Development of a chemical precipitated-LAMP assay for the diagnosis of knowlesi malaria [0.03%]
一种用于知道氏疟疾诊断的化学沉淀LAMP检测方法的建立
Meng Yee Lai,Yee Ling Lau
Meng Yee Lai
A visualized air-dried precipitated loop-mediated isothermal amplification (ADP-LAMP) master mix, incorporating hydroxynapthol blue dye, was developed for the detection of Plasmodium knowlesi. The ADP-LAMP assay was designed to overcome the...
Automated implementation of the SwabSeq COVID-19 diagnostic assay on the opentrons flex liquid-handling robot [0.03%]
基于Opentrons Flex液体处理机器人的SwabSeqCOVID-19诊断检测试剂盒的自动化实施
Taryn E Jakub,Varada Abhyankar,Traci Toy et al.
Taryn E Jakub et al.
The SwabSeq COVID-19 diagnostic assay [7] enables scalable SARS-CoV-2 detection using next-generation sequencing (NGS) of barcoded samples without RNA extraction. To adapt this approach for routine clinical use, we developed a fully automat...
Preliminary study investigating the performance of the BACTECTM Mycosis IC/F blood culture system for Malassezia spp. detection [0.03%]
一项关于BACTECTM Mycosis IC/F血培养系统检测马拉色菌种性能的初步研究
Victor Luzarraga,Jean-Etienne Porcheron,Kevin Brunet et al.
Victor Luzarraga et al.
Diagnostic tools for Malassezia bloodstream infections remain limited and incidence of Malassezia spp. bloodstream infections in immunocompromised patients is probably underestimated. We assessed the performance of the BACTECTM Mycosis IC/F...
Proposal for screening cut-off values and use of tolerance disk test (TDtest) for detection of tolerance/persistence to ceftazidime-avibactam in Klebsiella pneumoniae [0.03%]
头孢他啶/阿维巴坦耐药筛查截断值的建议及Klebsiella pneumoniae菌株中头孢他啶/阿维巴坦耐受性/持续性的容忍盘试验检测体系的建立
Nathália Abichabki,Fernando Bellissimo-Rodrigues,Gilberto Gambero Gaspar et al.
Nathália Abichabki et al.
Objective: We aimed to characterize ceftazidime-avibactam (CZA)-tolerant/persistent Klebsiella pneumoniae, previously categorized as CZA-susceptible, and propose screening cut-off values for CZA-tolerance/persistence. Mor...
Cristina Gay González,Irati Arregui García,Jimmy Alonso Madrigal Cruz et al.
Cristina Gay González et al.
Francisella tularensis is an uncommon cause of osteoarticular infection and an exceptionally rare cause of periprosthetic joint infection. Diagnosis may be delayed because clinical suspicion is low and microbiological identification require...
Ines Bartegi,Fatma Hammami,Khaoula Rekik et al.
Ines Bartegi et al.
Background: Mucormycosis is a life-threatening invasive fungal infection that primarily affects immunocompromised individuals, particularly those with poorly controlled diabetes mellitus, hematological malignancies, or so...
When the test lies: Fatal cryptococcosis and the prozone effect in advanced HIV infection [0.03%]
当试验结果出错时：HIV晚期感染患者的隐球菌病与浓度过高现象
Mylene Costa,Patrícia Rodrigues,Beatriz Araújo et al.
Mylene Costa et al.
Cryptococcal meningitis is a life-threatening opportunistic infection in advanced HIV disease. Cryptococcal antigen (CrAg) detection by lateral flow assay (LFA) is the diagnostic cornerstone, offering high sensitivity and specificity. Howev...
Development of RPA and nested-RPA based CRISPR/Cas13a diagnostic platform for the identification of HBV DNA and HCV RNA in Indian patient cohort [0.03%]
基于CRISPR/Cas13a诊断平台的RPA和套嵌式RPA技术在印度患者队列中检测HBV DNA和HCV RNA的发展应用研究
Teja Naveen Sata,Amrendra Kumar Sah,Md Ismail et al.
Teja Naveen Sata et al.
Background: Among the Indian population, hepatitis B virus (HBV) is one of the major burdens and the hepatitis C virus (HCV) chronically infects around 1% Indian population. CRISPR-based detection platforms have shown to ...
Prevalence and genotypic distribution of human papillomavirus in India: Insights from a five-year retrospective laboratory-based study [0.03%]
印度人乳头瘤病毒的流行率和基因型分布：基于五年回顾性实验室的研究见解
Nandagopal Murugan,Venugopal Kalyankumar,Sonai Mukinkumar et al.
Nandagopal Murugan et al.
Background: While several regional and multicenter studies have documented HPV distribution in India, nationally representative large-scale data remain limited. This study evaluated HPV prevalence and genotypic diversity ...
Impact of Helicobacter pylori transformation from bacillary to coccoid form on ureC gene detectability by conventional PCR: A comparative study and in silico analysis [0.03%]
幽门螺杆菌从杆菌型转化为球杆状对其尿素酶基因常规PCR检出率影响的研究及模拟分析
Mohamed Oussi,Aicha Baalala,Fatima Zahra Kheir et al.
Mohamed Oussi et al.
Helicobacter pylori is a bacterium that infects the stomach lining in half of the world's population and is responsible for 1 to 3% of stomach cancer cases. Colonization occurs through various morphologies, including the spiral bacillary an...