Coagulopathy in acute promyelocytic leukaemia: Can we better predict and prevent catastrophic bleeding? [0.03%]
急性早幼粒细胞白血病的凝血障碍：能否更好地预测和预防灾难性出血？
Dawn Swan,Takayuki Ikezoe,Anna Falanga et al.
Dawn Swan et al.
Acute promyelocytic leukaemia is a distinct subset of acute myeloid leukaemia characterised by severe coagulopathy. Overall, patient prognosis is excellent, with outcomes revolutionized by the advent of all-trans retinoic acid and arsenic t...
Novel germline genetic variants associated with venous thrombo-embolism (VTE) and arterial thrombo-embolism (ATE) risk in patients with ALK and ROS1 fusion non-small cell lung cancer (NSCLC) [0.03%]
ALK和ROS1重排非小细胞肺癌患者遗传性基因变异与静脉血栓栓塞和动脉血栓栓塞风险相关性研究
S Khan,B Jimenez Munarriz,K Hueniken et al.
S Khan et al.
Rivaroxaban for pediatric venous thromboembolism in routine clinical practice: Effectiveness and safety from a real-world cohort [0.03%]
来自真实世界队列的儿科常规临床实践中的静脉血栓栓塞症使用瑞洛-xl的安全性和有效性研究
Yunyun Wei,Jia Li,Yumeng Jia et al.
Yunyun Wei et al.
Background: The incidence of pediatric venous thromboembolism (VTE) has been increasing in recent years. Due to the unique hemostatic characteristics of children, thrombi are often difficult to resolve once formed and may...
Col003 attenuates sepsis-associated coagulation dysfunction in mice in association with reduced platelet activation and NET formation [0.03%]
COL003通过减少血小板活化和中性粒细胞胞外陷阱形成来缓解小鼠脓毒症相关凝血功能障碍
Xinyang Zhao,Ruoqing Lin,Ruixuan Lin et al.
Xinyang Zhao et al.
Background: Coagulation dysfunction is a major contributor to the increased mortality associated with sepsis (Levi et al., 2013; Gando et al., 2019 [1,2]), in which platelet activation, neutrophil activation, and neutroph...
Analysis of the whole transcriptome of deep vein thrombosis and immune-metabolic characteristics reveals the lipid metabolism-NETosis coupling axis [0.03%]
全转录组分析结合免疫代谢特征揭示深静脉血栓的脂代谢-NETosis偶联轴
Ming Xue,Zhongqing Chen,Xuexun Zheng et al.
Ming Xue et al.
Background: Deep vein thrombosis (DVT) is a common venous thrombotic disease associated with substantial morbidity and mortality. Its onset and progression are closely related to coagulation abnormalities and are also pro...
Comparing perioperative heparin bridging strategies in mechanical heart valve patients undergoing surgery: A systematic review and Bayesian meta-analysis [0.03%]
机械瓣膜病患者手术期间使用肝素桥接策略的系统评价和bayesian meta分析
Pedro Gomes Batista,Marcela Vasconcelos Montenegro,Giulia Caldeira Gaelzer et al.
Pedro Gomes Batista et al.
Introduction: Perioperative heparin bridging in surgical mechanical heart valve (MHV) patients aims to prevent thromboembolism but risks bleeding. Addressing a lack of comparative data, this study synthesizes current lite...
Direct oral anticoagulants during lactation: A landscape defined by absence [0.03%]
哺乳期使用的直接口服抗凝药：一个由空白定义的领域
C Dini Khairani,Azita H Talasaz
C Dini Khairani
Current practices in the use and monitoring of intravenous unfractionated heparin infusions - A cross-sectional UK survey [0.03%]
英国现行输液用未分级肝素使用和监测情况——一项横断面调查研究
Jignesh P Patel,Rosalind Byrne,Nathan Hutchinson-Jones et al.
Jignesh P Patel et al.
APTTO: a clot waveform analysis-based algorithm for diagnostic triage of prolonged activated partial thromboplastin time [0.03%]
基于凝血波形分析的延长活化部分凝血活酶时间诊断分流算法(APTTO)
Diego Velasco-Rodríguez,Nuria Revilla,Ignacio Mahíllo-Fernández et al.
Diego Velasco-Rodríguez et al.
Background: Prolonged activated partial thromboplastin time (APTT) is a common laboratory finding that frequently triggers extensive diagnostic testing and may delay clinical decision-making, particularly in the preoperat...
Bleeding-related quality of life in older adults: Psychometric evaluation of the HEmorrhage Life Impact indeX (HELIX) [0.03%]
老年人大出血相关生活质量的评估：HEmorrhage Life Impact Index(HELIX) 的心理测量学属性分析
Anna L Parks,Gregory J Stoddard,Amy M Cizik et al.
Anna L Parks et al.
Background: Older adults treated with anticoagulants for atrial fibrillation (AF) or venous thromboembolism (VTE) face heightened bleeding risk, which can affect physical, emotional and social wellbeing and function. Exis...