Corrigendum to "Optimization and aerodynamic performance of nebulizable pirfenidone-loaded human serum albumin nanoparticles for targeted pulmonary delivery" [European Journal of Pharmaceutical Sciences 220 (2026) 107477] [0.03%]
关于“用于靶向肺递送的含人血清白蛋白纳米颗粒的优化及气雾化 pirfenidone 的空气动力学性能”的勘误(第 220 卷，2021 年，107477)
Jia-Yu Liu,I-Ling Chen,Meng-Hsuan Cheng et al.
Jia-Yu Liu et al.
CD44-targeted cyclodextrin-hyaluronic acid nanoparticles carrying gemcitabine and paclitaxel to pancreatic cancer [0.03%]
针对胰腺癌的CD44靶向环糊精透明质酸纳米颗粒载吉西他滨和紫杉醇治疗
Gamze Varan,Nurbanu Demirtürk,Sibel Gökşen et al.
Gamze Varan et al.
Pancreatic cancer remains one of the fatal malignancies due to its aggressive nature, late diagnosis, and poor responsiveness to conventional chemotherapy. Overcoming drug resistance and enhancing tumor-specific drug delivery are key challe...
Manufacturing of PSMA-T4 radiopharmaceutical kit for 99mTc labelling as an investigational medicinal product - considerations regarding compliance with GMP [0.03%]
作为 Investigational Medicinal Product（ Investigational Medicinal Product）的99mTC标记用PSMA-T4放射药盒的制造符合GMP规定的考量
Barbara Janota,Marcin Radzik,Agnieszka Sawicka et al.
Barbara Janota et al.
Prostate-specific membrane antigen (PSMA) is overexpressed in both primary and metastatic prostate cancer, making it a promising target for molecular imaging and therapy. The newly developed [99mTc]Tc-PSMA-T4 is an attractive alternative to...
A pH‑responsive hairpin antisense oligonucleotide prodrug system based on the i‑motif for controlled release and enhanced In Vitro antitumor activity in MYCN-amplified cells [0.03%]
基于i-基序的pH响应型发夹反义寡核苷酸前药系统在MYCN扩增细胞中实现可控释放和增强的体外抗肿瘤活性
Zhe Zhang,Zuyi Chen,Yujie Lu et al.
Zhe Zhang et al.
Antisense oligonucleotides (ASOs) have emerged as a powerful therapeutic modality for targeting disease‑associated RNAs. However, most clinical ASOs rely on chemical modifications to enhance stability and pharmacokinetic properties. In thi...
Chagasin-based carriers designed for the cancer-targeted release of proteases [0.03%]
基于香豆素的运载工具用于癌症靶向丝氨酸蛋白酶释放
Jyotsna Jai,Yiling Liu,Xiao Han et al.
Jyotsna Jai et al.
Current methods of targeted disease therapy using cytotoxic enzymes are often administered in their activated form. To allow for a better safety profile, it would be beneficial to have cancer-responsive elements that can promote site-select...
Surrogate-based LC-MS/MS quantification of endogenous creatinine in plasma, plasma-equivalent dried spots (qDPS), and volumetric absorptive microsampling (VAMS): an ICH M10-compliant bridging study [0.03%]
基于替代品的LC-MS/MS量化血浆、等效干点样(qDPS)和体积吸收式微采样(VAMS)中的内源性肌酐：符合ICH M10的桥接研究
Arkadiusz Kocur,Mateusz Moczulski,Paulina Michalczuk et al.
Arkadiusz Kocur et al.
Creatinine quantification in biological matrices remains analytically challenging due to its endogenous presence, which precludes the use of conventional external calibration methods. Concurrently, microsampling techniques such as plasma-eq...
Continuous 3D printing of medicines via a directly coupled twin-screw hot-melt extrusion printing system [0.03%]
连续3D打印药物的双螺杆熔融挤出印刷系统方法
Arne Blume,Stefan Klinken-Uth,Jannis Niesbach et al.
Arne Blume et al.
3D printing drug formulations for personalized medicine is a growing research field and offers many opportunities to improve patient therapy. Downsides of pharmaceutical 3D printing include increased manufacturing costs, lower throughput, p...
PET/MRI with 89Zr-labelled antibodies provides insights into altered antibody pharmacokinetics in the chick embryo model [0.03%]
基于鸡胚胎模型的89Zr标记抗体正电子磁共振成像可提供改变的抗体药代动力学的新见解
Katarína Benčurová,Daniel Gündel,Markus Kieler et al.
Katarína Benčurová et al.
The fertilised chicken egg (in ovo) is a promising, ethically acceptable intermediate model for preselection of radiotracers prior to testing in rodents. The behaviour of monoclonal antibodies in ovo for application in positron emission tom...
Sustainable Chemistry and Preclinical Characterization of RC-106·HCl: A Brain-Penetrant Pan Sigma Receptor Modulator for Glioblastoma [0.03%]
可持续化学和临床前特征测定的RC-106·HCl：一种穿透大脑的Sigma受体泛调制器用于胶质母细胞瘤
Noemi Marino,Roberta Listro,Chiara Milanese et al.
Noemi Marino et al.
RC-106 is a Sigma receptor modulator under investigation as a potential therapeutic agent for glioblastoma (GBM). Here, we report a multigram-scale synthesis based on green chemistry principles, its comprehensive solid-state characterizatio...
Retraction notice to "Vaginal suppositories of cumin seeds essential oil for treatment of vaginal candidiasis: Formulation, in vitro, in vivo, and clinical evaluation" [European Journal of Pharmaceutical Sciences 157 (2021)105602] [0.03%]
关于“采用体外、体内及临床评价研制Cumyn种子精油阴道栓用于治疗阴道念珠菌病”一文的撤稿声明([欧洲药学科学杂志](https://doi.org/10.1016/j.ejps.2021.105602))
Noura H Abd Ellah,Asmaa S Shaltout,Shreen M M Abd El Aziz et al.
Noura H Abd Ellah et al.