International phase IV field study to validate the European Organisation for Research and Treatment of Cancer questionnaire for assessing the health-related quality of life of cancer survivors: The EORTC QLQ-SURV100 [0.03%]
国际第四期多中心临床研究验证欧洲癌症研究与治疗组织制定的肿瘤幸存者生活质量测定量表:EORTC QLQ-SURV100
Louis Fox,Marieke van Leeuwen,Jennifer M Jones et al.
Louis Fox et al.
Introduction: Cancer survivors face unique and persistent health-related quality of life (HRQoL) challenges. Existing HRQoL questionnaires for survivors lack content regarding chronic physical issues and have typically in...
Francesca Poggio,Daniele Generali
Francesca Poggio
Results of the ASCENT-03 trial demonstrated a statistically significant improvement in progression-free survival with sacituzumab govitecan (SG) compared with chemotherapy in patients with previously untreated metastatic triple-negative bre...
Time-dependent recurrence patterns after curative resection for stage II/III colorectal cancer: An integrated analysis of four phase III randomized controlled trials (JCOG2310A-S4) [0.03%]
根治性切除II/III期结直肠癌患者的术后复发模式:四项三期随机对照临床试验的整合分析(JCOG2310A-S4)
Keita Tashiro,Hiroki Osumi,Kozo Kataoka et al.
Keita Tashiro et al.
Background: Postoperative surveillance for colorectal cancer (CRC) remains largely uniform despite potentially time-dependent recurrence hazards. Understanding temporal recurrence dynamics may help refine surveillance str...
Validation of the lung immune prognostic index in extensive-stage small cell lung cancer: Post hoc analysis of the caspian and IMpower133 phase 3 trials [0.03%]
肺癌免疫预后指数在广泛期小细胞肺癌中的验证:CASPIAN和IMpower133三期试验的事后分析
Edouard Auclin,Matthieu Roulleaux Dugage,Teresa Gorría et al.
Edouard Auclin et al.
Background: The Lung Immune Prognostic Index (LIPI) is an inflammation-based biomarker associated with outcomes to immunotherapy across several tumor types. Its prognostic value in extensive-stage small-cell lung cancer (...
Temporal linguistic shifts in oncology randomized controlled trials following large language model availability: A corpus analysis of 21,392 publications [0.03%]
大型语言模型出现后肿瘤学随机对照试验中的 temporal linguistic shifts 变化:对 21,392 篇论文的语料库分析
Amina Silva,Vanessa Silva E Silva
Amina Silva
Background: Public availability of large language models (LLMs) from late 2022 has raised concerns about AI-assisted writing in scientific publishing. Oncology randomized controlled trials (RCTs) underpin cancer treatment...
Development and feasibility of the AO spinal metastasis staging (SMS) referral tool: An international multidisciplinary expert panel and survey study [0.03%]
AO脊柱转移瘤分期(SMS)转诊工具的开发和可行性研究:一项国际多学科专家小组和调查研究报告
R Harmen Kuijten,Roxanne Gal,Olivier Q Groot et al.
R Harmen Kuijten et al.
Purpose: Spinal metastases may progress to debilitating pain, spinal instability, and neurological deficits. Timely referral is essential, yet delays are common because patients often first present to non-spine clinicians...
Letter Re: "Progression risk among responders to PD-1/PD-L1 blockade is primarily stratified by response depth" [0.03%]
关于"PD-1/PD-L1抑制剂治疗应答者的疾病进展风险主要取决于应答程度"一文的回信
Xuejiao Fan,Na Li
Xuejiao Fan
The impact of lower household income and distance to hospital on treatment and survival in patients with localized pancreatic adenocarcinoma [0.03%]
家庭收入较低和就诊距离对局部胰腺癌患者治疗及生存的影响分析
Nanske C Biesma,Lois A Daamen,Marc G Besselink et al.
Nanske C Biesma et al.
Introduction: Socialdeprivation, which is exaggerated by lower household income, shortens life expectancy and worsens cancer survival. In pancreatic adenocarcinoma, novel treatment strategies aim to extend survival and ce...
Plasma infrared molecular fingerprinting for prostate cancer detection: Prospective evidence for a partially PSA-independent signal [0.03%]
等离子红外分子指纹用于前列腺癌检测:部分PSA独立信号的前瞻性证据
Philip Jacob,Michael Chaloupka,Tarek Eissa et al.
Philip Jacob et al.
Background: Prostate-specific antigen (PSA) testing has limited specificity, particularly at intermediate concentrations, contributing to diagnostic uncertainty in prostate cancer (PCa). Infrared molecular fingerprinting ...
Patterns of endpoint use in oncology pragmatic clinical trials: A review of randomised studies [0.03%]
肿瘤学务实临床试验的终点使用模式:随机对照研究的系统综述
Christopher Cronin,Fabio Cardoso Borges,Murielle E Mauer et al.
Christopher Cronin et al.
Background: Pragmatic clinical trials (PCTs) aim to address the effectiveness of interventions when applied under conditions which reflect real-world practice. In oncology, PCTs are increasingly used to address research q...