Predictive Value of End-tidal Carbon Dioxide for Return of Spontaneous Circulation, Survival, and Neurological Outcomes in Adult Cardiac Arrest Patients: A Prospective Study [0.03%]
成人心脏病患者的自主循环恢复、存活率及神经系统预后与呼气末二氧化碳预测价值：一项前瞻性研究
Xian-Juan Gou,Wei-Yan Tian,Xiao-Li He et al.
Xian-Juan Gou et al.
Purpose: To analyze the factors influencing the return of spontaneous circulation (ROSC) in adult patients with cardiac arrest (CA) in the emergency department and to explore the value of end-tidal carbon dioxide (PETCO₂...
Assessing The Current Regulatory Landscape of Representation Within Clinical Trials for The Major Regulatory Regions: A Narrative Review [0.03%]
主要监管区域临床试验代表性当前监管格局的评估：叙述性综述
Kasey Boynton,Lina Aljuburi,Rebecca Lumsden et al.
Kasey Boynton et al.
Purpose: Health inequity persists globally, highlighting the ethical need for organizations that manage clinical trials to ensure the representation of the target population is reached. There is increasing recognition by ...
Evidence-Based Exploration of Exposure-Matched Candidate Pirfenidone Dose for East Asian Populations based on Population Pharmacokinetic Modeling and Simulation Approach [0.03%]
基于人群药代动力学模型与模拟的东方人低暴露等量吡非尼酮剂量探索性研究
Seongwon Park,Woojin Jung,Jihyun Jeon et al.
Seongwon Park et al.
Purpose: The approved maximum daily dose of pirfenidone for idiopathic pulmonary fibrosis (IPF) differs between East Asian (1,800 mg) and non-East Asian (2,400 mg) populations. This study aimed to explore exposure-matched...
Advancing Cystic Fibrosis-Related Diabetes Care With Automated Insulin Delivery Systems [0.03%]
利用自动化胰岛素输送系统推进囊性纤维化相关糖尿病的治疗
Valeria Grancini,Gianfranco Alicandro,Irene Cogliati et al.
Valeria Grancini et al.
Background: Cystic fibrosis-related diabetes (CFRD) is the most common comorbidity in cystic fibrosis (CF), associated with faster lung decline and higher mortality. Insulin is the recommended therapy, but its management ...
Benefits of Medical Cannabis in Patients With Pain Registered in the Minnesota Medical Cannabis Program [0.03%]
明尼苏达州医用大麻项目中疼痛患者的医疗大麻益处分析
Grace M Christensen,Susan J Park,David Rak
Grace M Christensen
Purpose: Medical cannabis is commonly used to treat chronic pain. Clinical trials typically use only one type and dosage of medical cannabis product, which is not reflective of real-world use. The use of a state-run medic...
Effect of Hemodialysis Time and Frequency on Cost-Effectiveness of Maintenance Hemodialysis in Chongqing, China: A Retrospective Study [0.03%]
重庆维持性血液透析治疗时间及频次对成本效益影响的回顾性研究
Jia Yang,Jing Mei,Ling Luo et al.
Jia Yang et al.
Purpose: From a health system perspective with a 1-year time horizon, this study investigated the cost-effectiveness of maintenance hemodialysis (MHD) in Chongqing, China, identified influencing factors, and provided evid...
Barriers and Facilitators for Psychedelic Research and Regulation in Brazil: Insights From Diverse Stakeholders [0.03%]
巴西迷幻剂研究与监管的障碍与促进因素：来自不同利益相关者的见解
Anna Luiza Guimarães,Fernando R Beserra,Lucas Cruz et al.
Anna Luiza Guimarães et al.
Purpose: The interest in psychedelics for health-related purposes has grown significantly over the past decade. However, there is an insufficient representation of stakeholders (eg, Indigenous groups, activists, policymak...
Comment on "Effect of Remimazolam or Propofol Combined With Esketamine on Anesthesia and Early Perioperative Neurocognitive Disorders in Patients Undergoing Thoracoscopic Partial Lung Resection: A Randomized Clinical Trial" [0.03%]
关于“瑞米唑胺或丙泊酚联合艾司氯胺酮对胸腔镜肺部分切除患者麻醉及围术期神经认知障碍的影响的随机临床试验”的讨论
Shobana Chandrasekar,Rohith Krishnan M K,Umesh Kumar
Shobana Chandrasekar
Development and Validation of a Risk Stratification Model Incorporating Serum Lactate and Albumin for Predicting Enteral Nutrition Feeding Intolerance in Patients With Sepsis [0.03%]
联合血清乳酸和白蛋白预测脓毒症患者肠内营养喂养不耐受的风险分层模型的建立及验证
YueYue Ge,Dan Ye,TianTian Shi et al.
YueYue Ge et al.
Purpose: Enteral nutrition feeding intolerance (ENFI) is a common complication in patients with sepsis and may compromise nutritional support and clinical recovery. This study aimed to develop and validate a risk stratifi...
Novel Therapeutic Treatments in Perinatal Genetics Bridging Prenatal and Postnatal Care of Genetic Conditions [0.03%]
围产期遗传学的新治疗方法：弥合遗传疾病 prenatal 和 postnatal 照顾之间的差距
Melissa L Russo,Rebecca Reimers,Asha N Talati
Melissa L Russo