Relationship of low-density lipoprotein-cholesterol and lipoprotein(a) to cardiovascular risk: The Multi-Ethnic Study of Atherosclerosis (MESA) [0.03%]
低密度脂蛋白胆固醇和脂蛋白(a)与心血管风险的关系：动脉粥样硬化多元民族研究（MESA）
Rishi Rikhi,Aziz Hammoud,Nicklaus Ashburn et al.
Rishi Rikhi et al.
Background and aims: Plasma low-density lipoprotein cholesterol (LDL-C) and lipoprotein(a) (Lp(a)) are both associated with coronary heart disease (CHD). This study investigated whether elevated plasma Lp(a) concentration...
The individual and joint associations of depression and sleep duration with cardiometabolic diseases and mortality: A prospective cohort study [0.03%]
抑郁症和睡眠时长与心血管代谢性疾病及死亡率的单一及联合相关性：一项前瞻性队列研究
Xunjie Cheng,Feiyun Ouyang,Tianqi Ma et al.
Xunjie Cheng et al.
Background and aims: Depression and sleep duration were only mutually adjusted in a few studies, and it is unknown whether these two factors are independent or overlapping risk factors for cardiometabolic diseases (CMDs) ...
Gene set analysis of transcriptomics data identifies new biological processes associated with early markers of atherosclerosis but not with those of osteoporosis: Atherosclerosis-osteoporosis co/multimorbidity study in the Young Finns Study [0.03%]
基因集分析鉴定出与动脉粥样硬化早期分子标志物而非骨质疏松分子标志物相关的新生物过程：青年芬兰人研究中的动脉粥样硬化/骨质疏松共/多病状况研究
Binisha H Mishra,Harri Sievänen,Emma Raitoharju et al.
Binisha H Mishra et al.
Aim: We aimed at identifying the shared biological processes underlying atherosclerosis-osteoporosis co/multimorbidity. Methods: We per...
Seth Klusewitz,Edward A Hulten
Seth Klusewitz
Genetic proxies for PCSK9 inhibition associate with lipoprotein(a): Effects on coronary artery disease and ischemic stroke [0.03%]
PCSK9遗传替代与Lp(a)关联：对冠状动脉疾病和缺血性卒中的影响
Gian Marco De Marchis,Tolga D Dittrich,Rainer Malik et al.
Gian Marco De Marchis et al.
Background and aims: Post hoc analyses of clinical trials show that PCSK9 inhibitors might lower lipoprotein(a), but whether this effect contributes to reductions in cardiovascular risk remains unknown. We aimed to assess...
Adherence to Life's simple 7 is associated with better carotid properties [0.03%]
坚持健康生活七要素与更好的颈动脉性质有关
Gilles Nève,Pirjo Komulainen,Kai Savonen et al.
Gilles Nève et al.
Background and aims: Cardiovascular health scores have emerged as a simple way to assess the risk to suffer from a cardiovascular disease. The American Heart Association's Life's Simple 7 constitutes of modifiable lifesty...
The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index [0.03%]
双侧踝臂指数降低患者的心血管疾病患病率高于单侧踝臂指数降低患者
Tatsuya Maruhashi,Masato Kajikawa,Shinji Kishimoto et al.
Tatsuya Maruhashi et al.
Background and aims: Ankle-brachial index (ABI) has been used as a vascular marker of atherosclerosis for cardiovascular risk assessment. However, it is unclear whether there is a difference in cardiovascular risk between...
Vascular smooth muscle- and myeloid cell-derived integrin α9β1 does not directly mediate the development of atherosclerosis in mice [0.03%]
小鼠血管平滑肌细胞和髓系细胞源性整合素α9β1不直接介导动脉粥样硬化的发展
In-Hyuk Jung,Jared S Elenbaas,Kendall H Burks et al.
In-Hyuk Jung et al.
Background and aims: Sushi, von Willebrand factor type A, EGF pentraxin domain-containing 1 (SVEP1), an extracellular matrix protein, is a human coronary artery disease locus that promotes atherosclerosis. We previously d...
Low endogenous estradiol levels are associated with elevated risk of cardiovascular disease mortality in young and middle-aged men in the United States [0.03%]
美国年轻及中年男性内源性雌二醇水平低与心血管疾病死亡率升高有关
Duke Appiah,Sujata Luitel,Chike C Nwabuo et al.
Duke Appiah et al.
Background and aims: Evidence for the association of total estradiol (E2) with cardiovascular disease (CVD) in young men is limited. We investigated the association of total E2 or free estradiol (FE2) and CVD mortality in...
Neck-brain integrated ultrasound as a noninvasive screening tool to identify morphological features of middle cerebral artery disease [0.03%]
颈脑一体化超声作为非侵入性筛查工具识别大脑中动脉疾病的形态特征
Jie Zhang,Shouchun Wang,Ying Chen et al.
Jie Zhang et al.
Background and aims: Endovascular treatment is suitable for middle cerebral artery (MCA) with focal lesion. Therefore, accurate evaluation of the morphological features of MCA disease is critical. Ultrasonography is commo...