Special Issue in Honor of Jack Henion, Recipient of the 2025 John B. Fenn Award for Distinguished Contribution in Mass Spectrometry [0.03%]
纪念杰克·亨尼恩教授——2025年约翰·B·芬恩质谱杰出贡献奖获得者特刊
Erin S Baker,Richard A J O&#x;Hair
Erin S Baker
T-ReXing Synthetic Cannabinoids─Unveiling Metabolite Features Suitable for Urine Screening by Trapped Ion Mobility HRMS [0.03%]
利用捕集离子淌度高分辨质谱揭示合成大麻素代谢产物的特征以进行尿液筛查(T-Rexing)
Annette Zschiesche,Ilona Nordhorn,Birgit Schneider et al.
Annette Zschiesche et al.
Targeted and untargeted mass spectrometric analyses of urine, a preferred matrix for toxicological screening, require comprehensive spectral libraries of drug metabolites. To detect new synthetic cannabinoids (SCs), biomarkers for newly eme...
Making Ozonolysis Mass Spectrometry More Accessible: A Simple LC-OzESI-MS Workflow for Carbon-Carbon Double Bond Position Elucidation in Lipids and Natural Products [0.03%]
一种简便的LC-OzESI-MS工作流程用于脂质和天然产物中碳碳双键位置阐明的臭氧化解碎片离子质谱分析法
Fayaj A Mulani,Ashraf M Omar,Qibin Zhang
Fayaj A Mulani
Elucidation of C═C unsaturation sites in biomolecules remains challenging using conventional tandem mass spectrometry techniques. Online ozonolysis inside a mass spectrometer offers a very specific C═C fragmentation strategy; however, ado...
Erin A Hirtzel,Gopal Reddy Ramidi,Xin Yan
Erin A Hirtzel
Chemical derivatization has long been employed to enhance the structural characterization of lipids by mass spectrometry (MS). In recent years, olefin aziridination has emerged as a powerful and versatile strategy in lipidomics, driven by i...
Quantifying Protein Temporal Changes with Mass Spectrometry in Plasma Samples from Breast Cancer Patients Undergoing Radiotherapy [0.03%]
乳腺癌放疗患者的血浆样本中蛋白质时间变化的质谱定量研究
Kathryn L Kapp,Catherine C Going,Fernando J Garcia-Marques et al.
Kathryn L Kapp et al.
Radiation therapy (RT) is a central component of cancer treatment, including breast cancer, and primarily damages DNA in cancer cells, causing cell death. However, secondary effects of RT that may influence tumor and normal tissue both with...
N-Glycan MALDI MSI Differentiates Kidney Glomerular Disease Phenotypes [0.03%]
基于N-聚糖的基质辅助激光解析电离质谱成像鉴别肾小球疾病表型
Aaron O Angerstein,Vishwajeeth Pasham,Caroline Kittrell et al.
Aaron O Angerstein et al.
Lupus nephritis (LN) and diabetic nephropathy (DN) are leading causes of kidney failure, characterized by distinct yet overlapping patterns of glomerular injury. While histopathology remains central to diagnosis, it provides limited insight...
Reference-Free Structure Elucidation of N-O Heterocyclic Ring Systems with Infrared Ion Spectroscopy: A Test Case of the Isoxazoline Insecticide Isocycloseram and Its MS/MS Fragment [0.03%]
无参的N-杂环体系结构解析：以异噁唑啉类杀虫剂异孢菌胺及其碎片为例用红外质子化光谱进行结构阐明
Teun van Wieringen,Agisilaos Chantzis,Jos Oomens et al.
Teun van Wieringen et al.
Five-membered heterocyclic molecules with an N-O bond are emerging as active ingredients in the agrochemical and pharmaceutical industry. Characterization of these molecules in biological matrices is commonly done using liquid chromatograph...
Ambient Pressure Laser Desorption Ionization/Postphotoionization Mass Spectrometry Imaging [0.03%]
大气压激光解吸电离/光电离质谱成像技术
Xiaobo Yao,Liutian Wu,Yaya Wang et al.
Xiaobo Yao et al.
Postphotoionization has been demonstrated to be an effective method to increase the ionization efficiency of laser desorption ionization. In order to scan samples with compact and hard characteristics from the front side, an ambient pressur...
Conformational Landscapes Observed through Controlled Kinetics (CLOCK): Precise Control of Ion Temperatures from Submillisecond to Second Time Scales [0.03%]
通过受控动力学观测构象景观（时钟控制）：从亚毫秒到秒时间尺度精确控制离子温度
AnneClaire Wageman,Yuan Feng,Addison E Roush et al.
AnneClaire Wageman et al.
A detailed understanding of ion conformational dynamics over a range of temperatures and time scales remains a central challenge in structural mass spectrometry. We recently introduced SLIMPHONY, which is a traveling-wave ion mobility (IM) ...
Postblast and Postburn Identification of Forensically Relevant Nitrate Salts as Crown Ether Complexes by Paper Spray Ionization Mass Spectrometry [0.03%]
基于纸喷雾离子化质谱的硝酸盐炸药残渣分析方法研究
Melanie V Tanis,Victoria Servideo,Steven D Letteney et al.
Melanie V Tanis et al.
Ammonium nitrate, along with metal nitrates (including alkali and alkaline earth metal nitrates), is a key oxidizing agent studied in postblast forensics because it is frequently used in explosive mixtures. Herein, the use of crown ether ad...