Unraveling the role of mucins and gut microbiota in gastrointestinal cancers chemoresistance [0.03%]
粘蛋白和肠道微生物群在胃肠道癌症化学抗性中的作用机制解析
A M Vrinda,Muthusamy Thangaraju,S Asha Nair et al.
A M Vrinda et al.
The interaction between heavily glycosylated mucin proteins in the mucus layer, gut microbes, and gastrointestinal (GI) tract cancers has been extensively studied to improve treatment outcomes and survival rates in cancer patients. Colorect...
Corrigendum to "Unveiling the TGF-β/Smad signaling in renal carcinoma progression: Prognostic and therapeutic insights" [Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, Volume 1880, Issue 4, (2025) / 189372] [0.03%]
关于“揭开TGF-β/Smad信号通路在肾癌进展中的作用：预后和治疗见解”的勘误表[Biochimica et Biophysica Acta (BBA)-Reviews on Cancer，第1880卷，第4期,(2025)/ 189372]
Vânia Dias,Ângela Alves,Rui Medeiros et al.
Vânia Dias et al.
Targeting cu metabolism as a potential therapeutic strategy for pulmonary fibrosis [0.03%]
靶向铜代谢作为潜在的肺纤维化治疗策略
Bo Li,Min Zhang,Jing Cai et al.
Bo Li et al.
Cuproptosis, a recently identified form of programmed cell death driven by copper (Cu) ions, has gained attention owing to its involvement in metabolic disorders and degenerative conditions. Pulmonary fibrosis, characterized by abnormal ext...
EV-mediated asymmetrical crosstalk between CAFs and cancer cells in the tumor microenvironment [0.03%]
肿瘤微环境中的癌细胞和CAF之间的EV介导的不对称串扰
Alice Santi,Annalisa Moccia,Anna Caselli et al.
Alice Santi et al.
Tumor is a complex tissue composed of both genetically transformed cancer cells and the cells of the tumor microenvironment, including connective cells, immune cells, and endothelial cells that actively contribute to the maintenance of the ...
Gut microbiota as a mediator of cancer development and management: From colitis to colitis-associated dysplasia and carcinoma [0.03%]
肠道菌群在癌症发生和发展中的作用：从结肠炎到相关性上皮内瘤变和癌变
Wanyue Dan,Cenxi Xiong,Guanzhou Zhou et al.
Wanyue Dan et al.
Colitis-associated colorectal cancer (CAC) develops as a result of prolonged colitis in patients with inflammatory bowel disease. In recent years, the role of the gut microbiota in colitis-associated colorectal carcinogenesis has begun to b...
Targeting KRAS in colorectal cancer immunotherapy: rationale, challenges and future directions [0.03%]
KRAS在结直肠癌免疫治疗中的作用：理由、挑战和未来方向
Gongmin Zhu,Lijiao Pei,Di Ye et al.
Gongmin Zhu et al.
Kirsten rat sarcoma (KRAS) is frequently mutated in colorectal cancer (CRC). In recent years, mutant KRAS has shed its "undruggable" label, with two clinically approved inhibitors now available. Besides aberrantly activating intrinsic tumor...
Shubhraneel Saha,Anjali Bhat,Samiksha Kukal et al.
Shubhraneel Saha et al.
Glioblastoma multiforme (GBM) is a highly aggressive brain cancer marked by aggressive growth and therapeutic resistance. A growing body of research highlights substantial spatial heterogeneity within GBM tumors as a critical factor contrib...
Combination therapy in cancer: The potential of tetrandrine as a polytherapy for acute myeloid leukemia [0.03%]
四氢藤素联合化疗治疗急性髓系白血病的潜力研究
Daniel L Barry,Anoop K Enjeti,Lisa F Lincz et al.
Daniel L Barry et al.
Acute Myeloid Leukemia (AML) is the most common form of leukemia diagnosed in adults with the lowest survival rates. It is a heterogeneous disease and incidence rates increase yearly, with the overall survival of AML patients remaining low....
Raquel Monteiro de Barros Lemos,Marina Chianello Nicolau Fagundes,Ana Luiza Tardem Maciel et al.
Raquel Monteiro de Barros Lemos et al.
Polycomb Repressive Complex 2 (PRC2) is a key epigenetic regulator involved in T-cell biology and leukemogenesis. While traditionally known for gene silencing via H3K27me3, recent studies reveal roles in T-cell differentiation, thymocyte ma...
The VEGF/VEGFR2 system in ovarian cancer: From functional to pharmacological significance [0.03%]
血管内皮生长因子/血管内皮生长因子受体2系统在卵巢癌中的功能及药理学意义研究进展
Elisabetta Grillo,Chiara Romani,Victoria M Ettorre et al.
Elisabetta Grillo et al.
The vascular endothelial growth factor receptor 2 (VEGFR2) is a tyrosine kinase receptor regulating a variety of biological processes, including embryonic development, angiogenesis, tissue homeostasis and cancer. VEGFR2 is activated by cano...