Long-term prognostic value of residual lipid burden in acute myocardial infarction [0.03%]
急性心肌梗死后残余脂质负担的长期预后价值
Chao Fang,Lina Cui,Jiawei Zhao et al.
Chao Fang et al.
Background and aims: To examine the clinical significance and prognostic value of total coronary artery non-culprit residual lipid burden (RLB) after percutaneous coronary intervention in acute myocardial infarction (AMI)...
Concordance of Lipoprotein(a) measurements in mg/dL and nmol/L: Insights from the Lp(a)HORIZON trial [0.03%]
Lp（a）HORIZON研究试验中的Lp（a）检测值在mg/dL和nmol/L单位的一致性分析
Leslie Cho,Børge G Nordestgaard,Bliss Chang et al.
Leslie Cho et al.
Background and aim: Challenges in measurement standardization have complicated both research and clinical care. We assessed the concordance of Lp(a) concentration measured in mg/dL and nmol/L using the Roche Tina-quant Li...
Safety of very low LDL-cholesterol: Ten common concerns, misconceptions, and evidence-based clarifications [0.03%]
极低LDL胆固醇水平的安全性：十大常见问题、误解及基于证据的解释
Luz Clemencia Zárate-Correa,Ángel García-Peña,Sergio Emanuel Kaiser et al.
Luz Clemencia Zárate-Correa et al.
Background and aims: Contemporary guidelines, including 2025 ESC/EAS focused update, recommend lower LDL-cholesterol (LDL-C) goals for selected high-risk patients, renewing safety concerns about achieving very low LDL-C, ...
Zobaida Al-Baldawi,Armen Erzingatzian,Isabelle Ruel et al.
Zobaida Al-Baldawi et al.
Background and aims: Homozygous familial hypercholesterolemia (HoFH) is a rare disorder of lipid metabolism, characterized by extremely elevated low-density lipoprotein cholesterol (LDL-C) levels and marked premature card...
European and Canadian derived risk prediction equations for atherosclerotic cardiovascular disease are valid in Australian patients with genetically confirmed familial hypercholesterolaemia [0.03%]
欧洲和加拿大动脉粥样硬化心血管疾病的衍生风险预测量表可用于遗传证实的家族性高胆固醇血症澳大利亚患者人群中
Seyed Saeed Tamehri Zadeh,Dick C Chan,Jing Pang et al.
Seyed Saeed Tamehri Zadeh et al.
Background and aims: Familial hypercholesterolaemia (FH) is a co-dominantly inherited condition that leads to enhanced risk of atherosclerotic cardiovascular disease (ASCVD). We evaluated and compared the discriminatory a...
Elevated remnant cholesterol, but not LDL cholesterol, explains part of recurrent ASCVD events in individuals with and without impaired renal function: the Copenhagen General Population Study and the UK Biobank [0.03%]
余胆固醇升高而不是LDL胆固醇可解释肾功能受损个体中重复发生的动脉粥样硬化性心血管疾病事件：哥本哈根一般人群研究和英国生物样本库中的相关证据
Fie Pilsgaard,Frida Emanuelsson,Signe Vedel-Krogh et al.
Fie Pilsgaard et al.
Background and aims: Individuals with impaired renal function are at high risk of atherosclerotic cardiovascular disease (ASCVD). We hypothesized that elevated remnant cholesterol explains part of recurrent ASCVD event ri...
Coronary macrovascular and microvascular involvement and their association with distinct circulating microRNA patterns: The ANFIBIO Study [0.03%]
冠状动脉大血管和微血管损伤及其与不同循环微小RNA模式的关系：ANFIBIO研究
Lucía Matute-Blanco,Iván D Benítez,Thalía Belmonte et al.
Lucía Matute-Blanco et al.
Background and aims: Circulating microRNAs (miRNAs) may represent promising candidate biomarkers of chronic coronary syndrome (CCS). Nevertheless, their relationship with patterns of coronary dysfunction remains underexpl...
Sex-specific gene expression signatures of calcific aortic valve stenosis in a large collection of human tissues [0.03%]
基于大量人类组织的主动脉瓣狭窄性别特异性基因表达标志物分析
Ursula Houessou,Pardis Zamani,Hasanga D Manikpurage et al.
Ursula Houessou et al.
Background and aims: The mechanisms underlying sex differences in calcific aortic valve stenosis (CAVS) are poorly understood. We aimed to uncover sex-specific gene expression signatures of CAVS, including genes located o...
Voices of those recruiting: A qualitative study on barriers and enablers to women's participation in cardiovascular trials [0.03%]
招募者的声音：一项关于阻碍和促进女性参与心血管试验因素的定性研究
Marte F van der Bijl,Linda M Beens,Yolande Appelman et al.
Marte F van der Bijl et al.
Background and aims: Cardiovascular disease is the leading cause of death among women, yet women remain underrepresented in cardiovascular clinical trials. This qualitative study explored perspectives of research personne...
LDL and non-HDL cholesterol with the lowest mortality in the general population in 1991-2018 [0.03%]
1991-2018年一般人群中LDL和非HDL胆固醇的最低死亡率水平
Takahito Doi,Anne Langsted,Børge G Nordestgaard et al.
Takahito Doi et al.
Background and aims: Over the past few decades, low-density lipoprotein (LDL) and non-high-density lipoprotein (non-HDL) cholesterol levels in the general population have lowered. However, it is unclear whether these tren...