Metagenomic next generation sequencing of bronchoalveolar lavage fluids for the identification of pathogens in patients with pulmonary infection: A retrospective study [0.03%]
基于支气管肺泡灌洗液的病原菌宏基因组测序在肺部感染中的诊断价值:回顾性研究
Wenwen Qin,Tai Guo,Tiebin You et al.
Wenwen Qin et al.
Due to the limitations of traditional laboratory methods (TMs), identification of causative pathogens of numerous pulmonary infections (PIs) remains difficult. This study evaluated the value of metagenomic next generation sequencing (mNGS) ...
Exploring the accuracy of third-generation Nanopore Sequencing technology for detecting mycobacterium tuberculosis in patients with diabetes mellitus [0.03%]
探索第三代Nanopore测序技术在糖尿病患者中检测结核分枝杆菌准确性的研究
Chang Song,Chunyan Zhao,Yingxing Nong et al.
Chang Song et al.
Objective: To explore the diagnostic value of third-generation nanopore sequencing technology in patients with diabetes mellitus suspected of pulmonary tuberculosis. ...
Cefazolin inoculum effect in methicillin-susceptible Staphylococcus aureus clinical isolates [0.03%]
头孢唑林对甲氧西林敏感金黄色葡萄球菌临床分离株的接种量效应
Shuma Tsuji,Kazuyoshi Gotoh,Tadahiro Manabe et al.
Shuma Tsuji et al.
We investigated the prevalence and characteristics of Cefazolin inoculum effect (CInE) among clinical MSSA isolates in Japan. Although 35.5 % (39 isolates) were positive for the blaZ gene, none met the phenotypic criteria for CInE. Our find...
In vivo emergence of cefiderocol and ceftazidime/avibactam cross-resistance in KPC-producing Klebsiella pneumoniae following ceftazidime/avibactam -based therapies [0.03%]
美罗培南和阿维巴坦联合治疗后肺炎克雷伯菌耐药性问题的产生:基于一例KPC型肺炎克雷伯菌感染患者的临床分析
Stefano Amadesi,Alberto Amedeo,Matteo Rinaldi et al.
Stefano Amadesi et al.
We described the emergence of ceftazidime/avibactam and cefiderocol cross-resistance in patients with KPC-producing Klebsiella pneumoniae infections. All strains with ceftazidime/avibactam and cefiderocol cross-resistance showed point mutat...
Corrigendum to "Tropheryma whipplei detected by metagenomic next-generation sequencing in bronchoalveolar lavage fluid" [Diagnostic Microbiology and Infectious Disease Volume 109, Issue 4, August 2024, 116374] [0.03%]
关于“通过宏基因组下一代测序在支气管肺泡灌洗液中检测到Tropheryma whipplei”的勘误说明(诊断微生物学与感染病Volume 109, Issue 4, August 2024, 116374)
Lan Min Lai,Xin Yu Zhu,Rui Zhao et al.
Lan Min Lai et al.
Identification of potential biomarkers for sepsis based on neutrophil extracellular trap-related genes [0.03%]
基于中性粒细胞胞外陷阱相关基因的脓毒症潜在生物标志物识别
Jiping Tang,Haijuan Lu,Zuohua Xie et al.
Jiping Tang et al.
Sepsis is a highly lethal disease that poses a serious threat to human health. Increasing evidence indicates that neutrophil extracellular traps (NETs) are key factors in the pathological progression of sepsis. This study aims to screen pot...
Prevalence of Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma urealyticum among outpatients in central China: A retrospective study [0.03%]
中国中部地区门诊患者解脲支原体、沙眼衣原体及淋球菌感染流行病学调查回顾性研究
Shun Liu,Yaoling Ouyang,Quan Tang et al.
Shun Liu et al.
Neisseria gonorrhoeae (NG), Chlamydia trachomatis (CT), Ureaplasma urealyticum (UU) are the common sexually transmitted pathogens and lead to genital diseases, highly prevalent all around the world. The objective of this study was to analyz...
Fracture-associated infection with Mycobacterium smegmatis in a 16-year old patient [0.03%]
一例16岁患者胞壁分枝杆菌(smegmatis)感染致骨折病例报道
Neele J Froböse,Tom Theiler,Dagmar Horn et al.
Neele J Froböse et al.
We present a patient who suffered an agricultural rollover trauma and developed a fracture-associated tissue infection caused by Mycobacterium smegmatis. Since cases are rare, treatment of infections with M. smegmatis requires an interprofe...
A standardized protocol using clinical adjudication to define true infection status in patients presenting to the emergency department with suspected infections and/or sepsis [0.03%]
一种标准化协议,用于临床判断急诊科疑似感染和/或脓毒症患者的真正感染状况
Natalie N Whitfield,Catherine A Hogan,James Chenoweth et al.
Natalie N Whitfield et al.
In absence of a "gold standard", a standardized clinical adjudication process was developed for a registrational trial of a transcriptomic host response (HR) test. Two physicians independently reviewed clinical data to adjudicate presence a...
Genome-based diagnostic of MDR Escherichia coli ONT:H19 ST10955 causing human gastrointestinal infection [0.03%]
基于基因组的诊断多重耐药埃希氏菌ONT:H19 ST10955导致的人体胃肠道感染
Daniel F M Monte,Fabio P Sellera,Nilton Lincopan et al.
Daniel F M Monte et al.
This study focuses on the genomic characterization of a multidrug-resistant Escherichia coli strain responsible for a severe gastrointestinal infection in a 33-year-old male. The patient initially received sulfamethoxazole/trimethoprim trea...