Cemiplimab versus historical systemic treatments for locally advanced or metastatic cutaneous squamous cell carcinomas: Results from the French study TOSCA [0.03%]
塞米匹利玛 vs 历史上用于局部晚期或转移性皮肤鳞状细胞癌的全身治疗方法:来自法国TOSCA研究的结果
Caroline Robert,Emilie Gérard,Emilie Lanoy et al.
Caroline Robert et al.
Background: Cemiplimab an anti-programmed cell death receptor-1 antibody, was approved by the FDA and EMA for patients with locally advanced cutaneous squamous cell carcinoma (laCSCC) ineligible for curative surgery/radio...
Quantifying preferences for watch-and-wait compared with surgery after a clinical complete response in locally advanced rectal cancer: A discrete choice experiment (PrefCoRe) [0.03%]
评估临床完全缓解的局部晚期直肠癌患者接受观察等待与手术的倾向性选择:一项析因调查研究(PrefCoRe)
Garima Dalal,Stuart J Wright,Lee Malcomson et al.
Garima Dalal et al.
Background: Watch-and-wait (W&W) has emerged as an alternative to major surgery for locally advanced rectal cancer in patients with a clinical complete response (cCR) after neoadjuvant chemoradiotherapy. Evidence on prefe...
Impact of gut microbiota on hepatocellular carcinoma: Pathogenesis, diagnosis, prognosis, and therapeutic prospective [0.03%]
肠道菌群对肝细胞癌的影响:发病机制、诊断、预后和治疗前景
Qunwei Chen,Xinyan Feng,Jingxian Wang et al.
Qunwei Chen et al.
Advances in sequencing technology have elucidated the complex role of the gut microbiota in hepatocellular carcinoma (HCC). Communication between the gut and the liver occurs via the gut-liver axis, and dysbiosis of the gut microbiota has b...
Salvatore Vaccarella,Mengmeng Li,Anssi Auvinen et al.
Salvatore Vaccarella et al.
Eva Berardi,Willemien J van Driel,Ralph H M Hermans et al.
Eva Berardi et al.
Background: For patients with advanced ovarian cancer, complete cytoreductive surgery (CRS) offers the best chance for long-term survival and cure. Currently, staging relies on CT and, in selected cases, diagnostic laparo...
Pretherapeutic prognostic factors for survival under chemoimmunotherapy/immunotherapy of advanced NSCLC patients [0.03%]
晚期NSCLC患者进行化疗免疫治疗/免疫治疗的预后生存预测因素分析
Julija Judickiene,Martin Metzenmacher,Gregor Zaun et al.
Julija Judickiene et al.
Background: Checkpoint inhibitor therapy with PD-1/PD-L1-antibodies has significant benefits in non-small-cell lung cancer treatment even in advanced stage IVA/B. While PD-L1 expression in tumor is a weak but relevant pre...
Is pathological complete response a surrogate for overall survival in neoadjuvant clinical trials for gastroesophageal adenocarcinoma? [0.03%]
新辅助临床试验中,病理性完全缓解能否作为胃食管腺癌总体生存期的替代指标?
Luís Felipe Leite,Mariana Macambira Noronha,Samuel Menezes et al.
Luís Felipe Leite et al.
Background: Pathologic complete response (pCR) is frequently used as a surrogate endpoint in neoadjuvant gastroesophageal adenocarcinoma (GEA) trials, yet its validity in predicting overall survival (OS) remains uncertain...
Corrigendum to: "Health-related quality of life of Multiple Endocrine Neoplasia type 1 patients: A mixed methods systematic review" [Eur J Cancer, Vol. 227, 9 September 2025, 115671] [0.03%]
关于“混合方法系统性回顾:1型多发内分泌瘤患者的健康相关生活质量”的勘误说明[Eur J Cancer, Vol. 227, 2025年9月, 115671]
Vignon Salomé,Journé Antoine,Lepage Côme et al.
Vignon Salomé et al.
Long-term cervical cancer risk following negative hrHPV-based versus negative cytology-based screening: A population-based study [0.03%]
基于HR-HPV与细胞学筛查阴性的宫颈癌长期发病风险:一项基于人群的研究
Veerle J C Schevenhoven,Erik E L Jansen,Albert G Siebers et al.
Veerle J C Schevenhoven et al.
Background: Randomized trials have shown that hrHPV-testing provides better protection against cervical cancer than cytology. However, long-term assessment of programme sensitivity remains essential. In the Netherlands, h...
Optic neuropathies induced by immune checkpoint inhibitors: A case series and systematic review of the literature [0.03%]
免疫检查点抑制剂诱导的视神经病变:病例系列和文献系统回顾
Stefania Cuzzubbo,Alberto Vogrig,Evelaine Louis et al.
Stefania Cuzzubbo et al.
Introduction: Immune checkpoint inhibitor (ICI)-related optic neuritis is rare but clinically significant as visual sequelae are reported in around half of affected patients. ...