The distinct C-terminal acidic domains of HMGB proteins are functionally relevant in Schistosoma mansoni [0.03%]
酸性尾域对Schistosoma mansoni组蛋白结合蛋白HMGB的功能具有重要意义
Isabel Caetano de Abreu da Silva,Vitor Coutinho Carneiro,Amanda Roberta Revoredo Vicentino et al.
Isabel Caetano de Abreu da Silva et al.
The Schistosoma mansoni High Mobility Group Box (HMGB) proteins SmHMGB1, SmHMGB2 and SmHMGB3 share highly conserved HMG box DNA binding domains but have significantly different C-terminal acidic tails. Here, we used three full-length and ta...
Amblyomma sculptum tick saliva: α-Gal identification, antibody response and possible association with red meat allergy in Brazil [0.03%]
巴西 Amblyomma sculptum 蜱唾液中的α-半乳糖的鉴定、抗体反应及其与红肉过敏的关系研究
Ricardo Nascimento Araujo,Paula Ferreira Franco,Henrique Rodrigues et al.
Ricardo Nascimento Araujo et al.
The anaphylaxis response is frequently associated with food allergies, representing a significant public health hazard. Recently, exposure to tick bites and production of specific IgE against α-galactosyl (α-Gal)-containing epitopes has b...
Hemozoin is a product of heme detoxification in the gut of the most medically important species of the family Opisthorchiidae [0.03%]
血红素解毒产物ヘモゾイン是医学上最重要的肝吸虫科物种肠道中的产物
Maria Lvova,Mariya Zhukova,Elena Kiseleva et al.
Maria Lvova et al.
Many species of trematodes such as Schistosoma spp., Fasciola hepatica and Echinostoma trivolvis are blood-feeding parasites. Nevertheless, there is no consensus on the feeding habits of the family Opisthorchiidae (Opisthorchis felineus, Op...
Characterising granuloma regression and liver recovery in a murine model of schistosomiasis japonica [0.03%]
日本血吸虫病小鼠模型中肉芽肿消退和肝脏恢复的特征研究
Candy Chuah,Malcolm K Jones,Donald P McManus et al.
Candy Chuah et al.
For hepatic schistosomiasis the egg-induced granulomatous response and the development of extensive fibrosis are the main pathologies. We used a Schistosoma japonicum-infected mouse model to characterise the multi-cellular pathways associat...
Robert Poulin
Robert Poulin
The species richness of freshwater environments is disproportionately high compared with that of the oceans, given their respective sizes. If diversification rates are higher in freshwaters because they are isolated and heterogeneous, this ...
Protein kinase A signalling in Schistosoma mansoni cercariae and schistosomules [0.03%]
壳有螺期曼氏血吸虫和童期虫体中的蛋白激酶A信号转导途径
Natasha L Hirst,Scott P Lawton,Anthony J Walker
Natasha L Hirst
Cyclic AMP (cAMP)-dependent protein kinase/protein kinase A regulates multiple processes in eukaryotes by phosphorylating diverse cellular substrates, including metabolic and signalling enzymes, ion channels and transcription factors. Here ...
Technical advances in trigger-induced RNA interference gene silencing in the parasite Entamoeba histolytica [0.03%]
应用于溶组织内阿米巴的诱导型RNA干扰技术及其应用进展
Mohamed I Khalil,Bardees M Foda,Susmitha Suresh et al.
Mohamed I Khalil et al.
Entamoeba histolytica has a robust endogenous RNA interference (RNAi) pathway. There are abundant 27 nucleotide (nt) anti-sense small RNAs (AS sRNAs) that target genes for silencing and the genome encodes many genes involved in the RNAi pat...
Oxidative stress-mediated mouse liver lesions caused by Clonorchis sinensis infection [0.03%]
氧化应激介导的肝吸虫感染所致的小鼠肝脏损伤
Sejung Maeng,Hye Won Lee,Qudsia Bashir et al.
Sejung Maeng et al.
Clonorchis sinensis is a high-risk pathogenic helminth that strongly provokes inflammation, epithelial hyperplasia, periductal fibrosis, and even cholangiocarcinoma in chronically infected individuals. Chronic inflammation is associated wit...
The more the merrier--experimental evidence for density-dependent feeding facilitation in the bird-specialised tick Ixodes arboricola [0.03%]
越多越好——鸟类专性栖寄蜱Ixodes arboricola释放密度制约的摄食促进的实证研究
A R Van Oosten,E Matthysen,D J A Heylen
A R Van Oosten
Similar to many other parasites, the distribution of ticks among hosts is strongly skewed, with few hosts harbouring the majority of parasites. Because parasite-induced impairment of host health, parasite population growth and pathogen tran...
Molecular phylogeny and systematics of the Echinostomatoidea Looss, 1899 (Platyhelminthes: Digenea) [0.03%]
后螠目的分子系统发育与分类(Echinostomatoidea Looss, 1899)(扁形动物门：吸虫纲)
Vasyl V Tkach,Olena Kudlai,Aneta Kostadinova
Vasyl V Tkach
The Echinostomatoidea is a large, cosmopolitan group of digeneans currently including nine families and 105 genera, the vast majority parasitic, as adults, in birds with relatively few taxa parasitising mammals, reptiles and, exceptionally,...