Jingyue Jia
Jingyue Jia
Lysosomes are membrane-bound organelles that orchestrate a wide range of cellular processes, including degradation, metabolism, signaling, gene regulation and quality control, while interacting with other organelles, thereby profoundly shap...
Gabriela Sobral
Gabriela Sobral
Turtles are unique among living vertebrates in that their body is protected by a shell, but what the first turtle looked like has remained controversial. A new study reappraises the status of Eunotosaurus - the iconic 'missing link' in turt...
Tor D Wager
Tor D Wager
A new study provides the most comprehensive, mechanistic account to date of how the brain learns to predict and mimic drug effects. After associating morphine injections with a place context, the context alone elicits endogenous opioid rele...
Cell morphogenesis: Generalizable control principles from a peculiar protist [0.03%]
细胞形态发生：来自一种奇特原生动物的可推广控制原则
Caitlin Doyle,Ben T Larson
Caitlin Doyle
Cellular form and function are inextricably linked. Close integration of experiment and theory in the intensive study of a suctorian ciliate reveals generalizable regulatory principles for precisely yet adaptively controlling the size and n...
Kinga Kocsis,Michael A Long
Kinga Kocsis
Alston's singing mouse has emerged as an intriguing model for the comparative study of vocal control. New work on the species sets the stage to understand the proximate mechanisms and evolutionary roots of novel acoustic communication trait...
Robert J Huebner
Robert J Huebner
3D analyses of epithelial cells are burdensome, leading many researchers to use highly effective 2D approximations of morphogenesis. A new study approaches mouse hair placode morphogenesis in its 3D totality and reveals important features t...
R Dyche Mullins
R Dyche Mullins
Molecules in the cytoplasm of an animal cell move by diffusion, motor activity, and/or fluid flow. A recent study demonstrates how directed, but often subtle, cytoplasmic drift currents carry cytoskeletal components to the leading edge of c...
Cynthia M Solek,Edward S Ruthazer
Cynthia M Solek
The retina performs visual feature extraction, conveying information to the brain via axonal labeled lines that encode distinct features. A new study reveals surprisingly late developmental plasticity of retinal feature tuning, challenging ...
Fabio Cortesi
Fabio Cortesi
Artificial light at night is a rapidly increasing global pollutant that alters physiology and behaviour in many animals. A new study combining acute-lab and chronic-field exposure now reveals how keeping the lights on disrupts sleep, brain ...
Angelo Forli,Krishna Chaitanya Kasuba,Katharine M Henn et al.
Angelo Forli et al.
Frame-based fluorescence imaging has long defined how neural activity is optically measured1. Yet, this approach relies on acquiring all pixels regardless of their dynamics, intrinsically coupling spatial and temporal resolution while incre...