Begüm Coşar,Pelin Kılıç,Özlem Darcansoy İşeri
Begüm Coşar
Chimeric antigen receptor (CAR) T-cell (CAR-T) therapy is a transformative modality in cancer immunotherapy that employs genetically engineered T-cells to eliminate malignant cells selectively. Its efficacy and limitations are governed by c...
Inflammation and Type 1 interferon signaling in pancreatic adenocarcinoma: Insights into inflammasome driven crosstalk and therapeutic advances [0.03%]
胰腺癌中的炎症和I型干扰素信号：关于炎性体介导的相互作用及治疗进展的见解
Spyridoula D Katsarou,Maria Panagopoulou,Stavroula Baritaki
Spyridoula D Katsarou
Pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive and lethal malignancies, characterized by a profoundly immunosuppressive and inflammatory tumor microenvironment (TME). Chronic pancreatic inflammation not only driv...
Corrigendum to "Ferroptosis in immune cells: Implications for tumor immunity and cancer therapy" [Cytokine Growth Factor Rev. 84 (2025) 59-73] [0.03%]
关于“免疫细胞中铁死亡：对肿瘤免疫和癌症治疗的意义”的勘误(细胞因子生长因子 Rev. 84 (2025) 59-73)
Jianbo Gao,Xiaoling Zhang,Yu&#x;e Liu et al.
Jianbo Gao et al.
Published Erratum
Cytokine & growth factor reviews. 2025 Nov 26:87:1. DOI:10.1016/j.cytogfr.2025.11.004 2025
Nanotechnology-based cytokine delivery strategies in gastrointestinal cancers [0.03%]
基于纳米技术的细胞因子在胃肠癌症中的传递策略
Jonaid Ahmad Malik,Madeeha Khan,Umme Hani et al.
Jonaid Ahmad Malik et al.
Gastrointestinal (GI) cancers, including colorectal, gastric, and esophageal malignancies, remain a major global health burden, with high incidence and mortality despite advances in diagnostics and conventional therapies. Cytokine-based imm...
Dhana Sekhar Reddy Bandi,Siva Chander Chabattula,Hasitha Pynam et al.
Dhana Sekhar Reddy Bandi et al.
Pancreatic ductal adenocarcinoma (PDAC) contains various cell types scattered by desmoplastic stroma and communicate through small molecular weight signaling molecules called cytokines. Cytokines include interleukins, chemokines, interferon...
Natural killers or natural regulators? Dual roles of NK cells in checkpoint immunotherapy [0.03%]
自然杀伤细胞的双重角色：免疫治疗的“双刃剑”
Wenxue Ma,Sheldon Morris,Catriona Jamieson
Wenxue Ma
Natural killer (NK) cells have long been recognized as central antitumor effectors capable of eliminating transformed cells without prior sensitization. However, recent studies reveal a more nuanced reality: NK cells can also act as regulat...
NK cell adaptation in the tumor microenvironment: Insights for NK cell-based immunotherapy [0.03%]
肿瘤微环境中NK细胞的适应性：基于NK细胞免疫疗法的新见解
Yaopeng Li,Yan Gao,Liangliang Wang et al.
Yaopeng Li et al.
Natural killer (NK) cells serve as critical first responders within the immune system, orchestrating antitumor responses by directly eliminating malignant cells and modulating broader immune functions. Their capacity to recognize stressed t...
SARS-CoV-2 innate immune recognition and implications for respiratory health [0.03%]
SARS-CoV-2的先天免疫识别及其对呼吸健康的影响
Vandana Anang,Pankaj Kumar,Jamaluddin Pracha et al.
Vandana Anang et al.
The ongoing global health impact of SARS-CoV-2, particularly on lung and respiratory health, underscores the critical need to decipher the intricate interplay between the virus and the host innate immune system. This review provides an anal...
Role of cytokine-based immunotherapy approaches in gastrointestinal cancers [0.03%]
细胞因子介导的免疫疗法在胃肠道肿瘤的应用及挑战
Rafik ElBeblawy,Midhun Malla,Mehmet Akce
Rafik ElBeblawy
Gastrointestinal (GI) cancers are among the most common leading causes of cancer-related mortality globally and they are the leading cause of cancer-related mortality in the US. Immune checkpoint inhibitor (ICI)-based therapies altered trea...
Targeting the colony-stimulating factor 1 axis for the treatment of Tenosynovial Giant Cell Tumors [0.03%]
靶向集落刺激因子1轴治疗滑膜巨细胞瘤
Paul Humbert,Charlotte Vialle,Marie Chevalerias et al.
Paul Humbert et al.
Diffuse and Localized Tenosynovial Giant Cell Tumors (D-/L-TGCT) are two closely related forms of benign tumors of the joint characterized by uncontrolled macrophage infiltration and proliferation. Both forms arise from similar translocatio...