Temperature rise and parasitic infection interact to increase the impact of an invasive species [0.03%]
温度升高和寄生感染相互作用加剧入侵物种的影响
Ciaran Laverty,David Brenner,Christopher McIlwaine et al.
Ciaran Laverty et al.
Invasive species often detrimentally impact native biota, e.g. through predation, but predicting such impacts is difficult due to multiple and perhaps interacting abiotic and biotic context dependencies. Higher mean and peak temperatures, t...
Comparative cophylogenetics of Australian phabine pigeons and doves (Aves: Columbidae) and their feather lice (Insecta: Phthiraptera) [0.03%]
澳大利亚phinx pigeon及其羽毛虱的协同系统发生分析（鸟纲：鸠鸽科；昆虫纲：十足目）
Andrew D Sweet,R Terry Chesser,Kevin P Johnson
Andrew D Sweet
Host-parasite coevolutionary histories can differ among multiple groups of parasites associated with the same group of hosts. For example, parasitic wing and body lice (Insecta: Phthiraptera) of New World pigeons and doves (Aves: Columbidae...
Comparative genomic analysis of the IId subtype family of Cryptosporidium parvum [0.03%]
隐孢子虫IId亚型家族的比较基因组分析
Yaoyu Feng,Na Li,Dawn M Roellig et al.
Yaoyu Feng et al.
Host adaptation is known to occur in Cryptosporidium parvum, with IIa and IId subtype families preferentially infecting calves and lambs, respectively. To improve our understanding of the genetic basis of host adaptation in Cryptosporidium ...
Plasmodium berghei plasmepsin VIII is essential for sporozoite gliding motility [0.03%]
恶性疟原虫蛋白酶VIII是裂殖子滑行运动的必需蛋白质
Babu S Mastan,Sunil Kumar Narwal,Sandeep Dey et al.
Babu S Mastan et al.
Plasmodium aspartic proteases, termed plasmepsins (PMs) play many critical roles such as haemoglobin degradation, cleavage of PEXEL proteins and sporozoite development in the parasite life cycle. Most of the plasmepsins are well characteriz...
Factors affecting the distribution of haemosporidian parasites within an oceanic island [0.03%]
影响海洋岛上血孢子虫分布的因素分析
David P Padilla,Juan Carlos Illera,Catalina Gonzalez-Quevedo et al.
David P Padilla et al.
Understanding how different ecological and evolutionary processes influence the distribution of pathogens within the environment is important from many perspectives including wildlife epidemiology, evolutionary ecology and conservation. The...
The genome of the protozoan parasite Cystoisospora suis and a reverse vaccinology approach to identify vaccine candidates [0.03%]
新型疫苗候选标记的发掘——以球囊袋状隐孢子虫基因组序列为研究对象
Nicola Palmieri,Aruna Shrestha,Bärbel Ruttkowski et al.
Nicola Palmieri et al.
Vaccine development targeting protozoan parasites remains challenging, partly due to the complex interactions between these eukaryotes and the host immune system. Reverse vaccinology is a promising approach for direct screening of genome se...
Philip J Shaw,Aiyada Aroonsri
Philip J Shaw
An understanding of the biology of Plasmodium parasites, which are the causative agents of the disease malaria, requires study of gene function. Various reverse genetic tools have been described for determining gene function. These tools ca...
Explaining parasite aggregation: more than one parasite species at a time [0.03%]
论寄生虫的聚集性：同一宿主同时感染多种寄生虫现象的研究
André Morrill,Felipe Dargent,Mark R Forbes
André Morrill
Studies generally have neglected parasite-centric views in explorations of whether the oft-seen patterns of parasite aggregation are adaptive. Using simulation models, we explored the effects of aggregation on coinfection with hetero- or co...
Accelerating the clinical development of protein-based vaccines for malaria by efficient purification using a four amino acid C-terminal 'C-tag' [0.03%]
利用四氨基酸C端标签高效纯化加速疟疾蛋白质疫苗的临床开发研究
Jing Jin,Kathryn A Hjerrild,Sarah E Silk et al.
Jing Jin et al.
Development of bespoke biomanufacturing processes remains a critical bottleneck for translational studies, in particular when modest quantities of a novel product are required for proof-of-concept Phase I/II clinical trials. In these instan...
Wai-Hong Tham,Alyssa Barry,Diana S Hansen et al.
Wai-Hong Tham et al.