Refining the AOP for retinoid-induced teratogenicity: Insights into RAR/RXR overactivation and RXR cross-talk with retinoic acid and thyroid hormone signaling [0.03%]
视黄酸致畸的AOP优化：视黄酸受体/-retinoid X受体过度激活及retinoid X受核与甲状腺素信号串扰的新见解
Audrey Phan,Elise Pesce,Lisa Baumann et al.
Audrey Phan et al.
Retinoic acid (RA), a vitamin A metabolite, plays a crucial and evolutionarily conserved role in vertebrate development. Chemical disruption of retinoid signaling can severely affect organisms; yet, despite its teratogenicity and pathway in...
Molecular responses to pollution stress in glass eels (Anguilla anguilla): Gene expression changes associated with varying contamination levels and temperature across estuaries [0.03%]
玻璃鳗鱼（Anguilla anguilla）对污染压力的分子反应：与不同污染水平和跨河口温度变化相关的基因表达变化
Alvaro Gutierrez-Rodriguez,Claudia Nuñez-Moyano,Lucía Rivas-Iglesias et al.
Alvaro Gutierrez-Rodriguez et al.
Understanding the effects of global change is crucial to aid in the conservation of critically endangered species such as the European eel (Anguilla anguilla). Emerging pollutants (microplastics) and legacy ones such as heavy metals, as wel...
Domoic acid production by a Pseudo-nitzschia australis strain under zinc and copper exposure [0.03%]
锌和铜胁迫下Pseudo-nitzschia australis藻株产生石房蛤毒素的研究
Marie Bassez,Hélène Hégaret,Jean-François Maguer et al.
Marie Bassez et al.
The diatom species Pseudo-nitzschia australis can produce domoic acid (DA), a neurotoxin- responsible for amnesic shellfish poisoning. Copper (Cu) and zinc (Zn) are essential trace metals for marine phytoplankton, but they can become either...
Interactions between cyanobacteria and emerging contaminants in aqueous environments [0.03%]
蓝藻与水环境中新兴污染物的相互作用
Yichen Yang,Xiaohan Zhang,Lingshen Tan et al.
Yichen Yang et al.
Cyanobacteria, prevalent in aquatic environments, are key contributors to the Earth's primary productivity and have historically transformed the planet's surface from anaerobic to aerobic conditions. However, due to improper disposal, a lar...
Biochemical and molecular stress responses to enrofloxacin in Mytilus galloprovincialis: transient or lasting effects? [0.03%]
鸭嘴海绵贻贝中华绒螯蟹稚蟹鳃组织抗氧化酶对恩诺沙星的响应分析
J Giannessi,C Pretti,V Meucci et al.
J Giannessi et al.
Antibiotic contamination is an emerging threat in marine environments due to its potential to alter key physiological processes in non-target organisms. Among veterinary antibiotics, enrofloxacin (ENR), a widely used fluoroquinolone, is fre...
Endocrine disruptive effects and mechanisms of isothiazolinone analogs in marine medaka (Oryzias melastigma) embryos and H295R cells [0.03%]
异噻唑啉酮类衍生物的内分泌干扰效应及其机制：以鱼类胚胎和体外细胞为模型的研究
Jiali Li,Lizhu Tang,Jing Li et al.
Jiali Li et al.
The application of isothiazolinones as antimicrobial agents has caused prevalent pollution of marine environment. However, the developmental toxicity and endocrine disrupting effects of different isothiazolinone analogs to marine organisms ...
Marine ecotoxicity evaluation of 10 per- and poly-fluoroalkyl acids using three USEPA short-term chronic bioassays [0.03%]
采用三种美国环保局短期慢性生物测定法评价10种全氟和多氟烷基酸的海洋生态毒性
Nicholas T Hayman,Zacharias Pandelides,Josiah Discar et al.
Nicholas T Hayman et al.
Effects data for per- and poly-fluoroalkyl substances (PFAS) for marine aquatic life are lacking, limiting the assessment of site-specific ecological risks in marine ecosystems and development of marine water quality criteria. In this study...
Subchronic 2,6-dichloro-1,4-benzoquinone exposure induced dose-dependent cardiac functional failure via cytoskeletal remodeling in zebrafish cardiac tissue [0.03%]
剂量依赖性2,6-二氯-1,4-苯醌暴露通过斑马鱼心脏组织的细胞骨架重塑诱导心功能障碍
Xue Yang,Qiwei Zhang,Lihua Yang
Xue Yang
The subchronic cardiotoxicity of 2,6-dichloro-1,4-benzoquinone (2,6-DCBQ), an unregulated disinfection byproduct with high environmental detection rates, remains poorly characterized. Using integrated multi-omics (transcriptomics, proteomic...
Mixture toxicity of perfluoroalkyl substances on the aquatic invertebrate Gammarus roeselii [0.03%]
全氟化合物对水生无脊椎动物Gammarus roeselii的混合毒性
Erwin J J Kalis,Johannes W Zander,Juergen Geist et al.
Erwin J J Kalis et al.
In recent years, PFAS (per- and polyfluoroalkyl substances) have been the focus of increasing attention due to their persistent, bioaccumulative and toxic properties. Given the variety of PFAS compounds, and potential interacting effects on...
Mitigative effects of Vitamin C on deltamethrin-induced acute toxicity in crucian carp by modulating the AhR/Nrf2 signaling pathways [0.03%]
维生素C通过调节AhR/Nrf2信号途径对克氏原螯虾中高效氯氰菊酯诱导的急性毒性的影响研究
Hao Wu,Jinwei Gao,Dong Liu et al.
Hao Wu et al.
In recent years, deltamethrin (DEL) pollution poses a significant threat to aquaculture; however, the protective role of vitamin C (VC) against acute toxicity in crucian carp has not been well understood. This study provides compelling evid...