Multi-scale occupancy approach to estimate Toxoplasma gondii prevalence and detection probability in tissues: an application and guide for field sampling [0.03%]
多尺度占域模型估计组织中弓形虫的感染率及检测概率：来自实际数据的应用与示例
Stacey A Elmore,Kathryn P Huyvaert,Larissa L Bailey et al.
Stacey A Elmore et al.
Increasingly, birds are recognised as important hosts for the ubiquitous parasite Toxoplasma gondii, although little experimental evidence exists to determine which tissues should be tested to maximise the detection probability of T. gondii...
Identifying antimalarial compounds targeting dihydrofolate reductase-thymidylate synthase (DHFR-TS) by chemogenomic profiling [0.03%]
基于化学组学筛选抗疟新药研究
Aiyada Aroonsri,Olugbenga Akinola,Navaporn Posayapisit et al.
Aiyada Aroonsri et al.
The mode of action of many antimalarial drugs is unknown. Chemogenomic profiling is a powerful method to address this issue. This experimental approach entails disruption of gene function and phenotypic screening for changes in sensitivity ...
Rafael Ramiro de Assis,Fernanda Ludolf,Rie Nakajima et al.
Rafael Ramiro de Assis et al.
A proteome microarray consisting of 992 Schistosoma mansoni proteins was produced and screened with sera to determine antibody signatures indicative of the clinical stages of schistosomiasis and the identification of subunit vaccine candida...
RNA-seq analysis of early enteromyxosis in turbot (Scophthalmus maximus): new insights into parasite invasion and immune evasion strategies [0.03%]
欧洲扁鱼肠虫病早期的RNA测序分析：寄生虫入侵和免疫逃避策略的新见解
Paolo Ronza,Diego Robledo,Roberto Bermúdez et al.
Paolo Ronza et al.
Enteromyxum scophthalmi, an intestinal myxozoan parasite, is the causative agent of a threatening disease for turbot (Scophthalmus maximus, L.) aquaculture. The colonisation of the digestive tract by this parasite leads to a cachectic syndr...
Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva [0.03%]
限制血清型和基因型的多样性以改进东非动物传染性坏死肝炎活疫苗
Johanneke D Hemmink,William Weir,Niall D MacHugh et al.
Johanneke D Hemmink et al.
An infection and treatment protocol is used to vaccinate cattle against Theileria parva infection. Due to incomplete cross-protection between different parasite isolates, a mixture of three isolates, termed the Muguga cocktail, is used for ...
Independent origins of loss-of-function mutations conferring oxamniquine resistance in a Brazilian schistosome population [0.03%]
巴西血吸虫群中导致奥克曼葵酯抗性的无义突变的独立起源
Frédéric D Chevalier,Winka Le Clec&#x;h,Nina Eng et al.
Frédéric D Chevalier et al.
Molecular surveillance provides a powerful approach to monitoring the resistance status of parasite populations in the field and for understanding resistance evolution. Oxamniquine was used to treat Brazilian schistosomiasis patients (mid-1...
Female genital schistosomiasis (FGS): from case reports to a call for concerted action against this neglected gynaecological disease [0.03%]
女性生殖器血吸虫病（FGS）从个案报告到呼吁对这种被忽视的妇科疾病采取联合行动
Vanessa Christinet,Janis K Lazdins-Helds,J Russell Stothard et al.
Vanessa Christinet et al.
In recent years, control of neglected tropical diseases has been increasingly gaining momentum and interventions against schistosomiasis are being progressively scaled-up through expansion of donated praziquantel and preventive chemotherapy...
J-dot targeting of an exported HSP40 in Plasmodium falciparum-infected erythrocytes [0.03%]
针对疟原虫感染的红细胞中出口的HSP40的J-点靶向作用
Wiebke Petersen,Simone Külzer,Sonja Engels et al.
Wiebke Petersen et al.
Plasmodium falciparum exports a large number of proteins to its host cell, the mature human erythrocyte, where they are involved in host cell modification. Amongst the proteins trafficked to the host cell, many are heat shock protein (HSP)4...
Identification of new markers for the Schistosoma mansoni vitelline lineage [0.03%]
鉴定Schistosoma mansoni卵黄细胞系的新标记物
Jipeng Wang,James J Collins rd
Jipeng Wang
Schistosomes cause significant morbidity and mortality in millions of the world's poorest people. While parasite egg-induced inflammation is the primary driver of host pathology, relatively little is known at the molecular level about the o...
Epigenetic modulation, stress and plasticity in susceptibility of the snail host, Biomphalaria glabrata, to Schistosoma mansoni infection [0.03%]
表观调控、压力和塑料对椎实螺宿主(巴蜗牛)感染斯氏狸殖吸虫的易感性的影响
Matty Knight,Wannaporn Ittiprasert,Halime D Arican-Goktas et al.
Matty Knight et al.
Blood flukes are the causative agent of schistosomiasis - a major neglected tropical disease that remains endemic in numerous countries of the tropics and sub-tropics. During the past decade, a concerted effort has been made to control the ...