Electroporation as a method of choice to generate genetically modified dendritic cell cancer vaccines [0.03%]
电穿孔作为生成树突状细胞癌症疫苗的首选方法
Rita Ahmed,Naya Sayegh,Michele Graciotti et al.
Rita Ahmed et al.
In the last few decades, immunotherapy has emerged as an alternative therapeutic approach to treat cancer. Immunotherapy offers a plethora of different treatment possibilities. Among these, dendritic cell (DC)-based cancer vaccines constitu...
In Jin Cho,Kyeong Rok Choi,Sang Yup Lee
In Jin Cho
Microbial production of fatty acids and derivatives from non-edible biomass has attracted much attention as an alternative to their production from plant oils and animal fats. Fatty acids and some of their derivatives are ubiquitous metabol...
Mark Blenner,Jan-Peter van Pijkeren
Mark Blenner
Ralf Reski,Ed Rybicki,Gary Foster
Ralf Reski
Advancements in 13C isotope tracking of synergistic substrate co-utilization in Pseudomonas species and implications for biotechnology applications [0.03%]
用于假单胞菌属的13C同位素示踪技术在协同底物共利用方面的进展及其对生物技术应用的影响
Caroll M Mendonca,Rebecca A Wilkes,Ludmilla Aristilde
Caroll M Mendonca
Pseudomonads are well-known to thrive in diverse and complex nutritional habitats, and these capabilities make Pseudomonas species attractive as whole-cell biocatalysts. Industrial bioconversion processes often rely on complex uptake and sy...
Anupama Yadav,Marc Vidal,Katja Luck
Anupama Yadav
Genetic variants are often not predictive of the phenotypic outcome. Individuals carrying the same pathogenic variant, associated with Mendelian or complex disease, can manifest to different extents, from severe-to-mild to no disease. Impro...
Microbial production of extremolytes - high-value active ingredients for nutrition, health care, and well-being [0.03%]
极端条件微生物产物在营养、健康和保健中的应用及产业化前景
Judith Becker,Christoph Wittmann
Judith Becker
Extremolytes are small organic molecules, which protect cells under extreme, virtually inhabitable conditions. Their exceptional properties can be translated into health-promoting and therapeutic activities, which open an avenue of opportun...
Shanmuga Reddy Chilakapati,Jason Ricciuti,Emese Zsiros
Shanmuga Reddy Chilakapati
Immunomodulation has become a promising and growing field of cancer research. Compelling results from a variety of studies provide strong evidence for the importance of commensal bacteria on oncologic outcomes and response to antitumor immu...
Microfluidic platforms for the dynamic characterisation of synthetic circuitry [0.03%]
用于合成线路动态表征的微流控平台
Tim Prangemeier,François-Xavier Lehr,Rogier M Schoeman et al.
Tim Prangemeier et al.
Generating novel functionality from well characterised synthetic parts and modules lies at the heart of synthetic biology. Ideally, circuitry is rationally designed in silico with quantitatively predictive models to predetermined design spe...
Discovery of CC bond-forming and bond-breaking radical enzymes: enabling transformations for metabolic engineering [0.03%]
碳碳键形成和断裂自由基酶的发现：代谢工程转化反应的新突破
Beverly Fu,Emily P Balskus
Beverly Fu
Radical enzymes catalyze some of the most chemically challenging CC bond-forming and bond-breaking reactions. Advances in DNA sequencing have accelerated the discovery of radical enzymes from microbes, including radical S-adenosylmethionine...