Exosome-related lactylation gene signature defines diagnostic biomarkers of periodontitis through integrative bulk and single-cell transcriptomics [0.03%]
基于整合的批量和单细胞转录组学的外泌体相关乳酰化基因特征定义了牙周炎的诊断生物标志物
Xueyi Liang,Runxi Fu,Xiaochuan Chen
Xueyi Liang
Background: Exosomes and lactylation modification have been increasingly recognized as key regulators of diseases, yet their integrative role in periodontitis remains unclear. No diagnostic model based on exosome-related ...
Salivary monoacetylated polyamines as noninvasive biomarkers for early detection and stratification of oral squamous cell carcinoma: A targeted metabolomics study [0.03%]
唾液单乙酰多胺作为口腔鳞状细胞癌早期检测和分层的非侵入性生物标志物：靶向代谢组学研究
Karthika Panneerselvam,Rajkumar Krishnan,Sathishkumar Mahadevan et al.
Karthika Panneerselvam et al.
Objectives: This study aimed to evaluate salivary monoacetylated polyamines as noninvasive biomarkers for the detection and staging of oral squamous cell carcinoma (OSCC). ...
Smoking and systemic Th17/Treg immune alterations in periodontitis: A cross-sectional study [0.03%]
吸烟与牙周病系统性Th17/Treg免疫改变的相关性：横断面研究
Sangamithra Sidharthan,Dharmarajan Gopalakrishnan,Supriya Kheur et al.
Sangamithra Sidharthan et al.
Objective: To investigate the impact of smoking on systemic and local immune responses in periodontitis, focusing on Th17 and regulatory T (Treg) cell frequencies and their associated cytokine expression. ...
Upregulated expressions of caspase-4 and -5 upon challenging with periodontal microorganisms in human gingival epithelial cells [0.03%]
人龈上皮细胞中牙周病原微生物刺激上调胱冬酶-4和-5的表达
Anupong Makeudom,Ekapong Dechtham,Nutthapong Kantrong et al.
Anupong Makeudom et al.
Objectives: Gram-negative periodontal microorganisms may be recognized by caspase-4/-5, lipopolysaccharide sensors, in human gingival epithelial cells (HGECs). This study aimed to determine expressions of inflammasomal bi...
Genetic polymorphisms in headache attributed to temporomandibular disorder: A case-control study [0.03%]
颞下颌紊乱归因头痛的遗传多态性：一项病例对照研究
Camilla Porto Campello,Cleidiel Aparecido Araujo Lemos,Elker Lene Santos de Lima et al.
Camilla Porto Campello et al.
Objective: The aim of this study was to examine the relationship between three single nucleotide polymorphisms (SNPs): -308 G/A TNF-α, -174 G/C IL-6, and C677T MTHFR and the presence of headache attributed to temporomand...
Mouthrinses differentially rewire salivary virus-microbiome interaction dynamics in COVID-19 patients: A randomized controlled trial [0.03%]
漱口水可调节新冠病毒患者唾液病毒与微生物的动态相互作用：一项随机对照试验
Armelia Sari Widyarman,Rika Bur,Nadeeka S Udawatte et al.
Armelia Sari Widyarman et al.
Objective: In this randomized clinical trial (RCT) we evaluated the efficacy of mouthrinses containing sodium chlorite (NaClO2), povidone iodine (PVP-I), cetylpyridinium chloride (CPC) compared to sterile water control in...
Is salivary melatonin an indicator of periodontal disease severity? A systematic review and meta-analysis [0.03%]
唾液褪黑素能作为牙周病严重程度的指标吗？系统评价和Meta分析
Rodrigo Martins Dos Santos,Franciane Duarte Gonçalves,Liliane Moretti Carneiro et al.
Rodrigo Martins Dos Santos et al.
Objectives: To evaluate, through a systematic review and meta-analysis, the differences in salivary melatonin (S-MEL) levels between individuals with periodontal disease and healthy individuals. ...
Cellular passages modulate pre-osteoblast responses to bisphosphonate in high-passage cell models [0.03%]
细胞通道调节高代次细胞模型中前成骨细胞对双磷酸盐的反应
Charukrit Lilakhunakon,Somying Patntirapong
Charukrit Lilakhunakon
Objective: This study examined the effects of cell passages, drug treatment, or interaction between cell passage and drug treatment on pre-osteoblast growth and activities. ...
Liraglutide enhances bone regeneration in a critical-size calvarial defect model in male rats: A comparative study with autogenous grafts, allografts, and xenografts [0.03%]
利拉鲁肽通过与自体移植、同种异体移植和异种移植比较研究促进雄性大鼠颅骨临界尺寸缺损模型中的骨再生
Necati Zavrak,Aysan Lektemur Alpan,Özlem Özmen
Necati Zavrak
Objective: Bone grafting materials are widely used in the treatment of critical-sized bone defects, and pharmacological agents with the potential to enhance their regenerative potential have been of great interest. The pu...
Experts' narrative review "Mastication, Hippocampal Structure Changes and Cognition" [0.03%]
专家述评《咀嚼、海马结构变化与认知》
Maria Grazia Piancino
Maria Grazia Piancino
Objective: Recent evidence highlights a fundamental link between masticatory function and brain health. Once regarded solely as a peripheral motor activity for food processing and occlusal balance, mastication is now reco...