Corrigendum to "Negative modulation of mitochondrial oxidative phosphorylation by epigallocatechin-3 gallate leads to growth arrest and apoptosis in human malignant pleural mesothelioma cells" [Biochim. Biophys. Acta (BBA) Mol. Basis Dis. 1832(12) (2013) 2085-2096] [0.03%]
关于“表没食子儿茶素-3- gallate对线粒体氧化磷酸化的负调节导致人恶性胸膜间皮细胞生长停滞和凋亡”一文的勘误[Biochim. Biophys. Acta (BBA) Mol. Basis Dis. 1832(12)(2013)2085-2096]
Daniela Valenti,Lidia de Bari,Gabriella Arcangela Manente et al.
Daniela Valenti et al.
Atractylenolide I ameliorates acute-on-chronic liver failure (ACLF) by promoting autophagy and preserving mitochondrial function through mTOR inhibition [0.03%]
苍术素I通过抑制mTOR促进自噬和保护线粒体功能从而改善急性-on-慢性肝衰竭(ACLF)
Dan Tang,Fei Tuo,Jie Chen et al.
Dan Tang et al.
Acute-on-chronic liver failure (ACLF) is a severe liver syndrome marked by systemic inflammation and high mortality, often complicated by autophagy impairment and mitochondrial dysfunction. This study investigates atractylenolide I (AT-1), ...
Unveiling the link between insulin-like growth factor 1 (IGF-1) and fatty liver progression: From bench to bedside [0.03%]
揭秘胰岛素样生长因子1(IGF-1)与脂肪肝进展之间的联系:从实验室到临床
Kornkanok Srimanus,Alisara Damrongmanee,Nuthapong Ukarapol et al.
Kornkanok Srimanus et al.
The prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD) has been rising, but the pathogenesis remains elusive, and effective treatments are limited. Insulin growth factor-1 (IGF-1), part of the somatotropic pathwa...
Extracellular histone H3 induces METosis in acute liver failure by regulating the NRF2/HO-1/NQO1 pathway-mediated oxidative stress [0.03%]
胞外组蛋白H3通过调节NRF2/HO-1/NQO1途径介导的氧化应激诱导急性肝衰竭中的METosis
Xiaoya Zhang,Jin Guo,Danmei Zhang et al.
Xiaoya Zhang et al.
Acute liver failure (ALF) is a life-threatening condition marked by extensive hepatocyte death and the subsequent release of damage-associated molecular patterns (DAMPs), notably extracellular histone H3, which contributes to severe complic...
High-oxalate diet-induced kidney injury impairs AVF remodeling via hypertension, endothelial damage, and immune activation [0.03%]
高草酸盐饮食引起的肾损伤通过高血压、内皮细胞损伤和免疫激活影响动静脉瘘重塑
E P de Winter,N Kruit,K van Dijk et al.
E P de Winter et al.
Background: Arteriovenous fistulas (AVF) are the preferred vascular access for hemodialysis, however patency rates remain low. Animal AVF models are essential for uncovering mechanisms of AVF remodeling. Yet most lack coe...
BIRC3 and NOC2L synergistically promote P53 acetylation to accelerate necroptosis in sepsis-associated acute kidney injury [0.03%]
BIRC3和NOC2L通过协同促进P53乙酰化在脓毒症相关急性肾损伤中加速坏死性凋亡
Xiaotong Ma,Yuchen Wang,Ruxue Diao et al.
Xiaotong Ma et al.
Sepsis-associated acute kidney injury (SA-AKI), defined as AKI occurring within 7 days after the onset of sepsis, is more common in critically ill patients and is strongly associated with poor prognosis. To investigate the relationship betw...
Mitochondrial complex-derived ROS induces lysosomal dysfunction and impairs autophagic flux in human cells carrying the APOE4 allele [0.03%]
APOE4等位基因携带者的人类细胞中线粒体复合物来源的ROS引起溶酶体功能障碍并损害自噬流
Sandra A Niño,Oskar Barrios-Camus,Eduardo Silva-Pavez et al.
Sandra A Niño et al.
The APOE4 allele is the strongest genetic risk factor for sporadic Alzheimer's disease (sAD), yet its cell-autonomous effects remain poorly understood. While young, asymptomatic APOE4 carriers exhibit abnormal brain metabolism, the mechanis...
Corrigendum to "Accumulation of neutral lipids in dystrophic neurites surrounding amyloid plaques in Alzheimer's disease" [2024 Apr;1870(4):167086.] [0.03%]
“阿尔茨海默病淀粉样斑块周围 dystrophic 神经元突起中中性脂质的积累”一文的勘误(卷 1870,4 期,2024 年 4 月,167086)
Hao Huang,Md Golam Sharoar,Joseph Pathoulas et al.
Hao Huang et al.
PFKFB3-driven glycolysis in endothelial cells activates RhoA/ROCK1 to promote pulmonary vascular leakage in heatstroke [0.03%]
热射病中内皮细胞依赖的PFKFB3促糖酵解激活RhoA/ROCK1促进肺血管渗漏
Chengjia Ding,Ping Huang,Jing Tuo et al.
Chengjia Ding et al.
Background: Endothelial barrier dysfunction induced by heatstroke contributes to acute lung injury; however, the underlying metabolic mechanisms remain unclear. The glycolytic regulator PFKFB3 is known to fuel inflammatio...
The isoflavone metabolites, O-desmethylangolensin and (S)-equol, relax isolated arteries ex vivo and decrease arterial blood pressure in vivo [0.03%]
异黄酮代谢产物O-脱甲基角豆素和(S)- EQUIOL对离体动脉具有松弛作用并能降低活体血压
Thomas Migkos,Jana Pourová,Iveta Nejmanova et al.
Thomas Migkos et al.
Dietary isoflavones are suggested to have positive cardiovascular effects. Their intestinal absorption is low, but they undergo extensive gastrointestinal metabolism by gut bacteria, resulting in metabolites with higher bioavailability. How...