Characterizing tissue-specific accumulation dynamics and assessing healthy risk of organic insecticides in sea cucumbers based on a multicompartmental toxicokinetic model [0.03%]
基于多室毒物动力学模型的有机杀虫剂的风险评估及仿生拾取动力学研究
Xiao Cong,Tongtong Jiang,Lei Wang et al.
Xiao Cong et al.
Organophosphate and organochlorine insecticides have attracted attention owing to their chronic toxicity, environmental persistence, and bioaccumulation potential. Their excessive and illegal use has led to food safety risks in sea cucumber...
Metal handling in the liver of the field collected northern pike (Esox lucius): indication of multiple metallothionein isoforms [0.03%]
北方梭鱼(食蚊鱼类)肝脏中金属处理：多种金属硫蛋白同工型的指示标志
Zrinka Dragun,Zoran Kiralj,Dušica Ivanković et al.
Zrinka Dragun et al.
Metallothioneins (MTs), cysteine-rich low-molecular-mass metal-binding proteins with a role in metal homeostasis and detoxification, often occur in several isoforms, that slightly differ among species/organs, but can have notably different ...
Acidification exacerbates lead-induced toxicity in crabs: Oxidative stress, microbiota disruption, and dietary intervention [0.03%]
酸化加剧了铅对螃蟹毒性的效应：氧化应激、微生物群紊乱和饮食干预
Peng Zhao,Meng Ji,Zhigang Yang et al.
Peng Zhao et al.
The combined effects of water acidification and lead (Pb) pollution have become a significant ecological risk factor for freshwater aquaculture systems. In this study, we systematically evaluated the effects of acidification and Pb exposure...
Neurobehavioral and molecular responses of the endemic barbel Carasobarbus fritschii to pyriproxyfen, salinity, and thermal stress [0.03%]
新型杀虫剂吡丙醚及盐度、温度变化对土著鱼类黄斑唇鳞铲颌鱼的行为和分子响应的影响
Abdelilah Ahnich,Mohamed Naimi,Oualid Abboussi et al.
Abdelilah Ahnich et al.
Freshwater ecosystems in arid and semi-arid regions are increasingly threatened by multiple anthropogenic stressors and climate-driven temperature rise. Understanding how these stressors affect native fish species is critical for prioritizi...
Maternal effects on offspring population dynamics in Brachionus calyciflorus differ between exposure to non-toxic Microcystis aeruginosa and MC-LR [0.03%]
暴露于蓝藻和微囊藻毒素-MC-LR下母体对栅藻属钙壳臂尾轮虫子代种群动态的影响不同
Jia Na,Cuijuan Niu
Jia Na
Maternal effects can shape offspring phenotypes related to fitness and thus play an important role in regulating population dynamics. The inhibitory effect of bloom algae Microcystis aeruginosa (particularly toxin-producing strains) on roti...
Chronic exposure to environmentally relevant Bisphenol F induces hepatic injury and inflammation in Zebrafish [0.03%]
环境相关水平的四溴双酚F慢性暴露导致斑马鱼肝损伤及炎症反应
Yuehong Shen,Dingyu Zhou,Tong Wei et al.
Yuehong Shen et al.
Bisphenol F (BPF), a major substitute for bisphenol A (BPA), has raised safety concerns. To evaluate its hepatotoxicity at environmentally relevant concentrations, zebrafish larvae (5-day exposure) and adults (120-day exposure) were exposed...
Genotoxic effects of 6PPD-quinone on juvenile European seabass (Dicentrarchus labrax): Impacts on DNA replication fidelity and oxidative DNA damage [0.03%]
6PPD醌对幼鱼欧洲海鲈(_dicentrarchus Labrax_)的致突变作用：对DNA复制保真度和氧化性DNA损伤的影响
Haitham G Abo-Al-Ela,Rasha A Al Wakeel,Abeer Gamal Zaki et al.
Haitham G Abo-Al-Ela et al.
Juvenile European seabass (Dicentrarchus labrax) were exposed to environmentally relevant 6PPD-quinone (2.85 µg/L) for five days to evaluate transcriptional, oxidative, and antioxidant responses and histopathology. The liver showed the str...
Ternary lithium-ion battery cathode material NCM523 impairs planarian locomotor activity, growth and regeneration [0.03%]
三元锂离子电池正极材料NCM523对涡虫运动、生长和再生的影响
Zhicheng Chen,Yufan Deng,Ying Li et al.
Zhicheng Chen et al.
The expanding use of ternary lithium-ion batteries has raised growing concerns about their potential ecological and health risks in recent years. This study aimed to investigate the effects and underlying mechanisms of the ternary lithium-i...
BPA impairs the intestinal health of Gobiocypris rarus by disrupting gut microbiota, altering fatty acid metabolism, and affecting mucus secretion [0.03%]
双酚A通过扰乱肠道微生物平衡、改变脂肪酸代谢和影响粘液分泌而损害扁牙 carp的肠道健康
Jun Wang,Zhengjia Wei,Xinrui Li et al.
Jun Wang et al.
Bisphenol A (BPA) is an endocrine-disrupting chemical that is widely present in aquatic environments. Much research has confirmed that BPA exerts certain toxic effects on the reproduction and development of aquatic organisms. However, curre...
Time-dependent biphasic dysregulation of autophagy and innate immunity underlies polystyrene microplastics-induced hepatotoxicity in Nile tilapia [0.03%]
尼罗罗非鱼体内聚苯乙烯微塑料引起肝毒性的自噬和先天免疫的双向失调机制
Feilong Wang,Xiaomeng Guo,Na Guo et al.
Feilong Wang et al.
The immunotoxicity of microplastic pollution in aquatic species is an issue of growing concern. However, the time course and mechanistic crosstalk underlying microplastic-induced hepatic injury remain poorly defined. This study examined the...