Influence of lipid saturation on the structural properties of styrene maleic acid lipid nanoparticles (SMALPs) [0.03%]
脂质饱和度对苯乙烯-马来酸酐脂质纳米颗粒(SMALP)结构特性的影响
Evelyn A Okorafor,Emma A Gordon,Indra D Sahu et al.
Evelyn A Okorafor et al.
Membrane bilayers are complex three-dimensional structures whose molecular events in the deep dimensions of membrane lipids are crucial for understanding membrane function. This study investigates the interaction of coexisting membrane doma...
Evaluation of aquaporin Z water permeability in bilayers using droplet interface systems with internal-pressure-defined membrane tension [0.03%]
基于内部压力定义膜张力的液滴界面系统评估气孔素Z在双层中的水渗透性
Misuzu Ueki,Takahisa Maki,Masayuki Iwamoto
Misuzu Ueki
Cell membranes regulate water flow to maintain homeostasis, cell volume, and osmotic balance. Aquaporins (AQPs) enable selective water transport, making precise permeability measurements essential for understanding their function. The curre...
Effect of glucosylation for the vertical movement of cholesterol in bilayer membranes [0.03%]
糖基化对双层膜中胆固醇垂直位移的影响研究
Shinya Hanashima,Takafumi Asahina,Raymond Malabed et al.
Shinya Hanashima et al.
Cholesterol (Chol) in mammalian cell membranes facilitates the assembly of dynamic membrane domains that are involved in vital biological processes through lateral and transbilayer movements in the membranes. In the cell membranes, Chol und...
Elucidating the interactions of endocannabinoid-like neurotransmitters, N-acyltaurines and bovine serum albumin: Spectroscopic and computational approaches [0.03%]
内源性大麻素样神经递质、N-酰基牛磺酸和牛血清白蛋白相互作用的阐明:光谱法和计算方法
Martin Luther John,Akella Sivaramakrishna,Ravi Kanth Kamlekar
Martin Luther John
N-Acyltaurines (NATs) are endogenous neurotransmitters, structurally similar to endocannabinoids, and have anti-inflammatory and anti-proliferative effects. In response to NATs, TRP channels, TRPV1, TRPV4 and the peptide hormone, GLP-1 are ...
Long-chain cationic gemini surfactants as drug retention adjuvant on liposomes. A methodological approach with atorvastatin [0.03%]
长链阳离子双子表面活性剂作为药物滞留辅助剂在脂质体上的应用。以阿托伐他汀为研究对象的方法学探讨
Yago Radziunas-Salinas,Vicente Domínguez-Arca,Alberto Pardo et al.
Yago Radziunas-Salinas et al.
This study delves into the development and characterization of dipalmitoyl phosphatidylcholine (DPPC) liposomes incorporated with gemini surfactant (tetradecamethylene-1,14 bis(dimethyl tetradecyl ammonium bromide); 14-14-14) and atorvastat...
Effect of osmolytes on the conformational stability of Aβ(25-35): A circular dichroism analysis [0.03%]
渗透调节剂对Aβ(25-35)构象稳定性的效应:圆二色性分析
Angelo Santoro,Michela Buonocore,Anna Maria DUrsi
Angelo Santoro
Alzheimer's (AD) is a neurodegenerative disease characterized by the onset and progression of mental decline. AD aetiopathogenesis is still questioned; however, according to one of the most accredited hypotheses, the accumulation of amyloid...
Replacement of phenyl substituents at phosphorus by hexyl ones in 2-(2-hydroxyaryl)vinylphosphonium salts can tune the nature of the induced proton transport through lipid membranes [0.03%]
磷上苯基取代基被己基取代可以调节2-(2-羟基芳基)乙烯亚磷盐通过脂质膜诱导的质子传输性质
Tatyana I Rokitskaya,Ljudmila S Khailova,Anna G Strelnik et al.
Tatyana I Rokitskaya et al.
2-(2-hydroxyaryl)vinylphosphonium salts are zwitterionic protonophores previously shown to induce proton transport across lipid membranes via cyclic deprotonation and protonation of the hydroxyl group. Here, we examine the impact of the kin...
Corrigendum to "Structural analysis of the NK-lysin-derived peptide NK-2 upon interaction with bacterial membrane mimetics consisting of phosphatidylethanolamine and phosphatidylglycerol" [BBA - Biomembranes 1866 (2024) 184267] [0.03%]
“关于NK-lys衍生肽NK-2与由磷脂酰乙醇胺和磷脂酰甘油组成的细菌膜模拟物相互作用的结构分析”的勘误表[BBA - 生物膜 1866 (2024) 184267]
Jörg Andrä,Christopher Aisenbrey,U S Sudheendra et al.
Jörg Andrä et al.
Lock and key: Quest to find the most compatible membrane mimetic for studying membrane proteins in native environment [0.03%]
锁钥关系:寻找最适宜的膜模拟系统以研究天然环境下的膜蛋白
Rahul Yadav,Debarghya Pratim Gupta,Chandan Singh
Rahul Yadav
Membrane proteins play crucial roles in cellular signal transduction, molecule transport, host-pathogen interactions, and metabolic processes. However, mutations, changes in membrane properties, and environmental factors can lead to loss of...
The effect of oxidative stress on the adenosine A2A receptor activity and signalling [0.03%]
氧化应激对腺苷A2A受体活性和信号转导的影响
Idoia Company-Marín,Joseph Gunner,David Poyner et al.
Idoia Company-Marín et al.
The adenosine A2A receptor (A2AR) is a G-protein coupled receptor that has important anti-inflammatory effects in response to some agonists and consequently is considered a therapeutic target. Its activity is affected by local membrane lipi...