International expert consensus on the clinical integration of circulating tumor cells in solid tumors [0.03%]
实体瘤国际专家共识：循环肿瘤细胞的临床应用
Eleonora Nicolò,Carolina Reduzzi,Jean-Yves Pierga et al.
Eleonora Nicolò et al.
Background: Circulating tumor cells (CTCs) are a versatile biomarker in solid tumors. Extensive research supports their clinical relevance and led to regulatory approval in breast, prostate, and colorectal cancers. Howeve...
Letter Re: The art of diagnosing rare skin tumors: Can DL-CNNs enhance dermatologists' diagnostic accuracy [0.03%]
关于罕见皮肤肿瘤诊断的艺术：DL-CNN能否提高皮肤病医生的诊断准确性？
Lijun Ye,Wei Zhu,Yan Liang et al.
Lijun Ye et al.
Predicting acute coronary events after breast cancer radiotherapy: Integrating baseline cardiovascular risk, systemic therapy, and cardiac radiation dose in the MEDIRAD BRACE study [0.03%]
MEDIRAD BRACE研究：乳腺癌放疗后预测急性冠脉事件——基线心血管风险、系统性治疗及心脏辐射剂量的综合分析
D S Spoor,N B Boekel,F E V Leeuwen et al.
D S Spoor et al.
Purpose: This study aimed to develop prediction models for acute coronary events (ACE) following breast cancer (BC) radiation therapy (RT). Patients and m...
Clinical outcomes of 3D-total body photography and digital dermoscopy for surveillance of high-risk melanoma patients. A prospective longitudinal observational study [0.03%]
三维全身摄影和数字皮肤镜检查监测高危黑色素瘤患者临床结果的前瞻性纵向观察研究
Laura Serra-García,Gisele Rezze,Ana Claudia Rivas et al.
Laura Serra-García et al.
Introduction: Three-dimensional (3D) total body photography (TBP) offers faster and enhanced skin visualization, potentially improving surveillance of high-risk skin cancer patients. This prospective longitudinal observat...
ENDORISK-2: A personalized Bayesian network for preoperative risk stratification in endometrial cancer, integrating molecular classification and preoperative myometrial invasion assessment [0.03%]
ENDORISK-2：一种个性化的贝叶斯网络，用于子宫内膜癌术前风险分层，结合分子分类和术前肌层浸润评估
Marike S Lombaers,Casper Reijnen,Ally Sprik et al.
Marike S Lombaers et al.
Background: ENDORISK is a Bayesian network that can assist in preoperative risk estimation of lymph node metastasis (LNM) risk in endometrial cancer (EC) with consistent performance in external validations. To reflect sta...
Can NaCl predict or even enhance responses to immunotherapy in cancer? [0.03%]
NaCl能否预测甚至增强癌症免疫治疗的反应？
Jonas Saal,Michael Hölzel,Niklas Klümper
Jonas Saal
The advent of immune checkpoint blockers (ICB) has transformed cancer treatment, but reliable predictive biomarkers remain limited. Emerging evidence suggests that sodium chloride (NaCl) modulates immune responses and may synergize with ICB...
Patient-reported outcomes with paclitaxel and ramucirumab switch maintenance in advanced gastroesophageal cancer: A secondary endpoint of the ARMANI phase 3 trial [0.03%]
一项关于晚期胃食管癌患者在接受多西他赛和ramucirumab转换维持治疗后的结局：ARMANI三期临床试验的次要终点指标分析
Eleonora Cristarella,Margherita Ambrosini,Massimo Di Maio et al.
Eleonora Cristarella et al.
Background: In the ARMANI trial, switch maintenance with paclitaxel plus ramucirumab improved progression-free survival and overall survival versus continuation of oxaliplatin-based chemotherapy in patients with HER2-nega...
Cutaneous squamous cell carcinoma 1986-2019 in Germany: Incidence, anatomical site, staging, and histologic subtypes [0.03%]
1986-2019年德国皮肤鳞状细胞癌的发病率、解剖部位、分期和组织学亚型
Julius Balkenhol,Thomas Dirschka,Conrad Falkenberg et al.
Julius Balkenhol et al.
Background: Cutaneous squamous cell carcinoma (cSCC) is the second most common non-melanoma skin cancer. Population-based data analysis in Germany has largely focused on incidence. Recently analysed datasets covered 4,75 ...
Potential alternative dosage strategies for patent-protected oral cancer drugs [0.03%]
专利保护的口服抗癌药物的潜在替代剂量策略
Austin Wesevich,Liam J Schmitt,Mark J Ratain
Austin Wesevich
Purpose: To identify potential alternative dosage strategies for patent-protected oral oncology drugs that could reduce costs without decreasing efficacy for future post-marketing optimization trials or immediate prescrib...