Angiogenesis and full thickness wound repair in a cell sheet-based vascularized skin substitute [0.03%]
基于细胞片的血管化皮肤移植物的血管生成和全层伤口修复
Adèle Mauroux,Sandrine Gofflo,Josselin Breugnot et al.
Adèle Mauroux et al.
Skin tissue engineering is undergoing tremendous expansion as a result from clinical needs, mandatory replacement of animal models and development of new technologies. Many approaches have been used to produce vascularized skin substitutes ...
Microneedle transdermal drug delivery as a candidate for the treatment of gouty arthritis: Material structure, design strategies and prospects [0.03%]
用于治疗痛风性关节炎的微针透皮给药疗法：材料结构、设计策略和前景展望
Hong Yi,Haojie Yu,Li Wang et al.
Hong Yi et al.
Gouty arthritis (GA) is caused by monosodium urate (MSU) crystals deposition. GA is difficult to cure because of its complex disease mechanism and the tendency to reoccur. GA patients require long-term uric acid-lowering and anti-inflammato...
Unveiling the mechanical role of radial fibers in meniscal tissue: Toward structural biomimetics [0.03%]
半月板组织径向纤维的力学作用及其在结构仿生中的应用研究
Adi Aharonov,Shachar Sofer,Hod Bruck et al.
Adi Aharonov et al.
The meniscus tissue is crucial for knee joint biomechanics and is frequently susceptible to injuries resulting in early-onset osteoarthritis. Consequently, the need for meniscal substitutes spurs ongoing development. The meniscus is a compo...
Tailored environments for directed mesenchymal stromal cell proliferation and differentiation using decellularized extracellular matrices in conjunction with substrate modulus [0.03%]
利用脱细胞基质结合底物模量促进间充质干细胞增殖及定向分化的微环境研究
Michael C Yang,Ian L Chin,Haoyun Fang et al.
Michael C Yang et al.
Decellularised extracellular matrix (dECM) produced by mesenchymal stromal cells (MSCs) is a promising biomaterial for improving the ex vivo expansion of MSCs. The dECMs are often deposited on high modulus surfaces such as tissue culture pl...
Facile fabrications of poly (acrylic acid)-mesoporous zinc phosphate/polydopamine Janus nanoparticles as a biosafe photothermal therapy agent and a pH/NIR-responsive drug carrier [0.03%]
用于生物安全光热治疗和pH/近红外响应药物载体的聚（丙烯酸）-介孔氧化锌磷酸多巴胺 janus 纳米粒子的简便制备法
Wei Gao,Xinyuan Yu,Chunpeng Zhang et al.
Wei Gao et al.
Balancing biocompatibility and drug-loading efficiency in nanoparticles presents a significant challenge. In this study, we describe the facile fabrication of poly (acrylic acid)-mesoporous zinc phosphate/polydopamine (PAA-mZnP/PDA) Janus n...
Osteoinductive biomaterials: Machine learning for prediction and interpretation [0.03%]
骨诱导生物材料：预测与解释的机器学习方法
Sicong Lin,Yan Zhuang,Ke Chen et al.
Sicong Lin et al.
Biomaterials with osteoinductivity are widely used for bone defect repair due to their unique structures and functions. Machine learning (ML) is pivotal in analyzing osteoinductivity and accelerating new material design. However, challenges...
An in situ forming cartilage matrix mimetic hydrogel scavenges ROS and ameliorates osteoarthritis after superficial cartilage injury [0.03%]
一种就地形成的类软骨基质水凝胶可清除ROS并在软骨表层损伤后改善骨关节炎病情
Zhicheng Tong,Yuanzhu Ma,Qiushi Liang et al.
Zhicheng Tong et al.
Superficial cartilage defects represent the most prevalent type of cartilage injury encountered in clinical settings, posing significant treatment challenges. Here, we fabricated a cartilage extracellular matrix mimic hydrogel (GHC, consist...
Mechanical modeling of the petiole-lamina transition zone of peltate leaves [0.03%]
盾形叶叶柄和叶片衔接区域的力学模型研究
Stephan Ritzert,Annabell Rjosk,Hagen Holthusen et al.
Stephan Ritzert et al.
Plant leaves have to deal with various environmental influences. While the mechanical properties of petiole and lamina are generally well studied, only few studies focused on the properties of the transition zone joining petiole and lamina....
Bone cells influence the degradation interface of pure Mg and WE43 materials: Insights from multimodal in vitro analysis [0.03%]
骨细胞对纯镁和WE43材料降解界面的影响：来自多模式体外分析的见解
Diana C Martinez,Anke Borkam-Schuster,Heike Helmholz et al.
Diana C Martinez et al.
In this study, the interaction of pure Mg and WE43 alloy under the presence of osteoblast (OB) and osteoclast (OC) cells and their influence on the degradation of materials have been deeply analyzed. Since OB and OC interaction has an impor...
Cell-free decellularized skin matrix scaffolds: A promising approach for meniscus regeneration in a rabbit meniscectomy model [0.03%]
无细胞脱细胞皮肤基质支架：兔膝关节镜手术半月板再生的潜在方法
Hao Wang,Jie Wu,Liupu Yang et al.
Hao Wang et al.
Tissue engineering presents a promising approach for the treatment of meniscal injuries, yet the development of meniscal scaffolds that exhibit both superior biomechanical properties and biocompatibility remains a considerable challenge. In...