LC3B: A microtubule-associated protein influences disease progression and prognosis [0.03%]
LC3B：一种微管相关蛋白影响疾病的进展和预后
Yan Chen,Hong Yi,Shan Liao et al.
Yan Chen et al.
Microtubule-associated protein 1 light chain 3B (MAP1LC3B, also known as LC3B) is a mammalian homolog of the autophagy-related protein 8 (ATG8) family. It plays a crucial role in cellular autophagy and is involved in several vital biologica...
Cytokine signalling in formation of neutrophil extracellular traps: Implications for health and diseases [0.03%]
细胞因子信号在中性粒细胞胞外陷阱形成中的作用：对健康和疾病的启示
Haritha Manoj,Sarah Michael Gomes,Pooja Yedehalli Thimmappa et al.
Haritha Manoj et al.
Neutrophils, as essential component of the innate immune response, form a crucial part in the defence mechanisms through the release of extracellular traps (NETs). These web-like structures, composed of chromatin and antimicrobial proteins,...
IL-33 in cancer immunotherapy: Pleiotropic functions and biological strategies [0.03%]
白细胞介素33在癌症免疫治疗中的多效功能及生物策略
Keying Che,Jinyu Li,Zheng Chen et al.
Keying Che et al.
Interleukin-33 (IL-33) belongs to the IL-1 cytokine superfamily and plays a critical role in regulating immune responses and maintaining host homeostasis. IL-33 is essential for driving and enhancing type 2 immune responses and is closely a...
Cytokine modulation and immunoregulation of uterine NK cells in pregnancy disorders [0.03%]
细胞因子调节和子宫自然杀伤细胞免疫调控在妊娠疾病中的作用
Jun Zhou,Ping Yan,Wenxue Ma et al.
Jun Zhou et al.
Uterine natural killer (uNK) cells play a pivotal role in promoting placental development and supporting maternal-fetal immune tolerance, primarily through cytokine regulation and growth factor production. While the importance of uNK cells ...
The activin-follistatin system: Key regulator of kidney development, regeneration, inflammation, and fibrosis [0.03%]
活化素-抗活化素系统：肾脏发育、再生、炎症和纤维化的关键调节因子
Izumi Nagayama,Yoshinori Takei,Shunsuke Takahashi et al.
Izumi Nagayama et al.
Activins, multifunctional cytokines of the transforming growth factor-beta superfamily, play critical roles in the regulation of growth and differentiation in multiple biological systems. Activin activity is finely regulated by the endogeno...
Cholecystokinin and gastrin as immune modulating hormones: Implications and applications [0.03%]
作为免疫调节激素的胆囊收缩素和胃泌素：意义及应用
Gustav van Niekerk,Lara Kelchtermans,Elias Broeckhoven et al.
Gustav van Niekerk et al.
Cholecystokinin (CCK) and gastrin are gastrointestinal hormones traditionally recognised for their roles in digestion. However, it has been recognised that these hormones may also modulate immune function. Here, we examine the immune-modula...
Kewei Liu,Linyi Zhou,Meihui Shi et al.
Kewei Liu et al.
Vitiligo, a disorder marked by hypopigmentation, significantly impacts patients' quality of life and mental health. This condition results from the reduction or dysfunction of melanocytes, which are crucial for skin and hair pigmentation. C...
Logan S Dean,Alissa N Threatt,Kaylee Jones et al.
Logan S Dean et al.
Defense of the human body against damaging and pathogenic insults is a heavily regulated affair. A primary mechanism of defense at sites of insult are soluble mediators whose defensive maneuvers increase barrier integrity and promote pro-re...
Glioblastoma-associated macrophages: A key target in overcoming glioblastoma therapeutic resistance [0.03%]
胶质母细胞瘤相关巨噬细胞：克服胶质母细胞瘤治疗耐药性的关键靶点
Aymane Kricha,Najat Bouchmaa,Sanae Ben Mkaddem et al.
Aymane Kricha et al.
Glioblastoma multiforme (GBM) is recognized as the most aggressive and malignant form of brain cancer, characterized by a highly heterogeneous phenotype, poor prognosis, and a median survival time of less than 16 months. Recent studies have...
Suprabhat Mukherjee,Jagadeesh Bayry
Suprabhat Mukherjee
Various pattern recognition receptors (PRRs), including toll-like receptors (TLRs), play a crucial role in recognizing invading pathogens as well as damage-associated molecular patterns (DAMPs) released in response to infection. The resulti...