The therapeutic potential of Dihydroartemisinin for autoimmune disease: Effects on the Th17/Treg balance [0.03%]
双氢青蒿素治疗自身免疫病的潜力：对Th17/Treg平衡的影响
Yuwen Mao,Yudong Gao,Juncheng Zhou et al.
Yuwen Mao et al.
Autoimmune diseases (AID) are chronic inflammatory conditions resulting from aberrant recognition of self-antigens by the immune system. Appropriate ratios of the subsets of CD4+ T cells, T helper cells 17 (Th17) and regulatory T cells (Tre...
Identification of a novel multi epitope vaccine against human herpes virus 7 (HHV-7) to Combat CNS disorders in children and adolescents using Subtractive Proteomics and immunoinformatic approaches [0.03%]
利用免疫信息学和减法蛋白质组学方法鉴定新型多表位疫苗以对抗人疱疹病毒7(HHV-7)引起的儿童和青少年CNS疾病
Muhammad Naveed,Adeeba Ali,Tariq Aziz et al.
Muhammad Naveed et al.
Human herpesvirus 7 (HHV-7) is a very common pathogen associated with neurological and systemic disorders, particularly in children and adolescents. Although it has a wide range and a heavy disease burden across the globe, there has been no...
Characterization of an inherited HLA-B gene deletion in a candidate for hematopoietic cell transplantation [0.03%]
造血干细胞移植候选者HLA-B基因遗传缺失的特征分析
Liying Chi,Patrick R Blackburn,Alexa N Siskar et al.
Liying Chi et al.
Accurate high-resolution genotyping of HLA genes for hematopoietic cell transplant (HCT) recipients provides critical information for matching and donor selection. We describe unusual family typing for a pediatric transplant candidate which...
Next-Generation regulatory T cell therapies: translational considerations for inflammatory bowel disease [0.03%]
下一代调节性T细胞疗法：炎症性肠病的转化考虑因素
Michelle M Gonzalez,Gloria B Kim,Mohsen Khosravi Maharlooei et al.
Michelle M Gonzalez et al.
Association between ADAM33 gene polymorphisms and asthma in the Zhuang population of China [0.03%]
ADAM33基因多态性与中国壮族人群哮喘的相关分析
Zan-Mei Qin,Xue-Mei Huang,Xuan Wei et al.
Zan-Mei Qin et al.
Objective: To explore the potential association between five single nucleotide polymorphisms (SNPs) (rs44707, rs612709, rs598418, rs2280089, and rs574174) in the ADAM33 gene and asthma susceptibility in the Zhuang populat...
Beyond HLA: An adaptive nanopore sequencing assay for simultaneous HLA and blood group profiling in transplantation [0.03%]
超越HLA：移植中同时进行HLA和血型谱分析的纳米孔测序测定法
S Grasedieck,L MacIntyre,E Roulis et al.
S Grasedieck et al.
Aim: Transplantation is a life-saving therapy but carries significant risks, including rejection, graft-versus-host disease, infection, and malignancy, which can lead to graft failure and death. These complications arise ...
Assessing the reliability of the PAK-LX HLA Class I bead in platelet transfusion compatibility testing [0.03%]
评估PLT-LX HLAⅠ类微球在血小板交叉配型中的可靠性
Haley Enten,Abdelhamid Liacini,Deanna Janes et al.
Haley Enten et al.
Purpose: PAK-LX, a Luminex-based assay for detecting platelet-specific glycoproteins and HLA class I antibodies, has shown limited reliability for HLA immunization. A prior study reported a 37% discrepancy compared to the...
Association between IL and 17A (rs2275913), IL-4 (rs2070874), NLRP3 (rs10754558) polymorphisms and COVID-19 in a cohort of professionals who worked in the first pandemic wave [0.03%]
IL-17A（rs2275913）、IL-4（rs2070874）、NLRP3（rs10754558）多态性与新冠疫情中一线工作人员的相关性研究
Marcelo Cleyton da Silva Vieira,Beatriz Dos Reis Marcelino,Marcos Jessé Abrahão Silva et al.
Marcelo Cleyton da Silva Vieira et al.
Introduction: Host genetic polymorphisms in inflammatory mediators may influence COVID-19 clinical outcomes. This study investigated associations between IL and 17A (rs2275913), IL-4 (rs2070874), and NLRP3 (rs10754558) po...
Pre-existing influenza antibodies, younger age, and increased CD4 TE+EM predict influenza vaccination responses in transplant recipients [0.03%]
移植受者中预存的流感抗体、较年轻的年龄和增加的CD4 TE+EM预测流感疫苗接种的反应
Christiane Rollenhagen,Gomathy Parvathinathan,Margaret R Stedman et al.
Christiane Rollenhagen et al.
Recipients of kidney transplants require lifelong immunosuppression therapy which is associated with a reduced response to vaccinations. We conducted a longitudinal study of influenza vaccination in US Veteran kidney transplant recipients a...
FALSE POSITIVE REACTION AGAINST 73ID EPLET IN SINGLE ANTIGEN BEAD ASSAY [0.03%]
单抗原微粒检测中73id eplet位点假阳性反应
Isaú Henrique Noronha,Maria Gebarse-DeLima,Luiza Zainotti Miguel Fahur Bottino et al.
Isaú Henrique Noronha et al.
The purpose of this study was to investigate possible false-positive reactions against HLA-A*31:01, -A*33:01, and -A*33:03 beads in One Lambda single antigen bead assay (OL-SAB) solely explained by the 73ID eplet (73ID profile). As this epl...