Ignacio Poblete-Castro,Sarah-Lisa Hoffmann,Judith Becker et al.
Ignacio Poblete-Castro et al.
Sustainable production from seaweed has grown into an area of intense research and development. Meanwhile, more than 30 million tonnes of seaweed are produced, of which 70% are used as food and 30% have other applications such as feed, fert...
New frontiers: harnessing pivotal advances in microbial engineering for the biosynthesis of plant-derived terpenoids [0.03%]
新前沿：利用微生物工程的关键进展进行植物衍生倍半萜生物合成
Michael S Belcher,Jessica Mahinthakumar,Jay D Keasling
Michael S Belcher
Terpenoids are a vast and diverse class of molecules with industrial and medicinal importance. The majority of these molecules are produced across kingdom Plantae via specialized metabolism. Microorganisms, mainly Escherichia coli and Sacch...
Editorial overview: Causes and biotechnological application of microbial metabolic specialization [0.03%]
导语：微生物代谢专化的成因及生物技术应用
David R Johnson,Stephan Noack
David R Johnson
All systems go: converging synthetic biology and combinatorial treatment for CAR-T cell therapy [0.03%]
系统齐备：“合成生物学”与“组合疗法”汇聚推动CAR-T细胞治疗技术
Evripidis Lanitis,George Coukos,Melita Irving
Evripidis Lanitis
Synthetic biology has been transformative to the treatment of advanced hematological malignancies by chimeric antigen receptor (CAR)-engineered T cells. A range of obstacles are now understood to limit the responses of solid epithelial-deri...
Current state of aromatics production using yeast: achievements and challenges [0.03%]
利用酵母生产芳烃的现状：成就与挑战
Quanli Liu,Yi Liu,Yun Chen et al.
Quanli Liu et al.
Aromatics find a range of applications in the chemical, food, cosmetic and pharmaceutical industries. While production of aromatics on the current market heavily relies on petroleum-derived chemical processes or direct extraction from plant...
Dynamics in redox metabolism, from stoichiometry towards kinetics [0.03%]
从计量学角度向动力学角度分析氧化还原代谢的动态变化过程
Koen Ja Verhagen,Walter M van Gulik,Sebastian Aljoscha Wahl
Koen Ja Verhagen
Redox metabolism plays an essential role in the central metabolic network of all living cells, connecting, but at the same time separating, catabolic and anabolic pathways. Redox metabolism is inherently linked to the excretion of overflow ...
Chakradhar Yakkala,Alban Denys,Lana Kandalaft et al.
Chakradhar Yakkala et al.
Cryoablation is a hypothermic modality exercised as a focal therapy for annihilating cancer lesions. Its application leaves the ablated tumor in situ, allowing multifarious tumor antigens to be available to the host's immune system. This en...
Molecular mechanisms of probiotic prevention of antibiotic-associated diarrhea [0.03%]
益生菌预防抗生素相关性腹泻的分子机制
Solomon A Mekonnen,Daniel Merenstein,Claire M Fraser et al.
Solomon A Mekonnen et al.
Antibiotic-associated diarrhea (AAD) is a common and unintended adverse effect of antibiotic treatment. It is characterized by the disruption of the gut microbiota, decreased intestinal short chain fatty acid (SCFA) concentrations, accumula...
Can exascale computing and explainable artificial intelligence applied to plant biology deliver on the United Nations sustainable development goals? [0.03%]
利用exascale计算和可解释的人工智能促进植物生物学以实现联合国可持续发展目标的可能性
Jared Streich,Jonathon Romero,João Gabriel Felipe Machado Gazolla et al.
Jared Streich et al.
Human population growth and accelerated climate change necessitate agricultural improvements using designer crop ideotypes (idealized plants that can grow in niche environments). Diverse and highly skilled research groups must integrate eff...
RNA-based fluorescent biosensors for live cell imaging of small molecules and RNAs [0.03%]
用于活细胞中小分子和RNA成像的基于RNA的荧光生物传感器
Yichi Su,Ming C Hammond
Yichi Su
Genetically encodable fluorescent biosensors provide spatiotemporal information on their target analytes in a label-free manner, which has enabled the study of cell biology and signaling in living cells. Over the past three decades, fueled ...