Combination therapy strategies targeting glypican-3 in hepatocellular carcinoma: A comprehensive review [0.03%]
肝癌中靶向Glypican-3的联合治疗策略:全面综述
Sina Nabiyi,Mohammad Heiat,Ehsan Rezaei
Sina Nabiyi
Hepatocellular carcinoma (HCC) remains a leading cause of cancer-related mortality worldwide. Advanced disease often proves resistant to conventional therapies, thereby driving the intensive search for targeted therapies. Glypican-3 (GPC3),...
Dimitrios G Argyris,Lillian Johnson,Thomas Hägglöf et al.
Dimitrios G Argyris et al.
CXCL13, a chemokine originally identified for its role in B-cell trafficking, signals through the G-protein-coupled receptor CXCR5, to organize germinal centers and maintain immune architecture in secondary lymphoid organs. Beyond its physi...
Meteorin-like/Metrnl: A pleiotropic cytokine implicated in metabolic, inflammatory and malignant disorders [0.03%]
Meteorin样蛋白/Metrnl:一种参与代谢、炎症和恶性疾病的多功能细胞因子
Jinlian Li,Pei Ye,Jingli Si et al.
Jinlian Li et al.
Metrnl, a secreted protein highly expressed in adipocytes, endothelial cells, muscle cells, and activated macrophages, has been identified as a novel myokine and adipokine. It plays important roles in enhancing white fat browning, improving...
Role of anti-tumorigenic cytokines in gastrointestinal cancers [0.03%]
细胞因子在胃肠肿瘤中的抗肿瘤作用机制及临床应用前景研究进展
Olivia Hooks,Lily T Childers,Justin T Childers et al.
Olivia Hooks et al.
Gastrointestinal (GI) cancers are among the deadliest worldwide, with millions of cases and deaths annually. In the U.S., they account for over 25 % of cancer-related deaths, with colorectal cancer (CRC) leading in incidence and mortality, ...
Biological macromolecule-driven therapeutics in rheumatoid arthritis: Integrating drug delivery, regenerative medicine, and orthopedic repair [0.03%]
类风湿关节炎的生物大分子驱动疗法:药物输送、再生医学与骨科修复的整合
Jun-Ze Tang,Lin Feng,Ting-Ting Liu et al.
Jun-Ze Tang et al.
Rheumatoid arthritis (RA) is a chronic autoimmune disease affecting 0.5-1 % of the global population, leading to joint destruction, disability, and high socioeconomic costs. While conventional therapies like DMARDs and biologics have improv...
The IL-17 axis in gastric carcinogenesis: From inflammation to oncogenic transformation [0.03%]
胃癌发生发展中的IL-17轴:从炎症到致癌转化
Zhaojie Lyu,Mancang Gu,Zhengmao Lu et al.
Zhaojie Lyu et al.
Gastric cancer (GC) remains a leading cause of global cancer mortality, with Helicobacter pylori (Hp)-induced chronic inflammation and immune dysregulation playing a central pathogenic role. This review consolidates current understanding of...
Post COVID-19 pandemic Inflammatory Insights into Cancer: Consequences for immunotherapy [0.03%]
新冠肺炎疫情后的炎症视域与癌症免疫治疗的相互作用及影响
Carla Eksteen,Lé-Chandré Asja,Atarah Rass et al.
Carla Eksteen et al.
The COVID-19 pandemic has reshaped the landscape of global health, revealing novel interactions between infectious diseases and chronic conditions such as cancer. Beyond acute infection, growing evidence suggests that persistent exposure to...
Begüm Coşar,Pelin Kılıç,Özlem Darcansoy İşeri
Begüm Coşar
Chimeric antigen receptor (CAR) T-cell (CAR-T) therapy is a transformative modality in cancer immunotherapy that employs genetically engineered T-cells to eliminate malignant cells selectively. Its efficacy and limitations are governed by c...
Inflammation and Type 1 interferon signaling in pancreatic adenocarcinoma: Insights into inflammasome driven crosstalk and therapeutic advances [0.03%]
胰腺癌中的炎症和I型干扰素信号:关于炎性体介导的相互作用及治疗进展的见解
Spyridoula D Katsarou,Maria Panagopoulou,Stavroula Baritaki
Spyridoula D Katsarou
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and lethal malignancies, characterized by a profoundly immunosuppressive and inflammatory tumor microenvironment (TME). Chronic pancreatic inflammation not only driv...
Corrigendum to "Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy" [Cytokine Growth Factor Rev. 84 (2025) 59-73] [0.03%]
关于“免疫细胞中铁死亡:对肿瘤免疫和癌症治疗的意义”的勘误(细胞因子生长因子 Rev. 84 (2025) 59-73)
Jianbo Gao,Xiaoling Zhang,Yue Liu et al.
Jianbo Gao et al.
Published Erratum
Cytokine & growth factor reviews. 2025 Nov 26:87:1. DOI:10.1016/j.cytogfr.2025.11.004 2025