Long-term average atherogenic index of plasma and cardiovascular mortality in 8.9 million Korean adults: A nationwide cohort study [0.03%]
基于韩国890万成年人的全国队列研究：长期平均血浆致动脉粥样硬化指数与心血管病死亡率的关系
Hyeon Hui Kang,Yoonjong Bae,Hoseob Kim et al.
Hyeon Hui Kang et al.
Background and aims: To evaluate the association between the atherogenic index of plasma (AIP) and cardiovascular disease (CVD) mortality, with a particular focus on young adults, individuals with low-density lipoprotein ...
Lipid profile in pediatric and adult patients with lysosomal acid lipase deficiency treated with sebelipase alfa: longitudinal evidence from the International LAL-D Registry [0.03%]
α-糖苷酶治疗的儿科和成人溶酶体酸性脂酶缺乏患者的血脂谱：国际LAL-D登记处的纵向证据
Don P Wilson,Lorenzo D&#x;Antiga,Manisha Balwani et al.
Don P Wilson et al.
Background and aims: Dyslipidemia, including elevated low-density lipoprotein cholesterol (LDL-C) and decreased high-density lipoprotein cholesterol (HDL-C), is common among patients with lysosomal acid lipase deficiency ...
Multicenter Study
Atherosclerosis. 2026 Oct:421:121867. DOI:10.1016/j.atherosclerosis.2026.121867 2026
Lipoprotein(a) carries triglyceride species associated with incident cardiovascular disease [0.03%]
载脂蛋白(a)携带与动脉粥样硬化性心血管病事件相关的三酰甘油类物质
Kaloyan Takov,Sider Penkov,Raimund Pechlaner et al.
Kaloyan Takov et al.
Background and aims: Lipoprotein(a) [Lp(a)] is described as a low-density lipoprotein-like particle, but recent work suggests heterogeneity, including triglyceride (TG)-rich features. We investigated whether native Lp(a) ...
The adventitia, vascular inflammation, and the intersection of hypertension and vascular disease [0.03%]
外膜、血管炎症以及高血压与血管疾病的关系
David G Harrison
David G Harrison
Hypertension is a leading risk factor for cardiovascular disease, promoting atherosclerosis through interrelated mechanisms of mechanical stress and vascular inflammation. The adventitia and perivascular adipose tissue have emerged as criti...
Lactate promotes macrophage-derived foam cell formation and atherosclerosis [0.03%]
乳酸促进巨噬细胞源性泡沫细胞形成并促动脉粥样硬化形成
Zhenzhen Jia,Shuaiyin Liu,Zhifeng Yang et al.
Zhenzhen Jia et al.
Background and aims: Diabetes accelerates atherosclerosis progression by disrupting multiple metabolic pathways. However, the role and mechanisms of lactate-a glycolytic byproduct significantly elevated in diabetic patien...
Lp(a) testing and treatment with Lp(a)-lowering therapies in the primary and secondary prevention of cardiovascular disease in high income countries: A preliminary health technology assessment [0.03%]
高收入国家中评估Lp(a)检测和使用降Lp(a)治疗在心血管疾病一级预防和二级预防中的应用：一项卫生技术评估初步报告
Jedidiah I Morton,Florian Kronenberg,Raul D Santos et al.
Jedidiah I Morton et al.
Background and aims: New therapies targeting Lipoprotein(a) (Lp(a)) are anticipated to enter clinical practice soon. We aimed to estimate the benefits of Lp(a) lowering therapy and threshold price at which treatment with ...
Deficiency of the aryl hydrocarbon receptor in intestinal epithelial cells, but not hepatocytes, ameliorates atherosclerosis development by sex-dependently targeting the lipid metabolism [0.03%]
肠道上皮细胞而非肝细胞的芳香烃受体缺乏通过性别依赖性靶向脂质代谢来改善动脉粥样硬化的发展
Rosanna Huchzermeier,Leonida Rakateli,Melissa Corcini-Berndt et al.
Rosanna Huchzermeier et al.
Background: The aryl hydrocarbon receptor (AhR) is a well-described regulator of xenobiotic stimuli, but recent studies highlight a potential bidirectional role in mediating lipid metabolism. The precise mechanisms underl...
Hematopoietic loss of Y chromosome and risk of symptomatic peripheral artery disease in men [0.03%]
男性中造血染色体丢失与症状性外周动脉疾病风险的关系
Chenshu Li,Dongdong Tang,Sultana Monira Hussain et al.
Chenshu Li et al.
Background: Mosaic loss of chromosome Y (mLOY) is the most common acquired somatic mutation in men and has been linked to multiple age-related diseases, including cardiovascular diseases. However, its association with sym...
Dietary vitamin K intakes and atherosclerotic cardiovascular disease incidence: Findings from the UK biobank [0.03%]
来自英国生物样本库队列研究的维生素K摄入与动脉粥样硬化性心血管病发病风险关系的探索性分析
Montana Dupuy,Chengfeng Li,Pratik Pokharel et al.
Montana Dupuy et al.
Background and aims: Vitamin K is essential for processes that inhibit vascular and valvular calcification, attributes of atherosclerotic cardiovascular diseases (ASCVDs) and aortic stenosis (AS). Relationships between di...
Universal paediatric screening for familial hypercholesterolaemia: Lessons learnt from our pilot study EARLIE [0.03%]
耳 Lipid 序列研究中对家族性高胆固醇血症进行儿科普查的经验教训
Marianne Becker,Valéry Bocquet,Françoise Fandel et al.
Marianne Becker et al.
Background and aims: Universal screening for familial hypercholesterolaemia (FH) has been proposed; but implementation remains limited. This pilot study assesses the feasibility and efficacy of a screening based on a capi...