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期刊名:Acta biomaterialia

缩写:ACTA BIOMATER

ISSN:1742-7061

e-ISSN:1878-7568

IF/分区:10.4/Q1

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Haiyuan Song,Zhenhua Chao,Qian Guo et al. Haiyuan Song et al.
Collective migration of polyclonal tumor cell clusters is a key driver of efficient cancer metastasis, yet how microscale mechanical heterogeneity within the extracellular matrix (ECM) governs this process remains largely unclear. Here, we ...
Xingyu Tao,Guangyue Zu,Jingcheng Su et al. Xingyu Tao et al.
Extracellular vesicles (EVs) are increasingly recognized as programmable biologics with broad therapeutic potential across diverse diseases. However, their clinical translation is hindered by limited therapeutic efficiency due to poor targe...
Thomas Li,Gabriela Canziani,Yuchen Liu et al. Thomas Li et al.
Cartilage extracellular matrix (ECM), a hydrated collagen II-aggrecan composite, undergoes dynamic turnover during both normal homeostasis and disease-associated remodeling. This study elucidates a crucial role for decorin in promoting the ...
Bingjie Fu,Huidi Meng,Min Liang et al. Bingjie Fu et al.
Pathological scarring following skin trauma remains a formidable clinical challenge. Hydrogel dressings can promote wound closure by providing wet healing environment, yet the role of the dressing's mechanical microenvironment on the scar f...
Sayed Mir Sayed,Zeeshan Tahir,Yavuz Nuri Ertas Sayed Mir Sayed
Multidrug-resistant (MDR) bacterial infections demand antibacterial strategies that circumvent conventional resistance pathways and enable localized action with minimal host toxicity. Photodynamic therapy (PDT) represents a non-invasive app...
Robert Koucheki,Janet Tang,Johnathan R Lex et al. Robert Koucheki et al.
Periprosthetic joint infections (PJIs) are one of the most dreaded complications of arthroplasty. Although relatively rare with an incidence of 1-2%, the absolute burden of PJIs is growing over time as the volume of performed arthroplasties...
Shiqin Peng,Ying Hao,Bo Li et al. Shiqin Peng et al.
Despite guideline-directed reperfusion and pharmacological therapies, myocardial infarction (MI) continues to pose substantial clinical challenges, with high incidence and mortality rates. Mesenchymal stromal cell (MSC) transplantation repr...
Marc Bohner,Nicola Döbelin,Christophe Drouet et al. Marc Bohner et al.
Calcium-deficient hydroxyapatite (CDHA) is a widely studied calcium phosphate biomaterial due to its chemical similarity to bone mineral and its relevance as a bone graft substitute. This review presents a comprehensive analysis of CDHA's s...
Jingyu He,Ziqiao Zhong,Zijian Peng et al. Jingyu He et al.
Vaginal progesterone administration represents the preferred route for luteal phase support in assisted reproductive technology due to the uterine first-pass effect. However, its therapeutic efficacy is limited by poor aqueous solubility an...