The telomerase vaccine UV1 combined with ipilimumab and nivolumab versus ipilimumab and nivolumab in advanced melanoma (INITIUM): A randomized open-label phase 2 study [0.03%]
特异性针对端粒酶的疫苗UV1 联合依匹珠单抗和纳武利尤单抗对比依匹珠单抗和纳武利尤单抗治疗晚期黑色素瘤患者：一项开放性Ⅱ期临床研究（INITIUM）
Paul Lorigan,Theresa Michelle Medina,Marta Nyakas et al.
Paul Lorigan et al.
Purpose: Immune checkpoint inhibitor (ICI) combinations have improved outcomes in patients with advanced melanoma; however, long term survival remains poor. The addition of therapeutic cancer vaccines to ICI combinations ...
Pierre Sesques,Guillaume Manson,Sydney Dubois et al.
Pierre Sesques et al.
The management of large B-cell lymphomas (LBCL) has undergone major changes over the last 5 years. These changes reflect the availability of new therapies (immunotherapies, cell therapies, targeted molecules), but also a better compartmenta...
Prediction of HER2 changes post-neoadjuvant therapy based on fusion of ultrasound radiomics and clinicopathological features empowered by explainable AI: A multicenter study [0.03%]
基于融合超声影像组学和临床病理特征的解释型人工智能预测新辅助治疗后HER2改变：一项多中心研究
Yuqi Yan,Xinzheng Xue,Jiayu Xie et al.
Yuqi Yan et al.
Background: Dynamic HER2 expression changes during neoadjuvant therapy (NAT) challenge precision oncology. Current biopsy-dependent evaluation inadequately meets clinical needs for dynamic monitoring. We developed a non-i...
Response to letter Re: Tarlatamab-induced immune-related adverse events: Real-world pharmacovigilance study using the FAERS database [0.03%]
塔拉塔马巴诱导的免疫相关不良事件：使用FAERS数据库进行的真实世界药物警戒研究答复函
Nikhil Vojjala,Prakash Neupane,Nausheen Ahmed
Nikhil Vojjala
A scalable natural language processing framework for drug repurposing in chemotherapy-induced adverse events from clinical narrative records [0.03%]
一种可扩展的自然语言处理框架：从临床叙述记录中对化疗引起的不良事件进行药物再定位
Masami Tsuchiya,Mari Inoue,Yoshimasa Kawazoe et al.
Masami Tsuchiya et al.
Background: Preventing chemotherapy-related adverse events (AEs) remains an unmet clinical challenge. Preclinical studies have suggested protective effects of several existing agents, but translation into human evidence h...
Letter Re: Tarlatamab-induced immune-related adverse events: Real-world pharmacovigilance study using the FAERS database [0.03%]
关于Tarlatamab引起的免疫相关不良事件的信函：使用FAERS数据库进行的真实世界药物警戒研究
Emanuel Raschi,Charles Khouri,Elisabetta Poluzzi et al.
Emanuel Raschi et al.
Damien Roos-Weil,Cécile Tomowiak,Stéphanie Poulain et al.
Damien Roos-Weil et al.
Waldenström's macroglobulinemia (WM) is a rare, indolent B-cell lymphoma that predominantly affects older adults. In recent years, significant progress has been made in understanding its pathogenesis, identifying relevant biomarkers, and d...
Trends in organ preservation in rectal cancer management: A population-based study in the Netherlands [0.03%]
荷兰直肠癌治疗中器官保存趋势的基于人群的研究
A Darai,S de Vries,G L Beets et al.
A Darai et al.
Introduction: This population-based study aims to provide an overview of organ preservation (OP) trends in rectal cancer treatment in the Netherlands. Mat...
Successful treatment of durvalumab-induced psoriasis in an HBV-positive lung cancer patient with Risankizumab: A novel case report [0.03%]
利巴韦林诱导的白细胞减少症的治疗：新的病例报告
Davide Fattore,Francesca Futura Bernardi,Gianluca Esposito et al.
Davide Fattore et al.
Beyond conventional images: AI-driven biotechnologies for oral cancer diagnosis - a systematic review [0.03%]
超越传统影像：口腔癌诊断的人工智能驱动生物技术——系统评价文章
Yimin Wang,Changan Chen,Yiwei Gao et al.
Yimin Wang et al.
Oral cancer (OC) represents a significant global health challenge, with traditional imaging techniques often falling short in early diagnosis. Recent advancements combining artificial intelligence (AI) and biotechnology have led to more acc...