotylo et al.
Plant cells generate lipid messengers such as phosphatidic acid, diacylglycerol, and phosphoinositides through rapid phospholipid remodeling, enabling the regulation of stress responses, ion transport, cytoskeletal organization, and membran...
Investigation of the impact of catechol on the fluidity of lipid monolayers [0.03%]
儿茶酚对脂质单分子层流体性影响的研究
Pauline Conigliaro,Marion Baudoin,Gilles Paboeuf et al.
Pauline Conigliaro et al.
In recent years, water pollution has become a critical issue due to population growth and rapid industrialization, with profound consequences for both environmental and public health. Among the key contributors are phenolic compounds, inclu...
Infrared spectral signatures of plasma-derived small extracellular vesicles reveal diagnostic potential of idiopathic Parkinson's disease detection [0.03%]
基于血浆外泌体的红外光谱标志物在特发性帕金森病诊断中的应用潜力
Sanskriti Rai,Abhay Mishra,Sadaqa Zehra et al.
Sanskriti Rai et al.
Background: Parkinson's disease (PD) is a progressive neurodegenerative disorder lacking reliable, early-stage diagnostic biomarkers. This study utilizes Fourier Transform Infrared (FTIR) spectroscopy to identify biochemi...
Structure/function relationships of mitochondrial protein carrier (SLC25A20) for carnitine/acylcarnitine: A review [0.03%]
肉毒碱/乙酰肉毒碱载体蛋白(SLC25A20)的结构和功能关系：综述
Nicola Giangregorio,Annamaria Tonazzi,Lara Console et al.
Nicola Giangregorio et al.
The mitochondrial carnitine/acylcarnitine carrier (CAC) is a member of the mitochondrial carrier (MC) family. It facilitates the import of acylcarnitines into the mitochondrial matrix in exchange for carnitine, playing a crucial role in the...
Mechanisms of blood-brain barrier penetration: A molecular dynamics study on R9 and MPG peptide translocation [0.03%]
血脑屏障渗透机制：R9和MPG肽穿过的分子动力学研究
Cintia Emi Yanaguibashi Leal,Nicola D&#x;Amelio,Benjamin Bouvier
Cintia Emi Yanaguibashi Leal
One of the major obstacles in treating diseases that affect the central nervous system is delivering drugs across the blood-brain-barrier (BBB). Cell-penetrating peptides (CPPs) can be used as delivery vectors, but their translocation mecha...
Differential lipid dynamics regulation by sterols in ceramide and sphingomyelin containing membranes [0.03%]
胆固醇对含有鞘氨醇和鞘磷脂膜的脂质动力学的不同调节作用
Jesus Ayala-Sanmartin,Antonin Lamazière
Jesus Ayala-Sanmartin
The role of cholesterol in membrane lipid organization and ordering has been evidenced over the past twenty years. The participation of cholesterol precursors and other cholesterol derivatives in the modulation of cell membrane physicochemi...
Purification and structural characterization of the tularemia membrane protein virulence factors CapB and CapC [0.03%]
兔热病膜蛋白毒力因素CapB和CapC的纯化与结构鉴定
M Eranjalee Ranaweera,Rebecca J Jernigan,Krisha S Boradia et al.
M Eranjalee Ranaweera et al.
Francisella tularensis, the causative agent of tularemia, relies on the CapBCA membrane protein complex for intracellular survival and virulence, yet none of its components have been structurally characterized. Here, we report successful re...
Mechanical and energetic insights into pore formation in asymmetric lipid bilayers [0.03%]
不对称脂质双层孔形成的机械和能量见解
Zhaoyang Li,Wenjue Chu,Minmin Xue et al.
Zhaoyang Li et al.
Compositional asymmetry is a hallmark of biological membranes and plays a crucial role in pore formation. However, the molecular mechanism by which leaflet asymmetry influences pore formation remains unclear. Here, we employed molecular dyn...
Membrane interactions of designed cyclic RW peptides by solid-state NMR spectroscopy [0.03%]
固体核磁共振光谱法设计的环形RW肽膜相互作用研究
Kathakali De,Christopher Aisenbrey,Maria Hoernke et al.
Kathakali De et al.
Antimicrobial peptides (AMPs) are hoped to complement classical antibiotics in view of increasing microbial resistance. We investigate two members of a family of designed cyclic AMPs with different activity and selectivity. The cyclic hexap...
Léa Poskin,Lionel Porcar,Sylvain Prévost et al.
Léa Poskin et al.
Membrane proteins are essential for cellular communication and are frequently key targets for pharmaceutical intervention. However, their structural and dynamical characterization remains limited due to challenges associated with protein pr...