Carbon dots-supported Zn single atom nanozymes for the catalytic therapy of diabetic wounds [0.03%]
基于碳点的锌单原子纳米酶用于糖尿病伤口催化治疗
Sheng Dai,Li Yao,Luying Liu et al.
Sheng Dai et al.
Diabetic wound treatment continues to be a significant clinical issue due to higher levels of oxidative stress, susceptibility to bacterial infections, and chronic inflammatory responses during healing. We rationally developed and synthesiz...
Cell volume regulation modulates macrophage-related inflammatory responses via JAK/STAT signaling pathways [0.03%]
细胞体积调节通过JAK/STAT信号通路调控巨噬细胞相关的炎症反应
Xueying Yang,Qifan Wang,Fei Shao et al.
Xueying Yang et al.
Cell volume as a characteristic of changes in response to external environmental cues has been shown to control the fate of stem cells. However, its influence on macrophage behavior and macrophage-mediated inflammatory responses have rarely...
Boron substitution in silicate bioactive glass scaffolds to enhance bone differentiation and regeneration [0.03%]
通过硼掺杂硅酸盐生物活性玻璃支架增强骨细胞分化和再生
Agata Szczodra,Amel Houaoui,Rémy Agniel et al.
Agata Szczodra et al.
Commercially available bioactive glasses (BAGs) are exclusively used in powder form, due to their tendency to crystallize. Silicate BAG 1393 was developed to allow fiber drawing and scaffold sintering, but its slow degradation limits its po...
Comparative study on mechanical properties and biomineralization of hooks in the diaspores of three epizoochorous plant species [0.03%]
三种附生植物种子钩的力学性能与生物矿化机制比较研究
Carla Gensana Claus,Elena V Gorb,Stanislav N Gorb et al.
Carla Gensana Claus et al.
Most of the plants using epizoochory show adaptations to this diaspore dispersal strategy by having the diaspores covered by barbs, hooks, spines or viscid outgrowths, which allow diaspores to easily attach to an animal surface. Many previo...
Comparative Study
Acta biomaterialia. 2024 Sep 15:186:330-341. DOI:10.1016/j.actbio.2024.07.041 2024
Tumor microenvironment-responsive macrophage-mediated immunotherapeutic drug delivery [0.03%]
肿瘤微环境响应的巨噬细胞介导的免疫治疗药物递送系统
Xueyang Zhang,Ludan Yue,Lei Cao et al.
Xueyang Zhang et al.
Immunotherapy, as a promising treatment strategy for cancer, has been widely employed in clinics, while its efficiency is limited by the immunosuppression of tumor microenvironment (TME). Tumor-associate macrophages (TAMs) are the most abun...
Acidic biofilm microenvironment-responsive ROS generation via a protein nanoassembly with hypoxia-relieving and GSH-depleting capabilities for efficient elimination of biofilm bacteria [0.03%]
具备缓解缺氧和耗尽谷胱甘肽能力的蛋白质纳米组装体响应生物膜细菌微环境中的酸性ROS生成以高效消除生物膜细菌
Junqin Li,Mengya Sun,Xiaoxian Tang et al.
Junqin Li et al.
Reactive oxygen species (ROS) are widely considered to the effective therapeutics for fighting bacterial infections especially those associated with biofilm. However, biofilm microenvironments including hypoxia, limited H2O2, and high gluta...
Study of the influence of macro-structure and micro-structure on the mechanical properties of stag beetle upper jaw [0.03%]
大型甲虫上颚的宏微观结构对其力学性能影响的研究
Zhiwei Tuo,Yu Shi,Xianyan Sun et al.
Zhiwei Tuo et al.
Macrostructural control of stress distribution and microstructural influence on crack propagation is one of the strategies for obtaining high mechanical properties in stag beetle upper jaws. The maximum bending fracture force of the stag be...
Zwitterionic-hydrogel-based sensing system enables real-time ROS monitoring for ultra-long hypothermic cell preservation [0.03%]
两性离子水凝胶基传感系统实现细胞超长低溫保存过程中的实时ROS监测
Yunqing Tian,Yiming Ma,Yuxiang Kang et al.
Yunqing Tian et al.
Hypothermic preservation (HP) is highly desired for the maintenance of the viability of living cell specimens, e.g. rare cells in whole-blood samples or therapeutic cells, in an unfrozen state. However, the extension of the viable preservat...
Extracellular matrix regulation of cell spheroid invasion in a 3D bioprinted solid tumor-on-a-chip [0.03%]
基于细胞球侵袭的三维生物打印肿瘤芯片中的基质调控研究
Elvan Dogan,Christopher A Galifi,Berivan Cecen et al.
Elvan Dogan et al.
Tumor organoids and tumors-on-chips can be built by placing patient-derived cells within an engineered extracellular matrix (ECM) for personalized medicine. The engineered ECM influences the tumor response, and understanding the ECM-tumor r...
Bioactive polymer composite scaffolds fabricated from 3D printed negative molds enable bone formation and vascularization [0.03%]
由3D打印负向模具制造的生物活性聚合物复合支架可促进骨组织形成及血管生成
Shengrong Du,Tony Huynh,Yen-Zhen Lu et al.
Shengrong Du et al.
Scaffolds for bone defect treatment should ideally support vascularization and promote bone formation, to facilitate the translation into biomedical device applications. This study presents a novel approach utilizing 3D-printed water-dissol...