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期刊名:Acta biomaterialia

缩写:ACTA BIOMATER

ISSN:1742-7061

e-ISSN:1878-7568

IF/分区:9.6/Q1

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Clinical Trial Case Reports Meta-Analysis RCT Review Systematic Review
Classical Article Case Reports Clinical Study Clinical Trial Clinical Trial Protocol Comment Comparative Study Editorial Guideline Letter Meta-Analysis Multicenter Study Observational Study Randomized Controlled Trial Review Systematic Review
Jiahua Ni,Wenhui Wang,Haidong Xu et al. Jiahua Ni et al.
The commonly used closing clips do not fully meet clinical requirements. For instance, non-degradable titanium and plastic clips remain in the body permanently, resulting in tissue lesions due to prolonged stimulation of the surrounding tis...
Kailei Xu,Jing Wu,Zehuan Li et al. Kailei Xu et al.
Melanoma remains a formidable clinical challenge due to its high metastatic potential and resistance to conventional therapies, in part reflecting the failure of two-dimensional (2D) culture systems to recapitulate the complex tumor microen...
Chloe E Jones,Stéphane Blouin,Emeline Raguin et al. Chloe E Jones et al.
Osteocytes provide essential functions for the maintenance of healthy bone tissue. They are embedded in lacunar pores within the mineralised bone matrix and communicate through interconnected dendritic cell processes that are housed in cana...
Linya Yan,Qi Xu,Jinfeng Wang et al. Linya Yan et al.
The global incidence of rotator-cuff injuries demands mechanically robust and bioresorbable patches to address the high failure rates of surgical repair. Here, we present a digitally fabricated, warp-knitted silk patch designed to meet this...
Tianbai Wang,Yifan Peng,Bor-Lin Huang et al. Tianbai Wang et al.
TGF-β is conventionally supplemented in culture medium at supraphysiologic doses to accelerate neocartilage development. While enhancing extracellular matrix (ECM) biosynthesis, supraphysiologic TGF-β further promotes non-hyaline cartilag...
Madison R Pickett,Mohini Kamra,David A Castilla-Casadiego et al. Madison R Pickett et al.
The extracellular matrix (ECM) is a dynamic microenvironment that influences cell behavior and fate, with changes in its architecture linked to processes such as differentiation and disease progression in cancer. Pancreatic ductal adenocarc...
Yasaman Samei,Ingrid Cheung,Paraskevi Papavasileiou et al. Yasaman Samei et al.
Human cortical organoids are becoming increasingly popular as models of disease and development in the human brain and as tools for energy-efficient computing. However, their mechanical properties, which are critical to understanding how th...
Pan-Pan Cui,Qi-Chao Yang,Zhi-Jun Sun Pan-Pan Cui
Cancer immunotherapy has changed the landscape of tumor treatment. However, its efficacy is often limited by low response rates and drug resistance, especially in immunologically cold tumors. The recent discovery of cuproptosis, a distinct ...
Pranav Mehta,Ankur Deep Bordoloi,Cor Ravensbergen et al. Pranav Mehta et al.
Breast cancer is the most commonly diagnosed malignancy worldwide, with molecular subtypes following distinct clinical trajectories. While Luminal A breast cancers are typically indolent, a subset enriched in α-smooth muscle actin (α-SMA)...