Performance evaluation of the COPAN Colibrí™ instrument for automated identification using the bruker MALDI-TOF Biotyper® and antimicrobial susceptibility testing with the bioMérieux VITEK®2 [0.03%]
COPAN Colibrí™仪器的性能评估：使用布鲁克MALDI-TOF Biotyper®进行自动化鉴定及使用生物梅里埃VITEK®2进行抗菌药物敏感性试验
Jasmine Ahmed-Bentley,Kim Sy,Colleen Fletcher et al.
Jasmine Ahmed-Bentley et al.
The Copan Colibrí™ is FDA approved for preparing MALDI-TOF target plates to identify bacteria and yeast, and for making bacterial suspensions for AST. This study evaluated its performance in automating identification and AST of clinical i...
Comparative and subtractive genomics reveals novel therapeutic targets in cystic fibrosis-associated multidrug-resistant Pandoraea sputorum [0.03%]
比较和减法基因组学揭示了囊性纤维化相关多重耐药潘多拉菌新治疗靶点
Roni Mia,Anandha Mozumder,Anupam Das et al.
Roni Mia et al.
Despite increasing clinical reports of its emergence and multidrug resistance, particularly in cystic fibrosis (CF) patients, comprehensive genomic insights and effective therapeutic strategies targeting P. sputorum remain scarce. This stud...
Influence of different media and incubation times for determining the minimum inhibitory concentrations of gepotidacin, ciprofloxacin and ceftriaxone against Neisseria gonorrhoeae [0.03%]
不同培养基和孵育时间对解脲支原体、人型支原体和沙眼衣原体体外抗菌活性的影响
Laura M Koeth,Jeanna DiFranco-Fisher,Joshua West et al.
Laura M Koeth et al.
Gepotidacin (GSK2140944) is a novel triazaacenaphthylene antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV by a distinct binding site, a unique mechanism of action and has been approved for the treatment of urogenital gonor...
Smart diagnostics: Leveraging artificial intelligence for accurate at-home COVID-19 testing [0.03%]
聪明的诊断方法：利用人工智能实现家用COVID-19测试的准确性
Nathan M Jacob,Paxton H Threatt,Mackenzie L White et al.
Nathan M Jacob et al.
Reverse transcriptase polymerase chain reaction (RT-PCR), the reference standard for COVID-19 diagnosis, is time-consuming, resource-intensive, and costly. Rapid antigen tests address these limitations but rely on visual interpretation, whi...
A U-shaped association between the systemic immune-inflammation index and refractory Mycoplasma pneumoniae pneumonia in children: A retrospective cohort study [0.03%]
系统性免疫炎症指数与儿童难治性肺炎支原体肺炎关系的回顾队列研究
Yanchen Liu,Aifen Huang,Suwan Xiong et al.
Yanchen Liu et al.
Objectives: This study aimed to explore the association between the SII and RMPP incidence, focusing the dose-response relationship to provide new insights into RMPP pathogenesis. ...
Transport of viable representative Enterobacterales species (Klebsiella spp., Escherichia spp., Citrobacter spp., Enterobacter spp., and Cronobacter spp.) at ambient temperature using sterile filter paper [0.03%]
采用无菌滤纸在室温下运输有活力的大肠杆菌目代表性菌种（克雷伯氏菌属、埃希氏菌属、产气肠杆菌属、肠杆菌属和芽单胞菌属）
Mamitina Alain Noah Rabenandrasana,Lala Rafetrarivony,Tina Juliano Ratovoson et al.
Mamitina Alain Noah Rabenandrasana et al.
Objectives: To validate a simple, low-cost protocol for transporting viable Enterobacterales at ambient temperature using sterile filter paper, addressing logistical and financial constraints in resource-limited laborator...
Primary thyroid tuberculosis associated with thyroid dysfunction in a Child: An unexpected diagnosis [0.03%]
与甲状腺功能异常相关的原发性儿童甲状腺结核：意外诊断
Bablu Kumar Gaur,Navya Jain,N S Chithambaram
Bablu Kumar Gaur
Primary thyroid tuberculosis is a rare form of extra-pulmonary tuberculosis, with only a few cases recorded in the literature, and none of which had thyroid dysfunction. A 6-year-old child came to us with complains of fever and neck swellin...
Diagnostic performance of serum galactomannan for detecting breakthrough invasive fungal infections in pediatric hematologic malignancies receiving mold-active prophylaxis [0.03%]
防治用药患儿血液肿瘤患者侵袭性真菌突破感染的血清半乳甘露聚糖检测性能评估
Fatma Ünal,Belgin Gülhan,Saliha Kanık Yüksek et al.
Fatma Ünal et al.
Background: This study aimed to evaluate the diagnostic performance of serum galactomannan for invasive fungal infections in children with hematologic malignancies and to assess the impact of mold-active antifungal prophy...
Comparison of the AccuPower HIV-1 Quant Kit and Aptima HIV-1 Quant Dx Assay for quantification of HIV-1 plasma viral load [0.03%]
安捷普HIV-1核酸定量试剂盒与阿波坦HIV-1 RNA检测试剂比较检测艾滋病患者血浆病毒载量的性能分析
Tae Yeul Kim,Minhee Kang,Hui-Jin Yu et al.
Tae Yeul Kim et al.
HIV-1 viral load testing is essential for monitoring antiretroviral therapy response in HIV-1-infected patients. This study aimed to evaluate the clinical performance of the AccuPower HIV-1 Quant Kit (Bioneer), a newly developed HIV-1 viral...
A practical three-dimensional checkerboard method for triple combinations: Ceftriaxone with cinnamaldehyde and carvacrol in Klebsiella pneumoniae ATCC 10031 [0.03%]
一种用于三元组合的实用三维棋盘格方法：ceftriaxone与香兰醛和百里酚在大肠杆菌肺炎克雷伯氏菌ATCC 10031中的作用研究
Abdulhamit Cali,Rukiye Aslan
Abdulhamit Cali
Objective: Two-dimensional (2D) checkerboard assays are used for dual antimicrobial combinations; however, adding a third agent increases the concentration space to three dimensions, complicating plate layout and reportin...