Decitabine inhibits the malignant transformation of oral potentially malignant disorders by upregulating SOX1 expression via demethylation to modulate the wnt pathway in a male rat model [0.03%]
地西他滨通过去甲基化上调SOX1表达来抑制潜在恶性口腔病变的恶性转化：大鼠模型中的Wnt途径调节作用
Tianlu Wang,Peiyan Wang,Xiaohong Zhan et al.
Tianlu Wang et al.
Objective: To explore the treatment effects of Decitabine (DAC) on Oral potentially malignant disorders (OPMDs) and understand the mechanism involved. Des...
Long non-coding RNA TMPO-AS1 promotes chronic periodontitis progression by negatively regulating miR-383-5p expression in human periodontal stromal cells [0.03%]
长非编码RNA TMPO-AS1通过抑制miR-383-5p在人牙周膜成纤维细胞中促进慢性牙周炎进展
Jingyang Sun,Juxiang Shen
Jingyang Sun
Objectives: This study aimed to investigate the molecular mechanisms by which TMPO-AS1 regulates inflammation and osteogenic differentiation in chronic periodontitis (CP). ...
The role of FAT family cadherins in craniofacial development: A scoping review [0.03%]
脂肪家族钙黏蛋白在颅面发育中的作用：综述性研究
Qing Yuan,Yuchen Liu,Martin Degen et al.
Qing Yuan et al.
Objectives: To map the existing evidence on the role of FAT family cadherins in craniofacial development, identify knowledge gaps, and inform future research directions in this field. ...
Silver diamine fluoride for dental caries: the good, the bad, and the ugly - insights from preclinical evidence [0.03%]
银氟化氨治疗龋齿：来自动物实验的见解
Devaraj Ezhilarasan
Devaraj Ezhilarasan
Objective: Dental caries remains a major global public health problem, particularly in early childhood. Silver diamine fluoride (SDF) has gained attention as a cost-effective agent for arresting caries and enhancing remin...
Salivary protein profile of PLHIV on long-term antiretroviral therapy suggests latent reservoir and immune exhaustion [0.03%]
长期接受抗逆转录病毒治疗的PLHIV的唾液蛋白谱提示潜伏库和免疫衰竭
Nayara Flores Macedo,Gabriela Leite Baggio,Jair Caetano de Oliveira et al.
Nayara Flores Macedo et al.
Objective: To compare salivary protein profiles in people living with HIV (PLHIV) undergoing antiretroviral therapy (ART) for different durations. This cross-sectional study examined how long-term ART affects the salivary...
Assessing convolutional neural networks architectures for orthopantomography image analysis: Judicial dental age threshold classification [0.03%]
评估卷积神经网络架构以进行正 panoramics 放射图像分析：牙科年龄阈司法分类
Cristiana Palmela Pereira,António Figueiras,Valon Nushi et al.
Cristiana Palmela Pereira et al.
Objective: Forensic dental age assessment is required when documentary evidence is absent or unreliable, and judicial decisions often depend on whether an individual falls below or above legally defined age thresholds. Th...
P75NTR promotes radiation-induced submandibular gland epithelial cell apoptosis via the ceramide signaling [0.03%]
P75NTR通过鞘氨醇信号促进放射诱导的下颌下腺上皮细胞凋亡
Shen-Sui Li,Xu-Dong Tian,Ju-Kun Song et al.
Shen-Sui Li et al.
Objective: Radiotherapy for head and neck cancers often damages normal tissues, including radiation-induced sialadenitis. The role of the p75 neurotrophin receptor (p75NTR) in radiation injury is dual; however, its mechan...
Evidence of a millennia-old association between a methanogenic archaeon and a bacterium in dental calculus: A re-analysis of ancient and modern metagenomic datasets [0.03%]
对古代和现代元基因组数据集的再分析表明甲烷生成古菌与细菌在牙石中的千年的关联性证据
Virginie Pilliol,Mamadou Beye,Mahmoud A Boualam et al.
Virginie Pilliol et al.
Objectives: Granehäll et al. (2021) identified TS-2 as an unknown Methanobrevibacter lineage abundant in ancient dental calculus, less prevalent in modern samples, and not linked to any cultivated representative. We aime...
Temporal histological and immunohistochemical characterization of experimental dental pulp inflammation in rats [0.03%]
大鼠实验性牙髓炎症的组织病理学和免疫组织化学特征分析
Julissa Denisse Arguello Alvarado,Rafaela Ricci,Romulo de Oliveira Sales-Junior et al.
Julissa Denisse Arguello Alvarado et al.
Objective: To establish a temporal histological and immunohistochemical profile in a rat model of pulpitis by assessing cytokine immunoreactivity at the root canal orifice over time. ...
mRNA and lncRNA expression profiles as potential targets for diagnosis and treatment of oral lichen planus [0.03%]
口腔扁平苔藓的诊断和治疗的潜在靶点的 mRNA 和 lncRNA 表达谱分析
Janghyun Kim,Jeong-Won Kim,Sook Jung Yun et al.
Janghyun Kim et al.
Objective: This study aimed to identify differentially expressed (DE) mRNAs and long noncoding RNAs (lncRNAs) between oral lichen planus (OLP) and skin lichen planus (SLP) to elucidate the molecular mechanisms driving the...