Federica Invrea,Roberta Rovito,Erica Torchiaro et al.
Federica Invrea et al.
Patient-derived xenografts (PDXs) are obtained by transplanting fragments of a patient's tumour into immunodeficient mice. Growth and propagation of PDXs allows correlating therapeutic response in vivo with extensive, multi-dimensional mole...
Jocelyne Tremouillaux-Guiller,Khaled Moustafa,Kathleen Hefferon et al.
Jocelyne Tremouillaux-Guiller et al.
Millions of people around the world suffer from heavy social and health burdens related to HIV/AIDS and its associated opportunistic infections. To reduce these burdens, preventive and therapeutic vaccines are required. Effective HIV vaccin...
Combining omics technologies with CRISPR-based genome editing to study food microbes [0.03%]
结合CRISPR基因组编辑技术研究食品微生物的多组学技术
Meichen Pan,Rodolphe Barrangou
Meichen Pan
The implementation of omics technologies such as genomics, proteomics and transcriptomics has revolutionized our understanding of microbiomes, and shed light on the functional attributes and mechanisms of action underlying the ability of pr...
Jongmin Kim,Elisa Franco
Jongmin Kim
We review recent advances in the design and expression of synthetic RNA sequences inside cells, to regulate gene expression and to achieve spatial localization of components. We focus on approaches that exploit the programmability of the se...
Jason S Kahn,Brian Minevich,Oleg Gang
Jason S Kahn
Bacillus spore awakening: recent discoveries and technological developments [0.03%]
芽胞杆菌休眠孢子觉醒：近期发现和科技发展
Yun Xing,Willie F Harper Jr
Yun Xing
Elucidating the mechanistic basis of spore germination and outgrowth remains a difficult challenge with crucial implications in the numerous scientific and engineering disciplines. Omics studies have revealed numerous new biochemical insigh...
Recent advances in single cell protein use as a feed ingredient in aquaculture [0.03%]
单细胞蛋白在水产养殖中的最新进展作为饲料成分
Shawn W Jones,Alon Karpol,Sivan Friedman et al.
Shawn W Jones et al.
The global demand for high-quality, protein-rich foods will continue to increase as the global population grows, along with income levels. Aquaculture is poised to help fulfill some of this demand, and is thus the fastest growing animal pro...
Engineering triacylglycerol production from sugars in oleaginous yeasts [0.03%]
利用产油酵母菌株由糖类合成三酰基甘油的研究进展
Annapurna Kamineni,Joe Shaw
Annapurna Kamineni
Oleaginous yeasts natively produce surplus triacylglycerol lipid and can be engineered for higher yield and productivity. Most enzymatic steps of triacylglycerol production are characterized, but key parts of the pathway remain unknown. Thi...
Samuel M Rothstein,Swastik Sen,Thomas J Mansell
Samuel M Rothstein
Lactic acid bacteria play a vital role as starter cultures in the fermentation of a variety of foods, often altering the flavor and texture in addition to aiding in preservation. Their importance to the industry has made them targets for me...
Jong-Won Lee,Cong T Trinh
Jong-Won Lee
Esters constitute a large space of unique molecules with broad range of applications as flavors, fragrances, pharmaceuticals, cosmetics, green solvents, and advanced biofuels. Global demand of natural esters in food, household cleaner, pers...