Fine tuning of the photosystem II major antenna mobility within the thylakoid membrane of higher plants [0.03%]
陆地植物类囊体膜中PSII主要天线蛋白复合物的精细调节机制研究
Vangelis Daskalakis,Sotiris Papadatos,Ulrich Kleinekathöfer
Vangelis Daskalakis
Depending on the amount of light, the photosystem II (PSII) antennae or Light Harvesting Complexes (LHCII) switch between two states within the thylakoid membranes of higher plants, i.e., a light-harvesting and a photoprotective mode. This ...
Nanomechanical insights: Amyloid beta oligomer-induced senescent brain endothelial cells [0.03%]
纳米机械学见解：淀粉样蛋白β低聚物诱导的衰老脑内皮细胞
Tanmay Kulkarni,Ramcharan Singh Angom,Pritam Das et al.
Tanmay Kulkarni et al.
Senescent cells accumulate in various peripheral tissues during aging and have been shown to exacerbate age-related inflammatory responses. We recently showed that exposure to neurotoxic amyloid β (Aβ1-42) oligomers can readily induce a s...
Hopanoids, like sterols, modulate dynamics, compaction, phase segregation and permeability of membranes [0.03%]
霍烷类化合物像固醇一样可调节细胞膜的动力学、紧实性、相分离和通透性
Agustín Mangiarotti,Darío M Genovese,Christoph A Naumann et al.
Agustín Mangiarotti et al.
In recent years, hopanoids, a group of pentacyclic compounds found in bacterial membranes, are in the spotlight since it was proposed that they induce order in lipid membranes in a similar way cholesterol do in eukaryotes, despite their str...
Geoffrey C Li,Eliot T C Forster-Benson,Charles R Sanders
Geoffrey C Li
Recent advances in whole genome and exome sequencing have dramatically increased the database of human gene variations. There are now enough sequenced human exomes and genomes to begin to identify gene variations that are notable because th...
Highly conserved intracellular H208 residue influences agonist selectivity in bitter taste receptor T2R14 [0.03%]
苦味受体T2R14中高度保守的胞内H208残基影响激动剂的选择性
Feroz Ahmed Shaik,Appalaraju Jaggupilli,Prashen Chelikani
Feroz Ahmed Shaik
Bitter taste receptors (T2Rs) are a specialized class of cell membrane receptors of the G protein-coupled receptor family and perform a crucial role in chemosensation. The 25 T2Rs in humans are activated by structurally diverse ligands of p...
Structure and membrane-targeting of a Bordetella pertussis effector N-terminal domain [0.03%]
百日咳博德特氏菌效应物N端结构域的结构及其靶向膜结构域
Adi Yahalom,Geula Davidov,Sofiya Kolusheva et al.
Adi Yahalom et al.
BteA, a 69-kDa cytotoxic protein, is a type III secretion system (T3SS) effector in the classical Bordetella, the etiological agents of pertussis and related mammalian respiratory diseases. Like other cytotoxicity-mediating effectors, BteA ...
Structural characterization and biological activity of Crabrolin peptide isoforms with different positive charge [0.03%]
不同正电荷的Crabrolin多肽异构体的结构表征及其生物活性研究
M Aschi,N Perini,N Bouchemal et al.
M Aschi et al.
The search of antimicrobial peptides (AMP) as candidates for the development of antibiotics is an active research field. In this paper we investigated the role of charged residues in antimicrobial activity by using as a template the previou...
Cholesterol alters the inhibitory efficiency of peptide-based membrane fusion inhibitor [0.03%]
胆固醇改变了基于肽的膜融合抑制剂的抑制效率
Gourab Prasad Pattnaik,Hirak Chakraborty
Gourab Prasad Pattnaik
The membrane composition modulates membrane fusion by altering membrane physical properties and the structure, organization and dynamics of fusion proteins and peptides. The journey of developing peptide-based viral fusion inhibitors is oft...
Measuring molecular order for lipid membrane phase studies: Linear relationship between Laurdan generalized polarization and deuterium NMR order parameter [0.03%]
用于脂质膜相研究的分子有序性测定方法：Laurdan广义极化与氘NMR顺序参数之间的线性关系
Sherry See Wai Leung,Jonathan Brewer,Luis A Bagatolli et al.
Sherry See Wai Leung et al.
Two dimensional phase separation in lipid membranes and cell membranes is of interest to biology because of the idea of membrane rafts - compositionally heterogeneous liquid crystal domains with cellular functions. Few quantitative tools ex...
Tea Mužić,Fatma Tounsi,Søren B Madsen et al.
Tea Mužić et al.
We investigated melting transitions in native biological membranes containing their membrane proteins. The membranes originated from E. coli, B. subtilis, lung surfactant and nerve tissue from the spinal cord of several mammals. For some pr...