In silico Identification of novel vaccine candidates against Multidrug-Resistant Pseudomonas aeruginosa using subtractive proteomics and immunoinformatics [0.03%]
基于免疫信息学和生物信息学的减数蛋白质组学鉴定多重耐药绿脓杆菌的新疫苗靶标蛋白质候选者
Alhanouf I Al-Harbi,Fahad M Alshabrmi,Eid A Alatawi et al.
Alhanouf I Al-Harbi et al.
Pseudomonas aeruginosa, a notorious pathogen, frequently presents in hospitals and poses numerous health issues due to its drug resistance, making treatment challenging. The rise of multidrug-resistant microorganisms emphasizes the crucial ...
Exploring eNOS-Caveolin-1 interaction in placentas of SARS-Cov-2 positive pregnancies [0.03%]
探讨SARS-CoV-2阳性妊娠胎盘中eNOS-Caveolin-1相互作用
Canan Hurdag,T Önel,K Sandal et al.
Canan Hurdag et al.
Background: The placenta serves as a vital interface between mother and fetus, facilitating nutrient exchange and immune regulation. Although generally effective in preventing pathogen transmission, some viruses such as C...
A Comprehensive comparative assessment of mean Fluorescence Intensity of Luminex single Antigen bead tests between laboratories and commercial platforms: A report from the Italian Histocompatibility Network [0.03%]
意大利组织相容性网络Luminex单抗原微球检测均荧光强度的全面比较评估：实验室与商业平台之间的对比研究报告
Antonina Piazza,Giovanni Rombolà,Umberto Maggiore et al.
Antonina Piazza et al.
Reliable and reproducible testing of Donor Specific HLA-Antibodies (DSA) is essential for clinical decisions in organ transplantation. In this prospective multicentre study from the Italian Transplant Network, we assessed reproducibility an...
A single-center, randomized, double-blind, positive-controlled, phase IV clinical trial to assess the immunogenicity and safety of adsorbed tetanus toxoid vaccine in individuals aged ≥16 years [0.03%]
tetanus toxoid吸附百白破儿童疫苗免疫原性和安全性的单中心随机双盲阳性平行对照Ⅳ期临床试验
Qinghu Guan,Jun Liu,Miaomiao Tang et al.
Qinghu Guan et al.
Background: Tetanus prevention is effectively managed in infants and young children, yet there remains a need for enhanced measures to improve tetanus prevention among adults. ...
Bruce Young
Bruce Young
Exploring the role of genetic variants in susceptibility to autoimmune Diseases: A molecular genetics approach [0.03%]
自身免疫病遗传易感基因研究的分子遗传学策略
Fatemah S Basingab
Fatemah S Basingab
Autoimmune diseases occur when the immune system mistakenly attacks healthy tissues, leading to chronic inflammation and progressive organ damage. These conditions affect millions worldwide and often result in long-term disability. The unde...
NLRP3 genetic variants and their impact on psoriasis susceptibility, severity, and risk of psoriatic arthritis [0.03%]
NLRP3基因变异及其对银屑病易感性、严重性和银屑病关节炎风险的影响
Cássio Rafael Moreira,Camila Cataldi de Alcântara,Ligia Marcia Mario Martin et al.
Cássio Rafael Moreira et al.
Psoriasis (PsO) is a chronic, immune-mediated inflammatory disease with systemic manifestations. Its etiology involves an interaction between genetic, immunologic, and environmental factors. The NLRP3 inflammasome plays a key role in innate...
Immunological risk assessment for safety net kidney transplant Candidates: A case series [0.03%]
安全网肾移植受者的免疫风险评估：一系列案例研究
Nicole Hayde,Dagny Von Ahrens,Enver Akalin et al.
Nicole Hayde et al.
Reduction in pre-transplant HLA donor specific antibodies (DSA) is a known phenomenon after liver or simultaneous liver kidney (SLK) transplants. However, kidney after liver transplant may be associated with increased immunologic risk, in h...
A Quintiliano,C H Cramer,A J Bentall et al.
A Quintiliano et al.
Eplet mismatch (MM) quantification is a valuable tool for refining histocompatibility in kidney transplantation, especially at HLA-DR/DQ loci. However, zero MM at these loci does not ensure complete immunological safety. We report a 17-year...
Genotyping BK virus in kidney transplant recipients using novel algorithm [0.03%]
利用新型算法对肾移植受者进行BK病毒基因分型
Deema Ibrahim Fallatah,Hafeez Aderinsayo Adekola,Steve Christmas
Deema Ibrahim Fallatah
This study investigated the prevalence of BKV subtypes in kidney transplant recipients and evaluates their association with viral load and BKVAN risk. A total of 32 kidney transplant recipients with confirmed BKV infection were included in ...