Long non-coding RNAs and nuclear factor-κB crosstalk in cancer and other human diseases [0.03%]
长非编码RNA与核因子-κB在癌症及其他人类疾病中的相互作用
Subash C Gupta,Nikee Awasthee,Vipin Rai et al.
Subash C Gupta et al.
The regulation of the pleiotropic transcription factor, nuclear factor-κB (NF-κB) by miRNAs and proteins is extensively studied. More recently, the NF-κB signaling was also reported to be regulated by several long non-coding RNAs (lncRNA...
Functional analysis of deubiquitylating enzymes in tumorigenesis and development [0.03%]
去泛素化酶在肿瘤发生发展中的功能研究
Ji Cheng,Jianping Guo,Brian J North et al.
Ji Cheng et al.
Deubiquitylating enzymes (DUBs) are proteases that remove the ubiquitin moiety from ubiquitylated substrates to antagonize the modification mediated by E3 ubiquitin ligases. Currently, DUBs have been found to play critical roles in the regu...
The tumor immune microenvironment in gastroenteropancreatic neuroendocrine neoplasms [0.03%]
胃肠胰神经内分泌肿瘤的肿瘤免疫微环境
Wu-Hu Zhang,Wen-Quan Wang,He-Li Gao et al.
Wu-Hu Zhang et al.
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are a group of rare tumors that are increasing in prevalence. The complex tumor immune microenvironment (TIME) plays an important role in tumor development and the response to immun...
Svetlana N Aleksakhina,Aniruddh Kashyap,Evgeny N Imyanitov
Svetlana N Aleksakhina
Systemic therapy often results in the reduction of tumor size but rarely succeeds in eradicating all cancer cells. Drug efflux, persistence of cancer stem cells (CSCs), epithelial-mesenchymal transition (EMT) and down-regulation of apoptosi...
Cell death in photodynamic therapy: From oxidative stress to anti-tumor immunity [0.03%]
光动力疗法中的细胞死亡：从氧化压力到抗肿瘤免疫反应
Claire Donohoe,Mathias O Senge,Luís G Arnaut et al.
Claire Donohoe et al.
Photodynamic therapy is a promising approach for cancer treatment that relies on the administration of a photosensitizer followed by tumor illumination. The generated oxidative stress may activate multiple mechanisms of cell death which are...
From squamous intraepithelial lesions to cervical cancer: Circulating microRNAs as potential biomarkers in cervical carcinogenesis [0.03%]
从鳞状上皮内病变到宫颈癌：循环microRNA作为宫颈癌变潜在生物标志物的研究
Fernanda Costa Brandão Berti,Amanda Salviano-Silva,Helen Cristina Beckert et al.
Fernanda Costa Brandão Berti et al.
Despite the essential role of Human Papillomavirus (HPV) in cervical carcinogenesis, other factors are required for cancer establishment, like miRNAs. Such molecules present a complex biogenesis, being diversely distributed across tissues a...
From squamous intraepithelial lesions to cervical cancer: Circulating microRNAs as potential biomarkers in cervical carcinogenesis [0.03%]
从鳞状上皮内病变到宫颈癌：循环microRNA作为宫颈癌变潜在生物标志物的研究
Fernanda Costa Brandão Berti,Amanda Salviano-Silva,Helen Cristina Beckert et al.
Fernanda Costa Brandão Berti et al.
Despite the essential role of Human Papillomavirus (HPV) in cervical carcinogenesis, other factors are required for cancer establishment, like miRNAs. Such molecules present a complex biogenesis, being diversely distributed across tissues a...
Karla Vinasco,Hazel M Mitchell,Nadeem O Kaakoush et al.
Karla Vinasco et al.
While Helicobacter pylori is a fundamental risk factor, gastric cancer (GC) aetiology involves combined effects of microbial (both H. pylori and non-H. pylori), host and environmental factors. Significant differences exist between the gastr...
Karla Vinasco,Hazel M Mitchell,Nadeem O Kaakoush et al.
Karla Vinasco et al.
While Helicobacter pylori is a fundamental risk factor, gastric cancer (GC) aetiology involves combined effects of microbial (both H. pylori and non-H. pylori), host and environmental factors. Significant differences exist between the gastr...
Matthew John Wakefield,Ksenija Nesic,Olga Kondrashova et al.
Matthew John Wakefield et al.