Katharina Lechner,Benjamin Lechner,Oliver Weingärtner
Katharina Lechner
Hypertension, smoking and adiposity: old enemies, new priorities in FH [0.03%]
高血压、吸烟和肥胖：FH中的老对手，新重点
Arturo Cesaro,Paolo Calabrò,Stefano Romeo
Arturo Cesaro
The persistent challenge of medication adherence after myocardial infarction in the real-world: Why compliance keeps taking the hit [0.03%]
现实世界中急性心肌梗死后持续存在的用药依从性挑战：为何遵医嘱服药如此困难
Enzo Emanuele,Jacques D Barth
Enzo Emanuele
Risk factors for atherosclerotic cardiovascular disease in individuals with heterozygous familial hypercholesterolemia: a systematic review and meta-analysis [0.03%]
杂合子家族性高胆固醇血症患者动脉粥样硬化性心血管疾病的风险因素：系统评价和meta分析
María Elena Mansilla-Rodríguez,José Luis Sánchez-Ramos,Alina Rigabert Sánchez-Junco et al.
María Elena Mansilla-Rodríguez et al.
Background and aims: Familial hypercholesterolemia (FH) is a highly prevalent monogenic disorder characterized by elevated low-density lipoprotein-cholesterol (LDL-C) levels and premature atherosclerotic cardiovascular di...
Cost-effectiveness of alternative cascade screening strategies for familial hypercholesterolemia with realistic cascade screening acceptance rates and use of novel treatment [0.03%]
基于现实接受率和新型治疗方法的载脂蛋白B检测策略的成本效益分析
Jing Lou,Kok Joon Chong,Sharon Li Ting Pek et al.
Jing Lou et al.
Background and aims: Cascade screening (CS) for familial hypercholesterolemia (FH) has been found to be cost-effective in many published studies. However, most existing studies (i) ignored or overstated first-degree relat...
Xanthelasma and its association with developing major cardio-cerebrovascular events [0.03%]
眼睑黄斑瘤与重大心脑血管事件的关系研究
Negin Yavari,Karen M Wai,Amer F Alsoudi et al.
Negin Yavari et al.
Background and aim: To evaluate short- and long-term incidence of major adverse cardio-cerebrovascular events (MACCEs) in patients with xanthelasma. Metho...
Inhibiting AIDA suppresses VSMC-derived foam cell formation and atherosclerosis by hindering CD36 membrane translocation [0.03%]
抑制AIDA可阻碍CD36膜转移从而抑制血管平滑肌细胞衍生泡沫细胞的形成及动脉粥样硬化的发展
Ruolin Lyu,Ziyi He,Na Li et al.
Ruolin Lyu et al.
Vascular smooth muscle cell (VSMC)-derived foam cells critically drive atherosclerotic plaque progression, yet their regulatory mechanisms remain incompletely understood. This study aimed to elucidate the pathophysiological role of the VSMC...
AI prediction models with omics data utilization for atherosclerosis: A systematic scoping review and meta-analysis [0.03%]
整合组学数据的动脉粥样硬化人工智能预测模型系统综述和元分析研究
Yunbeom Lee,Kwanwoo Park,Ji Hyun Lee et al.
Yunbeom Lee et al.
Background and aims: Cardiovascular disease (CVD) remains a leading cause of global mortality, necessitating advanced methodologies to elucidate its complex pathophysiology. The application of artificial intelligence (AI)...
Proteomics and ex vivo plaque culture identify the insulin-like growth factor axis as a potential regulator of matrix remodelling in carotid plaques [0.03%]
蛋白组学和颈动脉斑块的体外培养鉴定出胰岛素样生长因子轴可能为颈动脉斑块基质重塑的调节因子
Sara M Jørgensen,Karen C Yang-Jensen,Karin Yeung et al.
Sara M Jørgensen et al.
Background and aims: Rupture of carotid atherosclerotic plaques is a significant cause of stroke. We have previously analyzed 21 plaques by mass spectrometry and reported differing proteomic profiles between morphological...
Evolocumab in patients with multivessel coronary disease after acute myocardial infarction: A target trial emulation [0.03%]
在接受急性心肌梗死后多血管冠状动脉疾病的患者中使用Evolocumab的疗效：靶标试验模拟研究
Jinying Zhou,Xiaoning Guo,Wei Gao et al.
Jinying Zhou et al.
Background and aims: The proprotein convertase subtilisin/kexin type 9 inhibitors, i.e. evolocumab, promote coronary plaque regression in patients with acute myocardial infarction (AMI). However, its clinical benefit for ...