Regulation of actin dynamics by phosphoinositides: Focus on postsynaptic plasticity [0.03%]
磷脂肌醇调控肌动蛋白动力学在突触后可塑性中的作用
Joseph P Albanesi,Jen Liou,Jui-Yu-Yeh et al.
Joseph P Albanesi et al.
Phosphoinositides, most prominently phosphatidylinositol (4,5)-bisphosphate and phosphatidylinositol (3,4,5)-trisphosphate, regulate the activities of a wide range of proteins that control the polymerization, depolymerization, and branching...
Nuclear phosphoinositides: An exploration into their regulation, roles and physico-chemical environment [0.03%]
核磷脂肌醇磷酸盐：其调控、功能及理化环境的研究
Charlotte L Collier,Palita Udomjarumanee,Lee Morgan et al.
Charlotte L Collier et al.
Polyphosphoinositides are phospholipids consisting of a diacylglycerol backbone linked to an inositol headgroup that can be phosphorylated at three positions, generating seven distinct lipid species. Their levels are tightly regulated by co...
Lipidomic analysis of phospholipids and transcript expression of lipid metabolism genes in the liver and muscle of Atlantic salmon fed microbial oil and canola oil [0.03%]
饲喂微生物油脂和菜籽油的大西洋鲑鱼肝脏和肌肉磷脂的脂质组分析及脂质代谢基因转录表达量测定
Mohamed Emam,JuDong Yeo,Stefanie M Colombo et al.
Mohamed Emam et al.
The increasing global demand for aquaculture products requires sustainable fish feed strategies. This study investigated how replacing fish oil with microbial oil (MO) and canola oil (CO) combinations affects lipid metabolism and gene expre...
Heat therapy attenuates hepatic lipid accumulation via CSAD-driven metabolic reprogramming of fatty acid oxidation [0.03%]
热疗通过CSAD介导的脂肪酸氧化代谢重编程减轻肝脏脂质积累
Ang Li,Yaru Dai,Yijun Luo et al.
Ang Li et al.
Objective: Non-alcoholic fatty liver disease (NAFLD) represents a significant global health challenge, predominantly managed through non-pharmacological interventions. Heat therapy (HT) has been shown to effectively reduc...
Substituents of the polysaccharide region of LPS in Legionella pneumophila sg1 modulate interactions with host cells [0.03%]
Legionella pneumophila第1血清群中LPS多糖区的取代基调节与宿主细胞的作用
Bożena Kowalczyk,Agnieszka Szuster-Ciesielska,Zbigniew Kaczyński et al.
Bożena Kowalczyk et al.
Legionella pneumophila is a Gram-negative bacterium commonly found in natural freshwater reservoirs, where it exists as an intracellular parasite of cohabiting protozoa, primarily of the genus Acanthamoeba. Inhalation of aerosol contaminate...
Yeast phosphatidylinositol transfer protein Pdr16 supports azole resistance independently of lipid droplets [0.03%]
酿酒酵母磷脂酰肌醇转移蛋白Pdr16可独立于脂滴支持唑类抗性
Lucia Pokorná,Dana Tahotná,Rebeka Rusnáková et al.
Lucia Pokorná et al.
Gm15441 improves adipogenesis and insulin sensitivity by TXNIP regulation in white adipose tissue [0.03%]
GM15441通过调节白色脂肪组织中的TXNIP改善脂肪细胞生成和胰岛素敏感性
Yinze Shi,Liying Huang,Xueyang Yang et al.
Yinze Shi et al.
Gm15441, a long non-coding RNA antisense to thioredoxin interacting protein (TXNIP) mRNA, exhibits undefined roles in adipogenesis and insulin resistance. This study aimed to explore its functions and mechanisms in white adipose tissue (WAT...
The endocannabinoid-derived prostaglandin glycerol esters and prostaglandin ethanolamides modulate intestinal epithelial hallmarks of colitis [0.03%]
大麻素衍生的前列腺甘油酯和前列腺乙醇胺调节结肠炎相关肠上皮标志物
Joan Bestard-Escalas,Olivia Sasportes,Hafsa Ameraoui et al.
Joan Bestard-Escalas et al.
Inflammatory bowel diseases (IBD) are chronic inflammatory disorders of the gastrointestinal tract with a high impact on patients' quality of life. The endocannabinoids 2-arachidonoylglycerol (2-AG) and N-arachidonoylethanolamine (AEA) are ...
Valproate causes inositol depletion in yeast by decreasing levels of phosphatidic acid and increasing Opi1-mediated repression of INO1 expression [0.03%]
丙戊酸通过降低磷脂酸水平和增加Opi1介导的INO1表达抑制作用在酵母中诱导肌醇含量下降
Chisom J Onu,Michael Adu,Gil-Soo Han et al.
Chisom J Onu et al.
Valproic acid (VPA) is a widely prescribed mood stabilizer used in the pharmacological management of bipolar disorder (BD), a psychiatric illness that affects 2% of the world's population. Although VPA has been in use for four decades, the ...
Neuroprotective effect of berberine-loaded niosomes against brain injury in dyslipidemic rats: The interplay between oxidative stress, mitochondrial dysfunction and apoptotic signals [0.03%]
小檗碱纳米囊泡对高血脂大鼠脑损伤的神经保护作用：氧化应激、线粒体功能障碍和凋亡信号之间的相互作用
Mohamed Fouad Mansour,Amany Behairy,Tarek Khamis et al.
Mohamed Fouad Mansour et al.
Dyslipidemia is a major risk factor for the development of atherosclerosis, cardiovascular diseases, and brain injury. Berberine (BER), a type of isoquinoline alkaloid, has the potential to enhance mitochondrial performance owing to its rem...