A novel ex vivo immunoproteomic approach characterising Fasciola hepatica tegumental antigens identified using immune antibody from resistant sheep [0.03%]
一种新颖的体外免疫蛋白质组学方法表征肝片吸虫护膜抗原并利用抵抗力羊的免疫抗体进行鉴定
Timothy C Cameron,Ira Cooke,Pierre Faou et al.
Timothy C Cameron et al.
A more thorough understanding of the immunological interactions between Fasciola spp. and their hosts is required if we are to develop new immunotherapies to control fasciolosis. Deeper knowledge of the antigens that are the target of the a...
Lungworms and gastrointestinal parasites of domestic cats: a European perspective [0.03%]
欧洲家猫的肺线虫和消化道寄生虫感染状况
Alessio Giannelli,Gioia Capelli,Anja Joachim et al.
Alessio Giannelli et al.
With the exception of Aelurostrongylus abstrusus, feline lungworms have been poorly studied. Information on their distribution is patchy and mostly limited to case reports. In this study, the occurrence of feline lungworms and co-infecting ...
D P Bechtsi,A P Waters
D P Bechtsi
Malaria is the disease caused by the apicomplexan parasites belonging to the genus Plasmodium. Expanding our arsenal to include transmission-blocking agents in our fight against malaria is becoming increasingly important. Such an implementa...
Epigenetic landscapes underlining global patterns of gene expression in the human malaria parasite, Plasmodium falciparum [0.03%]
表观遗传景观决定人疟原虫基因表达的全局模式
Archana P Gupta,Zbynek Bozdech
Archana P Gupta
The dynamic chromatin landscape displaying combinatorial complexity of the epigenome impacts gene expression that underlies many events of differentiation and cell cycle progression. In the past few years, epigenetic mechanisms have emerged...
The unhealthy attraction of Plasmodium vivax to reticulocytes expressing transferrin receptor 1 (CD71) [0.03%]
恶性疟原虫对转铁蛋白受体1(CD71)阳性幼红细胞的趋向性
Benoit Malleret,Laurent Rénia,Bruce Russell
Benoit Malleret
The majority of malaria parasite species prefer to invade reticulocytes, the most infamous being Plasmodium vivax. While the absence of an in vitro continuous culture method has hampered the study of P. vivax invasion biology, studies utili...
Schistosome-induced pulmonary B cells inhibit allergic airway inflammation and display a reduced Th2-driving function [0.03%]
日本血吸虫诱导的肺部B细胞具有抑制过敏性气道炎症及降低Th2功能的作用
L E P M van der Vlugt,K Obieglo,A Ozir-Fazalalikhan et al.
L E P M van der Vlugt et al.
Chronic schistosome infections protect against allergic airway inflammation (AAI) via the induction of IL-10-producing splenic regulatory B (Breg) cells. Previous experiments have demonstrated that schistosome-induced pulmonary B cells can ...
Venestatin, a Ca++-binding protein from the parasitic nematode Strongyloides venezuelensis, is involved in the larval migration process [0.03%]
一种线虫寄生虫中的钙结合蛋白参与了线虫幼虫的迁移过程
Daigo Tsubokawa,Takeshi Hatta,Taisei Kikuchi et al.
Daigo Tsubokawa et al.
The secretory EF-hand Ca++-binding proteins act as calcium signaling molecules for control of cell functions, but those proteins from parasitic helminths are poorly understood. Here, we have identified and characterized an EF-hand Ca++-bind...
Whence river blindness? The domestication of mammals and host-parasite co-evolution in the nematode genus Onchocerca [0.03%]
河盲症的起源？哺乳动物的驯化及寄生虫与宿主在旋尾线虫属内共生进化的影响
Emilie Lefoulon,Alessio Giannelli,Benjamin L Makepeace et al.
Emilie Lefoulon et al.
The genus Onchocerca includes 34 described species and represents one of the largest genera of the filarial nematodes within the family Onchocercidae. Representative members of this genus are mainly parasites of ungulates, with some excepti...
Yesid Cuesta-Astroz,Francislon Silva de Oliveira,Laila Alves Nahum et al.
Yesid Cuesta-Astroz et al.
Helminths cause a number of medical and agricultural problems and are a major cause of parasitic infections in humans, animals and plants. Comparative analysis of helminth genes and genomes are important to understand the genomic biodiversi...
Identification and functional characterization of Oncomelania hupensis macrophage migration inhibitory factor involved in the snail host innate immune response to the parasite Schistosoma japonicum [0.03%]
一种东方螺巨噬细胞迁移抑制因子的鉴定及其对日本血吸虫先天性免疫反应的功能表征
Shuaiqin Huang,Yunchao Cao,Mingke Lu et al.
Shuaiqin Huang et al.
Schistosomiasis, caused by parasitic trematodes of the genus Schistosoma, remains a devastating public health problem, with over 200 million people infected and 779 million people at risk worldwide, especially in developing countries. The f...