Corrigendum to "Circulating plasma exosomal miR-146b-5p regulates microglial-mediated neuroinflammation through the TRAF6/NF-κB signaling axis after intracerebral hemorrhage" [Life Sci. 382 (2025) 124023] [0.03%]
关于“脑出血后循环血浆外泌体miR-146b-5p通过TRAF6/NF-κB信号轴调节小胶质细胞介导的神经炎症”一文的勘误[Life Sci. 382 (2025) 124023]
Fuan Zhang,Chong Han,Jiao Chen et al.
Fuan Zhang et al.
Published Erratum
Life sciences. 2026 Aug 8:124621. DOI:10.1016/j.lfs.2026.124621 2026
SARS-CoV-2 nucleocapsid protein drives pulmonary injury by enhancing GRP75-dependent ER-mitochondria tethering and reprogramming of alveolar macrophages [0.03%]
SARS-CoV-2核蛋白通过增强GRP75依赖的内质网-线粒体连接和肺泡巨噬细胞重编程驱动肺损伤
Ruoxi Zang,Yichao Ren,Jiangmei Wang et al.
Ruoxi Zang et al.
Aims: To determine whether the SARS-CoV-2 nucleocapsid (N) protein promotes lung injury by augmenting GRP75-dependent endoplasmic reticulum (ER)-mitochondria tethering and reprogramming alveolar macrophages (AMϕs). ...
MiR-485-5p targets RGS4 to promote angiogenesis in lower limb ischemia by activating VEGFR-2/AKT/ERK1/2 signaling [0.03%]
MiR-485-5p通过激活VEGFR-2/AKT/ERK1/2信号促进缺血下肢血管生成中靶向调节RGS4的作用
Mengting Li,Yulin Luo,Yufei Li et al.
Mengting Li et al.
Angiogenesis is critical for post-ischemic tissue repair. Although miR-485-5p is highly expressed in vascular tissues and RGS4 regulates angiogenesis, their specific roles under hypoxia remain largely unknown. This study aimed to elucidate ...
Calpain-2 inhibition prevents pressure overload-induced lysosomal cathepsin release and cardiac hypertrophy [0.03%]
钙蛋白酶-2抑制可防止压力超负荷诱导的溶酶体半胱氨酸蛋白酶释放和心室肥大
Anna Martí-Boltaina,David Aluja,Sara Delgado-Tomás et al.
Anna Martí-Boltaina et al.
Aims: Dysregulated calpains and cathepsins contribute to adverse cardiac remodeling following chronic pathological stress, but their interplay and the specific contributions of the classical calpain isoforms remain undefi...
Organelle contact sites as spatial regulators of lipid fate in adipose tissue metabolic disease [0.03%]
线粒体和内质网接触部位通过影响脂滴命运调节代谢疾病中的脂肪组织重塑
Yiqin Yan,Lupeng Chen
Yiqin Yan
Adipose tissue protects metabolic homeostasis by storing excess fatty acids, releasing fuels during energy demand and coordinating endocrine and inflammatory signals. These functions are often described as linear pathways of lipogenesis, li...
NR4A1 negatively regulates ferroptosis of pancreatic β-cells induced by Erastin [0.03%]
NR4A1通过抑制泛素-蛋白酶体系统负向调节胰岛β细胞铁死亡
Wenfei Guo,Mingze Song,Yuhui Wang et al.
Wenfei Guo et al.
Aims: Ferroptosis caused by metabolic stress is a main contributor to pancreatic β-cell injury in type 2 diabetes. Orphan nuclear receptor NR4A1 can be activated by various stimuli and stressors, but its role remains unc...
Rapamycin-sensitive mTORC1 signaling in the medial prefrontal cortex contributes to the antidepressant-like behavioral effects of shikimic acid in mice [0.03%]
没食子酸通过海马mTOR信号通路参与小鼠抗抑郁作用的表观遗传机制研究
Satoshi Deyama,Kana Ito-Shintai,Rinako Sugie et al.
Satoshi Deyama et al.
Aims: Major depressive disorder (MDD) represents a major contributor to disability, yet currently prescribed monoamine-based antidepressants are limited by modest therapeutic efficacy and delayed clinical onset. Recent st...
CCL28 ameliorates chronic liver damage associated with the recruitment of immunosuppressive IgA antibody-secreting cells in mice [0.03%]
CCL28通过招募免疫抑制性IgA抗体分泌细胞改善小鼠慢性肝损伤
Yuta Hara,Masamitsu Bando,Shunya Hosokawa et al.
Yuta Hara et al.
Aims: CCL28 functions as a key chemoattractant for IgA antibody-secreting cells (IgA+ ASCs) and is crucial for maintaining mucosal immune defense. Recent research has revealed IgA+ ASCs with immunosuppressive activity in ...
Slc26a9 guards gastric mucosa against portal hypertension by reducing ER stress-induced apoptosis [0.03%]
SLC26A9通过减少内质网应激诱导的细胞凋亡来保护胃粘膜免受门脉高压损害
Zhiyuan Ma,Zhiqiang Yi,Bei Ji et al.
Zhiyuan Ma et al.
Background: Slc26a9 is a member of the Slc26a family that is highly expressed in the stomach and is a key regulator for maintaining gastric mucosal homeostasis. Slc26a9 deletion in mice impairs the gastric mucosal barrier...
Gut microbiome composition in Huntington's disease: Stage-dependent differences between premanifest and manifest patients [0.03%]
亨廷顿舞蹈病患者的肠道微生物组组成：无症状期和显症期患者存在阶段依赖性差异
Lucía Simón-Vicente,María Ortega Lafont,María Andrés Franch et al.
Lucía Simón-Vicente et al.
Background: Huntington's disease (HD) is a progressive neurodegenerative disorder with substantial clinical heterogeneity. The gut microbiome has been proposed as a potential modulator of neurodegeneration, but its role i...