The ROP18 and ROP5 gene allele types are highly predictive of virulence in mice across globally distributed strains of Toxoplasma gondii [0.03%]
在全球分布的毒隐抱子虫株中,ROP18和ROP5基因等位类型可高度预测小鼠模型中的致病性
Elliot Keats Shwab,Tiantian Jiang,Hilda F J Pena et al.
Elliot Keats Shwab et al.
The protozoan parasite Toxoplasma gondii is one of the most successful known eukaryotic pathogens on Earth. Virulence of T. gondii strains varies greatly in mice, and mounting evidence suggests that such variations may be relevant to the ma...
Novel O-linked methylated glycan antigens decorate secreted immunodominant glycoproteins from the intestinal nematode Heligmosomoides polygyrus [0.03%]
新型O-甲基化糖链抗原修饰肠道线虫Heligmosomoides polygyrus分泌的主导免疫糖蛋白分子
James P Hewitson,D Linh Nguyen,Angela van Diepen et al.
James P Hewitson et al.
Glycan molecules from helminth parasites have been associated with diverse biological functions ranging from interactions with neighbouring host cell populations to down-modulation of specific host immunity. Glycoproteins secreted by the in...
Reaction norms of host immunity, host fitness and parasite performance in a mouse--intestinal nematode interaction [0.03%]
小鼠和寄生线虫相互作用中的宿主免疫反应、宿主适应性及病原表现型反应规范研究
Cédric Lippens,Emmanuel Guivier,Bruno Faivre et al.
Cédric Lippens et al.
The outcome of the encounter between a host and a parasite depends on the synergistic effects of the genetics of the two partners and the environment (sensulato) where the interaction takes place. Reaction norms can depict how host and para...
Transcriptome analysis of stress tolerance in entomopathogenic nematodes of the genus Steinernema [0.03%]
应用于耐受性昆虫病原体线虫的转录组分析
Mor Yaari,Adi Doron-Faigenboim,Hinanit Koltai et al.
Mor Yaari et al.
Entomopathogenic nematodes of the genus Steinernema are effective biological control agents. The infective stage of these parasites can withstand environmental stresses such as desiccation and heat, but the molecular and physiological mecha...
Genotypic variation in host response to infection affects parasite reproductive rate [0.03%]
宿主感染反应的基因型差异影响寄生虫繁殖率
Hannah F Tavalire,Michael S Blouin,Michelle L Steinauer
Hannah F Tavalire
Parasite fitness is largely influenced by a variation in host response due to the host's genetic background. Here we investigated the impact of host genotype on pathogen success in the snail vector of its castrating parasite, Schistosoma ma...
Trade-offs and resource breadth processes as drivers of performance and specificity in a host-parasite system: a new integrative hypothesis [0.03%]
取舍与资源广度过程驱动宿主-寄生关系性能和特异性的新假说
Rafael B P Pinheiro,Gabriel M F Félix,Anderson V Chaves et al.
Rafael B P Pinheiro et al.
One of the unresolved issues in the ecology of parasites is the relationship between host specificity and performance. Previous studies tested this relationship in different systems and obtained all possible outcomes. This led to the propos...
Estimating mRNA lengths from Plasmodium falciparum genes by Virtual Northern RNA-seq analysis [0.03%]
利用Virtual Northern RNA测序分析法估计恶性疟原虫基因的mRNA长度
Philip J Shaw,Pavita Kaewprommal,Jittima Piriyapongsa et al.
Philip J Shaw et al.
Accurate gene models are essential for understanding parasite biology. However, transcript structure information is lacking for most parasite genes. Here, we describe "Virtual Northern" analysis of the malaria parasite Plasmodium falciparum...
Exposure to double-stranded RNA mediated by tobacco rattle virus leads to transcription up-regulation of effector gene Mi-vap-2 from Meloidogyne incognita and promotion of pathogenicity in progeny [0.03%]
烟草环斑病毒介导的双链RNA暴露诱导根结线虫效应子Mi-VAP-2表达并促进其后代致病性增强
Yuankai Chi,Xuan Wang,Xiuhu Le et al.
Yuankai Chi et al.
Meloidogyne spp. are economically important plant parasites and cause enormous damage to agriculture world-wide. These nematodes use secreted effectors which modify host cells, allowing them to obtain the nutrients required for growth and d...
Entomopathogenic and plant pathogenic nematodes as opposing forces in agriculture [0.03%]
在农业生产中对立的虫生和植物寄生线虫
Eric Kenney,Ioannis Eleftherianos
Eric Kenney
Plant-parasitic nematodes are responsible for substantial damages within the agriculture industry every year, which is a challenge that has thus far gone largely unimpeded. Chemical nematicides have been employed with varying degrees of suc...
Detecting and quantifying parasite-induced host mortality from intensity data: method comparisons and limitations [0.03%]
利用强度数据检测和量化寄生虫引起的宿主死亡：方法比较与局限性
Mark Q Wilber,Sara B Weinstein,Cheryl J Briggs
Mark Q Wilber
Parasites can significantly impact animal populations by changing host behaviour, reproduction and survival. Detecting and quantifying these impacts is critical for understanding disease dynamics and managing wild animal populations. Howeve...